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Cardinals vs Marlins Prediction 7-30-25 MLB Picks

Miami Marlins (51-55) vs. St. Louis Cardinals (55-54)
July 30, 2025 7:45 pm EDT
The Line: St. Louis Cardinals -151 / Miami Marlins 124; Over/Under: 8.5
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The Miami Marlins and St. Louis Cardinals meet Wednesday in MLB action at Busch Stadium. Here’s a Cardinals vs Marlins Prediction. This article will include a Cardinals vs Marlins Pick.

Miami Marlins Betting Preview

The Miami Marlins are 51-55 on the year and play the Yankees, Astros, and Braves next. The Miami Marlins are batting .253 on the season, have a .315 OBP, and a .394 slugging percentage. The Miami Marlins pitching staff has a 4.40 ERA and a 1.31 WHIP. Xavier Edwards leads the Miami Marlins with 107 hits and 27 RBI, while Kyle Stowers and Otto Lopez have combined for 186 hits and 118 RBI.

Cal Quantrill gets the ball for the Miami Marlins, and he is 3-8 with a 5.05 ERA and 74 strikeouts this season. Quantrill is 2-0 with a 0.56 ERA and 10 strikeouts in his career against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 55-54 on the year and play the Padres, Dodgers, and Cubs next. The St. Louis Cardinals are batting .250 on the season, have a .321 OBP, and a .391 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.19 ERA and a 1.29 WHIP. Brendan Donovan leads the St. Louis Cardinals with 110 hits and 42 RBI, while Masyn Winn and Willson Contreras have combined for 197 hits and 100 RBI.

Miles Mikolas gets the ball for the St. Louis Cardinals, and he is 6-7 with a 4.94 ERA and 70 strikeouts this season. Mikolas is 4-1 with a 3.33 ERA and 32 strikeouts in his career against the Miami Marlins.

Why the St. Louis Cardinals will win

  • The Cardinals have won each of their last six home games against the Marlins following a loss.
  • The Marlins have lost six of their last seven night games against the Cardinals following a win.
  • The Cardinals have covered the run line in each of their last 10 night games following a loss.
  • The Marlins have failed to cover the run line in each of their last five night games against the Cardinals following a win.
  • The Cardinals have led after 5 innings in three of their last four night games against the Marlins.

Why the Miami Marlins will win

  • The underdogs have won four of the Cardinals’ last five games.
  • The Cardinals have lost each of their last five Wednesday games as favorites.
  • The Marlins have covered the run line in 13 of their last 14 games as road underdogs following a win.
  • The Cardinals have failed to cover the run line in 12 of their last 15 games as home favorites against NL East opponents.
  • The Cardinals have trailed after 5 innings in each of their last five Wednesday games.
  • The Cardinals have trailed after 3 innings in seven of their last eight games against opponents that held a losing record.

St. Louis Cardinals Player Prop Facts

  • Alec Burleson has hit a home run in two of the Cardinals’ last three games as favorites.
  • Miles Mikolas has recorded four or more strikeouts in six of his last eight appearances against NL opponents.
  • Willson Contreras has recorded at least one hit in 15 of his last 16 appearances in night games against NL East teams that held a losing record.
  • Miles Mikolas has recorded a win in each of his last three home appearances against the Marlins.

Miami Marlins Player Prop Facts

  • Jesus Sanchez has hit a home run in three of his last seven appearances against the Cardinals after playing the previous day.
  • Cal Quantrill has recorded three or more strikeouts in each of his last 11 Wednesday appearances with his team as an underdog.
  • Kyle Stowers has recorded at least one hit in each of his last seven appearances against opponents that held a winning record.
  • Kyle Stowers has recorded a Double in each of his last three appearances in night games against NL teams that held a winning record.

Cardinals vs Marlins Prediction

Quantrill hasn’t been good this season, but he’s getting better, allowing 18 hits and eight earned runs in his last 19.2 innings. We can’t say the same for Mikolas, who has allowed 30 hits and 19 runs in his last 20.2 innings. The Marlins also continue to find ways to win and are this scrappy young team that’s gaining confidence and sneaking into the thick of the wild card race. As long as these Marlins continue to play hard, there’s going to be value with the plus money. Give me the Marlins.

Randy Chambers's Free Pick: Miami Marlins +124

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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