Cardinals vs Rockies Prediction 7/22/25 MLB Picks Today

The Saint Louis Cardinals are visiting the Colorado Rockies on Tuesday, July 22^nd at the Coors Field in the second game of this series, with the Cardinals having a 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cardinals vs Rockies Prediction. We will examine:

The Colorado Rockies’ recent form and player performance

The Saint Louis Cardinals’ recent form and player performance

Recent betting trends and streaks involving the Colorado Rockies

Recent betting trends and streaks involving the Saint Louis Cardinals

Recent betting trends in games played between the Saint Louis Cardinals vs Colorado Rockies

A summary that ties it all together and produces a favorable betting outcome for the Saint Louis Cardinals vs Colorado Rockies game

Colorado Rockies Preview

The Colorado Rockies have a 24-76 record this season and are sitting in last place in the NL West. The Rockies have a 12-38 home record and are 40-57 in over/under. They are coming off a 2-6 home defeat by the Cardinals, and have back-to-back losses. Under is 6-1 in their last 7 games, and they are playing the Guardians and the Orioles next.

The Rockies have a .233 batting average this season, .292 OBP, and .383 Slugging percentage. Colorado’s pitching staff has a 5.57 ERA and 1.58 WHIP. Hunter Goodman leads the Rockies with 93 hits, adding a team-high 56 RBI, and he is the team’s best hitter with a .278 batting average. He also adds a team-high 18 home runs.

Bradley Blalock (R) is the projected starting pitcher for the Rockies, and he has a 0-2 record, 9.97 ERA, and 1.80 WHIP.

Saint Louis Cardinals Preview

The Saint Louis Cardinals have a 52-49 record this season and are sitting in third place in the NL Central. The Cardinals have a 23-29 road record and are 53-44 in over/under. They are coming off a 6-2 road victory over the Rockies, which ended their previous three-game losing streak. Over is 9-3-1 in their last 13 games and are playing the Marlins and the Padres next.

The Cardinals have a .253 batting average this season, .321 OBP, and .394 Slugging percentage. Saint Louis’ pitching staff has a 4.17 ERA and 1.27 WHIP. Brendan Donovan leads the Cardinals with 105 hits and is the team’s best hitter with a .293 batting average. Wilson Contreras leads the team in RBI, with 57, adding a team-high 13 home runs.

Erick Fedde (R) is the projected starting pitcher for the Cardinals, and he has a 3-9 record, 4.83 ERA, and 1.47 WHIP.

Why the Colorado Rockies will win

• The Cardinals have lost each of their last six night games following a win.
• The Rockies have won three of their last four games as home underdogs following a loss.
• The Cardinals have failed to cover the run line in each of their last six games against National League opponents following a win.
• The underdogs have covered the run line in six of the Rockies’ last eight games at Coors Field.
• The Cardinals have trailed after 3 innings in seven of their last eight road games.
• The Cardinals have trailed after 5 innings in each of their last six Tuesday games against NL West opponents that held a losing record.

Why the St. Louis Cardinals will win

• The Rockies have lost each of their last 13 night games against National League opponents following a home loss.
• The Cardinals have won seven of their last eight night games against NL West opponents.
• The Rockies have failed to cover the run line in each of their last seven night games following a home loss.
• The Cardinals have covered the run line in each of their last eight Tuesday games against National League opponents.
• The Cardinals have led after 3 innings in four of their last five games against the Rockies.
• The Rockies have trailed after 5 innings in six of their last seven night games against NL Central opponents that held a winning record.

Total Runs Facts

• Each of the Rockies’ last six games against NL Central opponents have gone UNDER the total runs line.
• Four of the Cardinals’ last five games as favorites have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cardinals’ last nine Tuesday games against National League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Rockies’ last four night games against National League opponents.

Matchup/League Facts

• The Rockies rank 1st in the league for triples this season (28).
• The Rockies rank 30th in the league for on-base percentage this season (.292).
• The Cardinals rank T29th in the league for triples this season (4).
• The Cardinals rank 28th in the league for strikeouts this season (733).

Cardinals vs Rockies Prediction

The Cardinals are 4-1 in their last 5 overall meetings against the Rockies, and are 3-1 in their last 4 meetings in Colorado. Under is 6-3-1 in their last 10 meetings.

In this Cardinals vs Rockies Prediction, the Cardinals are coming as -60 road favorites. The Cardinals are rightfully favored, as they have more than twice as many wins as the Rockies, but they have been struggling on the road. Both starting pitchers have been terrible this season, with a combined 14.80 ERA, and Fedde has even worse advanced stats, as he sits on a 5.69 expected ERA. Blalock has been incredibly bad at home for the Rockies, with a 16.76 home ERA in three home games, so I expected a ton of runs in this game. Take the over 12 in this one.