Cardinals vs Cubs Prediction 7/27/26 MLB Picks Today

In this article we will formulate a Cardinals vs Cubs prediction for this MLB game on Monday, July 27th at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 53-52 this season after they lost two out of three against the Reds by scores of 2-4, 7-0, and 3-5. In game three, St. Louis led 2-1 in the third inning, but they blew the lead and allowed three runs in the 10th for the loss. The Cardinals recorded seven hits in the game and they were led by Burleson, who went 3-5 with one RBI. Leahy allowed six hits and two earned runs over 6.0 innings, while Svanson picked up the loss in relief. Prior to that series, St. Louis lost a makeup game against the Diamondbacks and two out of three against the Angels. 

This season, St. Louis has a 4.13 ERA with a 1.33 WHIP and a .252 opponent batting average, while they have scored 466 runs with a .240 batting average and a .316 on base percentage. Jordan Walker has led the Cardinals with 22 home runs and 77 RBIs, while Alec Burleson has added 15 home runs and 71 RBIs. The projected starting pitcher for St. Louis is Matthew Liberatore, who is 5-7 with a 5.18 ERA and a 1.52 WHIP over 99.0 innings pitched this season. 

Chicago Cubs Betting Preview

The Chicago Cubs are 59-46 this year after they won two out of three against the Pirates by scores of 3-2, 11-0, and 7-8. In game three, Chicago trailed 8-4 in the fifth inning, but they nearly tied the game in the ninth in the loss. The Cubs recorded 12 hits in the game and they were led by Suzuki, who went 1-5 with one home run and two RBIs. Taillon allowed six hits and seven earned runs over 4.0 innings for the loss, while Rolison allowed one earned run in relief. Prior to that series, Chicago lost two out of three against the Tigers, but did win two out of three against the Twins before that. 

This season, Chicago has a 4.23 ERA with a 1.27 WHIP and a .246 opponent batting average, while they have scored 541 runs with a .247 batting average and a .339 on base percentage. Dansby Swanson has led the Cubs with 16 home runs and 61 RBIs, while Ian Happ has added 18 home runs and 45 RBIs. The projected starting pitcher for Chicago is David Peterson, who is 5-7 with a 5.97 ERA and a 1.56 WHIP over 89.0 innings pitched this year. 

Why the St. Louis Cardinals will win

• The Cardinals have won each of their last six games as home underdogs following an extra innings loss.
• The Cubs have lost eight of their last nine Monday games as road favorites against National League opponents.
• The Cardinals have covered the run line in each of their last eight games as underdogs against National League opponents following a loss.
• The Cubs have failed to cover the run line each of their last 10 Monday games against teams that held a winning record.
• The Cardinals have won the first inning in each of their last three home games against opponents that held a winning record.
• The Cardinals have led after 3 innings in four of their last five games as underdogs against NL Central opponents.
• The Cardinals have led after 5 innings in each of their last four night games against National League opponents.

Why the Chicago Cubs will win

• The Cubs have won each of their last four games following a loss.
• The Cardinals have lost five of their last six games against NL Central opponents that held a winning record.
• The Cubs have covered the run line in eight of their last nine road games after playing the previous day.
• The Cardinals have failed to cover the run line in four of their last five home games.
• The Cubs have won the first inning in six of their last eight games as favorites.
• The Cardinals have trailed after 5 innings in four of their last five home games against opponents that held a winning record.

Total Runs Facts

• Each of the Cardinals’ last six night games after playing the previous day have gone UNDER the total runs line.
• Five of the Cubs’ last six games after playing the previous day have gone OVER the total runs line.
• There has been no run scored during the first inning in nine of the Cubs’ last 10 road games.
• There has been no run scored during the first inning in each of the Cardinals’ last six Monday night games.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has recorded two hits in each of the Cardinals’ last four games as underdogs against the Cubs.
• Matthew Liberatore has recorded a win in five of his last six appearances with the Cardinals as home underdogs against NL opponents.
• Matthew Liberatore has recorded six or more strikeouts in each of his last three appearances in night games.
• Lars Nootbaar has hit a home run in two of his last three home appearances against the Cubs.
• Alec Burleson ranks 8th in the league in Hits (116) this season.

Chicago Cubs Player Prop Facts

• Pete Crow-Armstrong has hit a home run in three of the Cubs’ last four night games against opponents that held a winning record.
• David Peterson has recorded a win in three of his last four appearances with his team as a road favorite .
• David Peterson has recorded four or more strikeouts in 11 of his last 12 appearances with his team as a road favorite against NL opponents.
• Pedro Ramirez has recorded at least one hit in each of his last seven appearances.
• Pete Crow-Armstrong ranks T4th in the league in Steals (26) this season.

Matchup/League Facts

• The Cardinals rank 28th in the league for doubles this season (141).
• The Cardinals rank 28th in the league for doubles this season (141).
• The Cubs rank 1st in the league for walks this season (457).
• The Cubs rank 1st in the league for walks this season (457).

Cardinals vs Cubs Prediction 

St. Louis comes into this matchup after losing three of their last four games and they have allowed 19 runs in those three losses. The Cardinals are 27-29 at home this year, while the Cubs are 29-24 on the road. Chicago has split their last four games, but they have scored 7+ runs in three of their last five. The Cubs are starting Peterson, who has allowed two earned runs or fewer in three of his last four starts, while Liberatore has allowed 3+ earned runs in three of his last five outings. Take the over here, as I don’t trust either starter right now.