Washington Nationals (38-54) vs. St. Louis Cardinals (49-44)
July 10, 2025 7:45 pm EDT
The Line: St. Louis Cardinals -144 / Washington Nationals 118; Over/Under: 9
(Get latest betting odds)
In this article, we will formulate a Cardinals vs Nationals prediction for this MLB game on Thursday, July 10, at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup.
Washington Nationals Betting Preview
The Washington Nationals (38-54, 20-26 Away) won back-to-back series against the Los Angeles Angels and Detroit Tigers, but then were swept by the Boston Red Sox at home. Washington opened the series against the Cardinals with a loss, but responded in Game 2 with an 8-2 victory. Nathaniel Lowe led the offense with three RBI, while MacKenzie Gore got the win after allowing one run on five hits with seven strikeouts and one walk across 6.0 innings of work.
This year, the Nationals average 4.42 runs per game (15th in the MLB) on a .247/.313/.391 triple-slash. When it comes to pitching, the Nationals’ staff has a 5.12 ERA (28th) and 1.40 WHIP (26th). James Wood leads the Nationals with a .287 batting average, 24 home runs, and 69 RBI this season.
The projected starting pitcher for the Nationals is Michael Soroka, who is 3-6 in 12 starts this season, with a 5.40 ERA and 1.14 WHIP in 63.1 innings.
St. Louis Cardinals Betting Preview
The St. Louis Cardinals (49-44, 27-18 Home) swept the Cleveland Guardians on the road but then were swept by the Pirates and lost a series to the Cubs. The Cardinals were better than the Nationals in Game 1, but lost the following game, 8-2. Andre Pallante took the loss after allowing seven runs on eight hits with one strikeout and one walk in 6.0 innings.
This season, the Cardinals average 4.52 runs per game (12th in the MLB) on a .251/.321/.393 triple-slash. When it comes to pitching, the Cardinals’ staff has a 4.10 ERA (20th) and 1.27 WHIP (18th). Willson Contreras leads the Cardinals with a .251 batting average, 11 home runs, and 51 RBI this season.
Miles Mikolas will take the mound for the Cardinals on Thursday. The 36-year-old right-hander has a 4-6 record in 17 starts this year with a 5.26 ERA and 1.34 WHIP in 87.1 innings.
Total Runs Facts
- Ten of the Nationals’ last 11 games have gone OVER the total runs line.
- Eight of the last 10 games between the Nationals and Cardinals at Busch Stadium have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Nationals’ last seven night games at Busch Stadium.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Cardinals’ last five games.
Matchup/League Facts
- The Cardinals rank 3rd in the league for walks allowed this season (256).
- The Cardinals rank T4th in the league for home runs allowed this season (87).
- The Nationals rank 4th in the league for strikeouts against this season (693).
- The Nationals rank 27th in the league for hits allowed this season (828).
Cardinals vs Nationals Prediction
The Cardinals won seven of the previous ten H2H encounters, including five of the last six, while this season, St. Louis leads 4-1. Nine of Washington’s last ten games went Over, and considering the starting pitchers for this game, I am going with another Over. Miles Mikolas allowed multiple runs in his previous seven starts and surrendered 14 runs in his last two starts. Michael Soroka wasn’t bad in June, posting a respectable 3.49 ERA, but in the first game in July, he allowed seven runs in 4.0 innings against Boston. Go with Over.
