Cardinals vs White Sox Prediction 9/13/26 MLB Picks Today

In this article we will formulate a Cardinals vs White Sox prediction for this MLB game on Sunday, September 13th at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 73-76 this season after they split the first two games by scores of 7-3 and 5-6. In game two, St. Louis led 5-4 in the ninth inning, but they allowed two in the ninth for the loss. The Cardinals recorded eight hits and they committed one error in the game, while they were led by Winn, who went 2-4 with two RBIs. Leahy allowed two hits and zero earned runs over 3.0 innings, while O’Brien blew the save and picked up the loss. Prior to this series, St. Louis lost all three against the Giants, but did win two out of three against the Rockies before that. 

This season, St. Louis has a 4.31 ERA with a 1.35 WHIP and a .254 opponent batting average, while they have scored 680 runs with a .244 batting average and a .317 on base percentage. Jordan Walker has led the Cardinals with 28 home runs and 100 RBIs, while Alec Burleson has added 22 home runs and 106 RBIs. The projected starting pitcher for St. Louis is Michael McGreevy, who is 6-9 with a 3.92 ERA and a 1.25 WHIP over 154.0 innings pitched this season. 

Chicago White Sox Betting Preview

The Chicago White Sox are 76-72 this year after they won game two by a score of 6-5 last night. Chicago erased a 4-1 deficit in the fifth inning and they hit the winning home run with two outs in the ninth for the victory. The White Sox recorded six hits and they committed two errors in the game, while they were led by Grichuk, who went 1-4 with one home run and two RBIs. Newcomb opened the game, while Hicks got the win and Hudson picked up the save. Prior to this series, Chicago lost all three against the Pirates, but did win two out of three against the Twins before that. 

This season, Chicago has a 4.16 ERA with a 1.31 WHIP and a .242 opponent batting average, while they have scored 694 runs with a .235 batting average and a .319 on base percentage. Colson Montgomery has led the White Sox with 31 home runs and 84 RBIs, while Miguel Vargas has added 30 home runs and 79 RBIs. The projected starting pitcher for Chicago is Sean Burke, who is 8-7 with a 3.58 ERA and a 1.20 WHIP over 156.0 innings pitched this year. 

Why the St. Louis Cardinals will win

• The White Sox have lost each of their last seven games against NL opponents following a win.
• The Cardinals have won six of their last seven day games against AL opponents following a loss.
• The White Sox have failed to cover the run line in each of their last seven games against NL opponents.
• The Cardinals have covered the run line in each of their last six games following a home loss.
• The Cardinals have won the first inning in each of their last three day games against opponents that held a winning record.
• The Cardinals have led after 5 innings in eight of their last 10 day games.
• The Cardinals have led after 3 innings in each of their last five games against the White Sox.

Why the Chicago White Sox will win

• The Cardinals have lost each of their last four games after playing the previous day.
• The road team has won six of the last seven games between the White Sox and Cardinals.
• The Cardinals have failed to cover the run line in four of their last five day games against AL Central opponents that held a winning record.
• The White Sox have covered the run line in nine of their last 12 road games against NL Central opponents that held a losing record.
• The Cardinals have lost the first inning in three of their last four day games.
• The White Sox have led after 3 innings in seven of their last eight Sunday games against NL Central opponents that held a losing record.

Total Runs Facts

• Each of the Cardinals’ last seven home games against AL opponents have gone OVER the total runs line.
• Each of the White Sox’s last six day games after playing the previous day have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in 11 of Michael McGreevy’s last 12 appearances as a starter.
• There has been at least one run scored in the first inning in 15 of the White Sox’s last 17 day games against NL Central opponents.

St. Louis Cardinals Player Prop Facts

• Michael McGreevy has recorded four or more strikeouts in six of his last seven appearances.
• Nathan Church has recorded at least one hit in each of the Cardinals’ last 11 games.
• Leo Bernal has hit a home run in two of the Cardinals’ last three games.

Chicago White Sox Player Prop Facts

• Miguel Vargas has recorded at least one hit in each of the White Sox’s last 17 road games against NL opponents.
• Sean Burke has recorded a win in each of his last three road appearances against NL opponents.
• Chase Meidroth has hit at least one home run in two of the White Sox’s last three road games against NL opponents that held a losing record.

Matchup/League Facts

• The Cardinals rank 4th in the league for home runs allowed this season (149).
• The Cardinals rank 26th in the league for slugging percentage this season (.386).
• The White Sox rank 26th in the league for batting average this season (.235).
• The White Sox rank 26th in the league for strikeouts against this season (1357).

Cardinals vs White Sox Prediction 

St. Louis comes into this matchup after a terrible loss on Saturday night and they have dropped four of their last five. The Cardinals are 35-39 at home this year, while the White Sox are 33-41 on the road. Chicago has also lost four of their last five games and they have scored three or fewer in all four losses. The White Sox are starting Burke, who has allowed 7, 0, 2, 4, and 4 earned runs in his last five starts, while McGreevy has allowed 2, 4, 7, and 3 earned runs in his last four outings. Take the over here.