Cardinals vs Marlins Prediction 4/20/26 MLB Picks Today

In this article, we will formulate a Cardinals vs Marlins Prediction for this MLB matchup on Monday, April 20^th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Miami Marlins Preview

The Miami Marlins have a 10-12 record this season and are sitting in the second place of the NL East. They have a 8-5 home record and are coming off a 5-3 home win against the Brewers. Their previous three games were a 2-5 and a 5-7 home loss against the Brewers, and a 3-6 road loss to the Braves.

The Marlins have a .255 batting average this season, .329 OBP and .391 Slugging percentage. Miami’s pitching staff has a 4.06 ERA and 1.27 WHIP. Otto Lopez is the team’s best hitter with a .338 batting average. Liam Hicks leads the team in RBI with 19, also adding a team‑high 4 home runs.

Max Meyer (R) is the projected starting pitcher for the Marlins, and he has a 1-0 record, 4.12 ERA and 1.32 WHIP.

St. Louis Cardinals Preview

The St. Louis Cardinals have a 13-8 record this season and are sitting in the second place of the NL Central. They have a 6-3 away record and are coming off a 7-5 road win against the Astros. Their previous three games were a 7-5 and a 9-4 road win against the Astros, and a 5-3 home win against the Guardians.

The Cardinals have a .233 batting average this season, .328 OBP and .379 Slugging percentage. St. Louis’ pitching staff has a 4.83 ERA and 1.41 WHIP. Jordan Walker is the team’s best hitter with a .305 batting average, also leading the team in RBI with 16 and adding a team‑high 8 home runs.

Michael McGreevy (R) is the projected starting pitcher for the Cardinals, and he has a 1-1 record, 2.49 ERA and 0.83 WHIP.

St. Louis Cardinals @ Miami Marlins Betting Trends: April 20, 2026

• Probable Starting Pitcher: Max Meyer      Record this season: 1-0      ERA: 4.12
• Home Record: 1-0
• Last 5 against Cardinals: 1-0

Why the Miami Marlins will win

• The Cardinals have lost five of their last six night games against NL East opponents following a win.
• The Marlins have won each of their last four games against National League opponents following a home win.
• The Cardinals have failed to cover the run line in five of their last six games against the Marlins following a win.
• The Marlins have covered the run line in five of their last six night games against NL Central opponents following a home win.
• The Marlins have led after 3 innings in four of their last five games against the Cardinals.
• The Cardinals have trailed after 5 innings in seven of their last eight road games against National League opponents.

• Probable Starting Pitcher: Michael McGreevy      Record this season: 1-1      ERA: 2.49
• Road Record: 1-1
• Last 5 against Marlins: 1-0

Why the St. Louis Cardinals will win

• The Marlins have lost each of their last 14 Monday games as favorites.
• The Cardinals have won each of their last five games as road underdogs.
• The Marlins have failed to cover the run line in each of their last 15 Monday games as favorites.
• The underdogs have covered the run line in seven of the Cardinals’ last eight games at LoanDepot Park.
• The Cardinals have led after 3 innings in three of their last four road games.
• The Marlins have trailed after 5 innings in each of their last eight Monday games as favorites.
• The Cardinals have won the first inning in three of their last four games as road underdogs.

Total Runs Facts

• Each of the Cardinals’ last seven games as underdogs have gone OVER the total runs line.
• Five of the Marlins’ last six home games have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cardinals’ last four night games.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Marlins’ last six Monday games.

Miami Marlins Player Prop Facts

• Kyle Stowers has hit at least one home run in eight of his last 20 home appearances.
• Agustin Ramirez has recorded a hit in each of the Marlins’ last six night games against NL Central opponents that held a winning record.
• Xavier Edwards ranks T2nd in the league in Hits (28) this season.

St. Louis Cardinals Player Prop Facts

• Ramon Urias has hit a home run in three of his last four Monday appearances.
• Lars Nootbaar has recorded at least one hit in each of his last nine road appearances against NL East opponents.
• Jordan Walker ranks T3rd in the league in Home Runs (8) this season.

Matchup/League Facts

• The Marlins rank 1st in the league for triples this season (8).
• The Marlins rank 28th in the league for home runs this season (15).
• The Cardinals rank 30th in the league for strikeouts this season (136).
• The Cardinals rank T29th in the league for triples this season (0).

Cardinals vs Marlins Prediction

The Marlins are 5-3 in their last 8 meetings against the Cardinals but both teams are tied 3-3 in their last six meetings in Miami.

In this Cardinals vs Marlins Prediction, the Marlins are coming as -135 home favorites. Both teams are coming into this matchup in opposite trajectories, as the Cardinals have five consecutive wins and are coming off a series sweep against the Astros where they scored 23 runs in three games. On the flip side, the Marlins are 2-7 in their last 9 games and have 6+ earned runs in five of their last eight games. McGreevy has been looking great for the Cardinals so far, so I like the value with the road dog in this spot. Take the Cardinals on the moneyline for plus money.