Cardinals vs Mets Prediction 4/1/26 MLB Picks Today
NY Mets (3-2) vs. St. Louis Cardinals (3-2)
April 1, 2026 1:15 pm EDT
The Line: St. Louis Cardinals 141 / NY Mets -171; Over/Under: 8
(Get latest betting odds)
In this article we will formulate a Cardinals vs Mets prediction for this MLB game on Wednesday, April 1st at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup.
St. Louis Cardinals Betting Preview
The St. Louis Cardinals are 3-2 this year after they split the first two games in this series by scores of 2-4 and 3-0. In the game two win, St. Louis didn’t generate a ton of offense, but they pitched well and got the shutout victory. The Cardinals recorded six hits in the game and they were led by Herrera, who went 1-2 with two RBIs. Pallante allowed three hits and zero earned runs over 5.0 innings for the win, while O’Brien picked up the save.
This season, St. Louis has a 5.09 ERA with a 1.65 WHIP and a .290 opponent batting average, while they have scored 27 runs with a .251 batting average and a .301 on base percentage. Alec Burleson has led the Cardinals with one home run and five RBIs, while Nolan Gorman has added two home runs and five RBIs. The projected starting pitcher for St. Louis is Matthew Liberatore, who is 0-0 with a 1.80 ERA and a 1.80 WHIP over 5.0 innings pitched this year.
New York Mets Betting Preview
The New York Mets are 3-2 this season after they lost game two in this series by a score of 3-0 on Tuesday night. New York allowed two runs in the third inning and one in the seventh, but they couldn’t find any offense in the shutout loss. The Mets recorded three hits in the game and they were led by Soto, who went 2-4 in the defeat. Senga allowed four hits and two earned runs over 6.0 innings for the loss, while Lovelady allowed one earned run and two hits over 2.0 relief innings.
This season, New York has a 2.87 ERA with a 1.26 WHIP and a .223 opponent batting average, while they have scored 22 runs with a .228 batting average and a .333 on base percentage. Luis Robert has led the Mets with one home run and five RBIs, while Brett Baty has added zero home runs and three RBIs. The projected starting pitcher for New York is Freddy Peralta, who is 1-0 with a 7.20 ERA and a 1.20 WHIP over 5.0 innings pitched this season.
Why the St. Louis Cardinals will win
- The Mets have lost four of their last five games as favorites against the Cardinals following a road loss.
- The underdogs have won six of the Mets’ last eight games at Busch Stadium.
- The Mets have failed to cover the run line in each of their last six Wednesday road games.
- The Cardinals have covered the run line in six of their last seven games against NL East opponents that held a winning record.
- The Cardinals have led after 3 innings in four of their last five home day games.
- The Mets have trailed after 5 innings in each of their last six Wednesday road games.
Why the New York Mets will win
- The Mets have won seven of their last eight games following a loss.
- The Cardinals have lost each of their last four day games against NL East opponents following a home win.
- The Cardinals have failed to cover the run line in each of their last six day games against National League opponents following a win.
- The Mets have covered the run line in seven of their last eight games following a loss.
- The Mets have led after 3 innings in three of their last four games at Busch Stadium against opponents that held a winning record.
- The Mets have led after 5 innings in seven of their last eight day games against NL Central opponents that held a winning record.
Total Runs Facts
- Each of the Mets’ last 10 day games after playing the previous day have gone UNDER the total runs line.
- Each of the Cardinals’ last four home games against National League opponents have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Cardinals’ last six home games against NL East opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Mets’ last 10 day games against NL Central opponents.
St. Louis Cardinals Player Prop Facts
- Nolan Gorman has hit a home run in two of the Cardinals’ last three games.
- Masyn Winn has recorded at least one hit in each of his last nine Wednesday appearances with the Cardinals as underdogs.
New York Mets Player Prop Facts
- Freddy Peralta has recorded seven or more strikeouts in four of his last five appearances in day games.
- Juan Soto has recorded at least one hit in each of his last 11 road appearances against the Cardinals.
- Brett Baty has hit a home run in two of the Mets’ last three day games against NL Central opponents that held a winning record.
Cardinals vs Mets Prediction
St. Louis snapped their two game losing streak with a shutout win on Tuesday night and they will look for their second series win here. The Cardinals have scored just five runs in their last two games and they are starting Liberatore, who pitched very well against the Rays in his first outing. New York has lost two of their last three games, but they have allowed three runs or fewer in three of their last four. The Mets are starting Peralta, who got the win in his first outing, but the Pirates put up some runs on him. I do think New York is the much better team, but they are having some issues at the plate and I want to see how Peralta bounces back. Take the Cardinals and the plus money here.