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Cubs vs Mets Prediction 9/24/25 MLB Picks Today

NY Mets (81-76) vs. Chicago Cubs (88-69)
September 24, 2025 8:05 pm EDT
The Line: Chicago Cubs -126 / NY Mets +104; Over/Under: 7
(Get latest betting odds)

The New York Mets and the Chicago Cubs meet Wednesday in MLB action from Citi Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cubs vs Mets Prediction.

Starting Pitching Matchup

The New York Mets will send out Jonah Tong for the start here and Tong is 2-2 with a 5.94 ERA and 21 strikeouts this season. This will be Tong’s first career start against the Cubs. Matthew Boyd will get the nod for the Cubs here and is 13-8 with a 3.20 ERA and 151 strikeouts this season. In his career, Boyd is 1-0 with a 4.09 ERA and 13 strikeouts against the Mets.


New York Mets Recap

The New York Mets come into this game looking to add on to their 9-7 win over the Cubs from Tuesday’s matchup to sit at 81-76 this season. After this series, the Mets will head on the road for a division series against the Marlins in Miami.

Mets Snap Two-Game Skid

Pete Alonso has 164 hits with 38 doubles, 37 home runs, 122 RBIs and a .274 batting average while Juan Soto has 148 hits with 20 doubles, 35 stolen bases, 42 home runs and 104 RBIs on the year. Francisco Lindor has 166 hits with 31 stolen bases along with 34 doubles, 28 home runs and 80 RBIs while Mark Vientos has 17 home runs and 60 RBIs, but also has 109 strikeouts so far this season. Brandon Nimmo has also added 146 hits with 27 doubles and 24 home runs and 88 RBIs this season. Luis Torrens has also chipped in 14 doubles and Luisangel Acuna has 15 stolen bases as well this season.

Why the New York Mets will win

  • The underdogs have won each of the Mets’ last four games at Wrigley Field.
  • The Cubs have lost four of their last five games as home favorites against National League opponents.
  • The Cubs have failed to cover the run line in each of their last seven games as home favorites after playing the previous day.
  • The Mets have covered the run line in each of their last six games as underdogs against the Cubs.

New York Mets Player Prop Facts

  • Francisco Lindor has hit a home run in four of the Mets’ last five games against the Cubs.
  • Juan Soto has recorded at least one hit in each of the Mets’ last 13 road games against NL Central opponents.
  • Juan Soto ranks 2nd amongst qualified players for On Base Percentage (.399) this season.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to rebound from their loss at the hands of the Mets on Tuesday to fall to 88-69 this season. After this set, the Cubs will head home for a division series against the St. Louis Cardinals.

Cubs Lose 5th Game In A Row

Ian Happ has 132 hits with 29 doubles, 23 home runs and 74 RBIs. Kyle Tucker has 132 hits including 25 doubles, 4 triples, 22 home runs and 73 RBIs while Seiya Suzuki also has 133 hits with 30 doubles and 27 home runs and 91 RBIs of his own. Pete Crow-Armstrong also has contributed 140 hits, 37 doubles, 4 triples, 29 home runs and 90 RBIs as well this season. Dansby Swanson has added 23 home runs and 76 RBIs, while also having 165 strikeouts and Suzuki has 159 strikeouts so far this season. Crow-Armstrong also has a team-high 35 stolen bases while Nico Hoerner has 28 stolen bases this season. Tucker’s also added 25 stolen bases while Michael Busch has also chipped in 22 doubles, 4 triples, 30 home runs and 82 RBIs this season.

Why the Chicago Cubs will win

  • The Mets have lost each of their last seven road games after playing the previous day.
  • The Cubs have won five of their last six home games following a home loss.
  • The Mets have failed to cover the run line in each of their last seven games against NL Central opponents following a win.
  • The Cubs have covered the run line in each of their last four home games against the Mets following a home loss.

Chicago Cubs Player Prop Facts

  • Nico Hoerner has recorded two or more hits in each of the Cubs’ last five home games.
  • Matthew Boyd has recorded five or more strikeouts in three of his last four appearances against NL opponents.
  • Matthew Boyd has recorded a win in seven of his last eight home appearances against NL opponents.
  • Ian Happ has recorded at least one Double in four of the Cubs’ last five home games against NL East opponents that held a winning record.
  • Kyle Tucker has hit a home run in five of his last nine appearances in night games against NL East teams that held a winning record.
  • Nico Hoerner ranks 5th in the league in Hits (174) this season.

Total Runs Facts

  • Each of the Mets’ last nine night games as underdogs have gone OVER the total runs line.
  • Five of the Cubs’ last six night games against NL East opponents have gone UNDER the total runs line.

Cubs vs Mets Prediction

I’m on the Cubs in this one. Admittedly, the Cubs have not looked very good since clinching their playoff spot, but Jonah Tong hasn’t looked major league ready pretty much at all this season. I think the Cubs can bounce back and get to him here. Matthew Boyd hasn’t looked very good in his own right as of late, but he’s still been really strong at home this season and I think he bounces back, and the Cubs do as well as a result. Give me the Cubs.

Chris Ruffolo's Free Pick: Chicago Cubs -126

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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