Cardinals vs Cubs Prediction 7/3/26 MLB Picks Today

In this article, we will formulate a Cardinals vs Cubs Prediction for this MLB matchup on Friday, July 3^rd in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview

The Chicago Cubs have a 49‑38 record this season and are sitting in the 2nd place of the NL Central. They have a 26‑17 home record and are coming off a 23‑3 home win against the Padres. They will face the Orioles and the Reds next.

The Cubs have a .245 batting average this season, .340 OBP and .414 Slugging percentage. Chicago’s pitching staff has a 4.23 ERA and 1.26 WHIP. Pete Crow‑Armstrong is the team’s best hitter with a .287 batting average, adding a team‑high 19 home runs. Dansby Swanson leads the team in RBI with 57.

David Peterson (L) is the projected starting pitcher for the Cubs, and he has a 4‑6 record, 5.86 ERA and 1.59 WHIP.

St. Louis Cardinals Preview

The St. Louis Cardinals have a 45‑39 record this season and are sitting in the 3rd place of the NL Central. They have a 22‑18 road record and are coming off an 11‑5 road win against the Braves. They will face the Brewers and the Braves next.

The Cardinals have a .246 batting average this season, .323 OBP and .393 Slugging percentage. St. Louis’ pitching staff has a 4.23 ERA and 1.34 WHIP. Jordan Walker is the team’s best hitter with a .291 batting average, also leading the team in RBI with 63 adding a team‑high 19 home runs.

Andre Pallante (R) is the projected starting pitcher for the Cardinals, and he has a 9‑5 record, 3.83 ERA and 1.23 WHIP.

St. Louis Cardinals @ the Chicago Cubs Betting Trends: July 3, 2026

• Probable Starting Pitcher: David Peterson      Record this season: 4-6      ERA: 5.86
• Home Record: 1-3
• Last 5 against Cardinals: 0-0

Why the Chicago Cubs will win

• The Cubs have won each of their last seven home games against NL Central opponents following a home win.
• The Cardinals have lost nine of their last 10 games at Wrigley Field against teams that held a winning record.
• The Cardinals have failed to cover the run line in 10 of their last 11 games after playing the previous day.
• The Cubs have covered the run line in each of their last four home games against the Cardinals.
• The Cubs have led after 3 innings in seven of their last eight home games.
• The Cardinals have trailed after 5 innings in eight of their last nine games at Wrigley Field.
• The Cardinals have lost the first inning in three of their last four games at Wrigley Field.

• Probable Starting Pitcher: Andre Pallante      Record this season: 9-5      ERA: 3.83
• Road Record: 5-0
• Last 5 against Cubs: 0-3

Why the St. Louis Cardinals will win

• The Cubs have lost four of their last five games as favorites against NL Central opponents.
• The Cardinals have won five of their last six games as road underdogs against NL Central opponents following a win.
• The road team has covered the run line in nine of the Cardinals’ last 10 games.
• The Cubs have failed to cover the run line in nine of their last 10 home games against NL Central opponents.
• The Cubs have trailed after 3 innings in four of their last five day games against NL Central opponents.
• The Cardinals have led after 5 innings in four of their last five games against NL Central opponents that held a winning record.

Total Runs Facts

• Each of the Cubs’ last four day games as favorites have gone OVER the total runs line.
• Ten of the Cardinals’ last 12 games against National League opponents have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in seven of David Peterson’s last eight appearances as a starter.
• There has been at least one run scored in the first inning in six of the Cardinals’ last seven games as road underdogs.

Chicago Cubs Player Prop Facts

• Seiya Suzuki has hit a home run in each of the Cubs’ last four home games against the Cardinals.
• David Peterson has recorded four or more strikeouts in each of his last seven Friday appearances with his team as a favorite.
• Seiya Suzuki has recorded at least one hit in each of the Cubs’ last 11 games as favorites against the Cardinals.
• Pete Crow-Armstrong is one of only two players to record 10+ Home Runs and 4+ Triples this season.

St. Louis Cardinals Player Prop Facts

• Nelson Velazquez has hit a home run in three of his last four appearances with the Cardinals as underdogs against NL opponents.
• Nathan Church has recorded at least one hit in each of the Cardinals’ last six day games.
• Andre Pallante has recorded four or more strikeouts in five of his last six appearances with the Cardinals as road underdogs.
• Andre Pallante has recorded a win in each of his last five road appearances.
• Andre Pallante ranks T5th in the league for Wins (9) this season.

Matchup/League Facts

• The Cubs rank 1st in the league for walks this season (390).
• The Cubs rank 30th in the league for home runs allowed this season (132).
• The Cardinals rank 28th in the league for doubles this season (116).
• The Cardinals rank 3rd in the league for strikeouts against this season (646).

Cardinals vs Cubs Prediction

The Cubs are 4-2 in their last 6 meetings against the Cardinals and have won their last four meetings in Chicago.

In this Cardinals vs Cubs Prediction, the Cubs are coming as -130 home favorites. At this point I will have to ride the Cubs the way they have been playing, as they have lost only once in their last 10 games and have scored 32 runs in their last two games. Peterson looked good in his first start with his new team and the Cubs have a superior offense and a better bullpen, while the Cardinals are weaker against lefties. Take the Cubs to win at home.