Cardinals vs Blue Jays Prediction 6/10/25 MLB Picks Today

Toronto Blue Jays (36-30) vs. St. Louis Cardinals (36-30)
June 10, 2025 7:45 pm EDT
The Line: St. Louis Cardinals -101 / Toronto Blue Jays -120; Over/Under: 8.5
(Get latest betting odds)

The Toronto Blue Jays and the St. Louis Cardinals meet Tuesday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cardinals vs Blue Jays Prediction.

Starting Pitching Matchup

The Toronto Blue Jays will send out Chris Bassitt for the start here, and Bassitt is 6-3 with a 3.56 ERA and 75 strikeouts this season. In his career, Bassitt is 1-1 with a 7.58 ERA and 11 strikeouts against St. Louis. The St. Louis Cardinals will trot out Miles Mikolas for the start here, and Mikolas is 4-2 with a 3.96 ERA and 36 strikeouts. In his career, Mikolas is 0-0 with a 6.00 ERA and 15 strikeouts against the Blue Jays.

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to build on their 5-4 series-opening win over the Cardinals last time out to sit at 36-30 this season. After this series, the Blue Jays will head on the road again for a rematch against the Philadelphia Phillies.

Blue Jays Pushing For Another Series Win

George Springer has 50 hits and Bo Bichette has 75 hits, with Springer adding 10 home runs, a triple, 15 doubles, and 29 RBIs while Bichette has 17 doubles and 38 RBIs. Andres Gimenez has added 30 hits with 6 doubles and 3 home runs and 10 RBIs this season, along with 9 stolen bases, while Anthony Santander has 55 strikeouts so far this season. Vladimir Guerrero Jr. also has 8 homers, 12 doubles, and 29 RBIs, while Springer also has a .253 batting average and 55 strikeouts up to this point in the year. Daulton Varsho also has 8 home runs and 20 RBIs this season.

Why the Toronto Blue Jays will win

The Blue Jays have won each of their last nine Tuesday night games against NL Central opponents.
The Cardinals have lost each of their last four night games against American League opponents that held a winning record.
The Blue Jays have covered the run line in each of their last eight road games against National League opponents after playing the previous day.
The Cardinals have failed to cover the run line in seven of their last eight games against American League opponents after going to extra innings.

Toronto Blue Jays Player Prop Facts

Chris Bassitt has recorded a win in nine of his last 10 appearances with his team as a road favorite against NL opponents .
Vladimir Guerrero Jr. has scored at least one run in each of the Blue Jays’ last 13 games as favorites.
Chris Bassitt has recorded five or more strikeouts in each of his last 11 appearances against NL opponents.
George Springer has recorded at least one hit in each of the Blue Jays’ last 13 road games against opponents that held a winning record.
Davis Schneider has hit a home run in each of the Blue Jays’ last two games as favorites against the Cardinals.
Daulton Varsho has recorded a Double in four of the Blue Jays’ last five games as road favorites against NL Central opponents.
Andres Gimenez has recorded at least one Single in each of his last six appearances after playing the previous day.
Alejandro Kirk has recorded at least one RBI in each of his last six appearances after playing the previous day.
Chris Bassitt ranks T9th in the league for Wins (6) this season.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to bounce back from their loss in Monday’s series opener to slip to 36-30 on the year. After this series, the Cardinals will head on the road for a series against the Milwaukee Brewers.

Cardinals Drop Back-To-Back Games

Brendan Donovan has a team-high 77 hits along with 20 doubles, 4 home runs, and 26 RBIs, while Lars Nootbaar has 60 hits with 8 home runs, 28 RBIs, 12 doubles, and 4 stolen bases. Nolan Arenado also has 54 hits with 10 doubles, 7 home runs, and 32 RBIs of his own, and Victor Scott II has 45 hits with 8 doubles, a triple, 19 RBIs, and a team-high 17 stolen bases. Willson Contreras has also chipped in 59 hits with 14 doubles, 7 home runs, and 39 RBIs of his own this season. Masyn Winn added 56 points with 11 doubles, 6 home runs, and 22 RBIs, and Alec Burleson added 51 hits with 8 doubles, 5 home runs, and 20 RBIs.

Why the St. Louis Cardinals will win

The Cardinals have won each of their last seven games as home underdogs following a home loss.
The Blue Jays have lost each of their last seven road games after going to extra innings.
The Cardinals have covered the run line in each of their last seven games as home underdogs following a home loss.
The Blue Jays have failed to cover the run line in nine of their last 10 games as road favorites after going to extra innings.

St. Louis Cardinals Player Prop Facts

Nolan Arenado has hit a home run in each of the Cardinals’ last two games as home underdogs against AL opponents.
Miles Mikolas has recorded a win in four of his last five appearances with the Cardinals as underdogs.
Willson Contreras has recorded at least one RBI in each of the Cardinals’ last six games against AL opponents.
Masyn Winn has scored at least one run in eight of the Cardinals’ last nine night games against AL opponents that held a winning record.
Miles Mikolas has recorded three or more strikeouts in each of his last 10 appearances with the Cardinals as home underdogs.
Masyn Winn has recorded at least one hit in each of his nine previous home appearances against AL East opponents.
Masyn Winn has recorded a Double in six of the Cardinals’ last seven games against AL East opponents at Busch Stadium.
Masyn Winn has recorded at least one Single in each of the Cardinals’ last seven night games against opponents that held a winning record.
Brendan Donovan ranks 8th in the league in Hits (77) this season.

Total Runs Facts

Each of the Cardinals’ last eight night games against American League opponents have gone OVER the total runs line.
Ten of the Blue Jays’ last 11 games have gone OVER the total runs line.