Cardinals vs Reds Prediction 5/24/26 MLB Picks Today

In this article, we will formulate a Cardinals vs Reds Prediction for this MLB matchup on Sunday, May 24^th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Cincinnati Reds Preview

The Cincinnati Reds have a 27-25 record this season and are sitting in the fourth place of the NL Central. They have a 14-12 home record and are coming off a 7-6 home win against the Cardinals. They will face the Mets and the Braves next.

The Reds have a .227 batting average this season, .310 OBP and .393 Slugging percentage. Cincinnati’s pitching staff has a 4.78 ERA and 1.47 WHIP. Elly De La Cruz is the team’s best hitter with a .288 batting average, also leading the team in RBI with 35 and adding a team-high 12 home runs.

Brady Singer (R) is the projected starting pitcher for the Reds, and he has a 2-4 record, 6.26 ERA and 1.70 WHIP.

St. Louis Cardinals Preview

The St. Louis Cardinals have a 29-22 record this season and are sitting in the second place of the NL Central. They have a 16-9 away record and are coming off a 6-7 road defeat against the Reds. They will face the Brewers and the Cubs next.

The Cardinals have a .242 batting average this season, .323 OBP and .393 Slugging percentage. St. Louis’ pitching staff has a 4.20 ERA and 1.37 WHIP. Jordan Walker is the team’s best hitter with a .302 batting average, also leading the team in RBI with 42 and adding a team-high 15 home runs.

Matthew Liberatore (L) is the projected starting pitcher for the Cardinals, and he has a 2-2 record, 4.70 ERA and 1.55 WHIP.

St. Louis Cardinals @ Cincinnati Reds Betting Trends: May 24, 2026

• Probable Starting Pitcher: Brady Singer      Record this season: 2-4      ERA: 6.26
• Home Record: 2-1
• Last 5 against Cardinals: 2-3

Why the Cincinnati Reds will win

• The Reds have won each of their last six day games at Great American Ball Park after going to extra innings.
• The Cardinals have lost five of their last six day games against National League opponents.
• The Reds have covered the run line in each of their last four games against National League opponents after playing the previous day.
• The Cardinals have failed to cover the run line in each of their last three games after playing the previous day.
• The Cardinals have trailed after 5 innings in five of their last six games.

• Probable Starting Pitcher: Brycen Mautz      Record this season: –      ERA: –
• Road Record: –
• Last 5 against Reds: –

Why the St. Louis Cardinals will win

• The Cardinals have won eight of their last nine games as road underdogs following a loss.
• The Reds have lost each of their last four games as favorites against National League opponents following a win.
• The Cardinals have covered the run line in each of their last nine road games following a loss.
• The Reds have failed to cover the run line in 16 of their last 18 games as home favorites after going to extra innings.
• The Cardinals have won the first inning in three of their last four games as underdogs against the Reds.
• The Cardinals have led after 3 innings in each of their last five road games against NL Central opponents.
• The Cardinals have led after 5 innings in each of their last four games as road underdogs against NL Central opponents.

Total Runs Facts

• Each of the Cardinals’ last six road games after playing the previous day have gone UNDER the total runs line.
• Seven of the Reds’ last eight home games against National League opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Reds’ last eight games as favorites against NL Central opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Cardinals’ last eight games against National League opponents.

Cincinnati Reds Player Prop Facts

• Elly De La Cruz has hit a home run in two of the Reds’ last three home games against opponents that held a winning record.
• Brady Singer has recorded five or more strikeouts in 10 of his last 11 appearances in day games.
• Brady Singer has recorded a win in each of his last six Sunday appearances with his team as a favorite.
• Ke’Bryan Hayes has recorded at least one hit in each of his last seven home appearances against the Cardinals.
• Sal Stewart is one of only two players to record 10+ Home Runs and 10+ Stolen Bases this season.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in four of the Cardinals’ last 16 games against NL opponents.
• Alec Burleson has recorded two hits in each of the Cardinals’ last three games as underdogs.
• Jordan Walker ranks 4th amongst qualified players for Slugging Percentage (.594) this season.

Matchup/League Facts

• The Reds rank 29th in the league for home runs allowed this season (72).
• The Reds rank 28th in the league for walks allowed this season (244).
• The Cardinals rank 29th in the league for strikeouts this season (380).
• The Cardinals rank T28th in the league for triples this season (3).

Cardinals vs Reds Prediction

Both teams are tied 5-5 in their last 10 meetings and are 2-2 in their last 4 meetings in Cincinnati.

In this Cardinals vs Reds Prediction, the Reds are coming as -120 home favorites. I don’t like either pitching in this matchup, as they both have a combined 10.96 ERA and both games in this series have been high-scoring ones. Liberatore has given up 8 runs across his last two starts and Singer has given up 16 runs across his last four and the Reds are better against righties and have a bad bullpen that ranks 28^th in baseball. Take the over 9.5 runs in this one.