Cleveland Guardians vs Kansas City Royals Prediction 9/10/25 MLB Picks Today

The Kansas City Royals and the Cleveland Guardians meet Wednesday in MLB action from Progressive Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Kansas City Royals vs. Cleveland Guardians prediction.

Starting Pitching Matchup

The Kansas City Royals will send out Jonathan Bowlan for the start here and Bowlan is 1-2 with a 3.57 ERA and 35 strikeouts this season. This will be Bowlan’s first career start against the Guardians. Logan Allen will get the start for the Guardians and is 7-11 with a 4.46 ERA and 109 strikeouts this season. In his last five starts against the Royals, Allen is 0-4 with a 6.26 ERA and 15 strikeouts.

Kansas City Royals Recap

The Kansas City Royals come into this game looking to rebound from their 2-0 loss at the hands of the Guardians on Tuesday to sit at 73-72 on the year. After this series, the Royals will head on the road for a series against the Philadelphia Phillies.

Royals Drop Three In A Row

Bobby Witt Jr. has 161 hits with 41 doubles and 34 stolen bases along with 5 triples, 21 home runs and 77 RBIs while Vinnie Pasquantino has 143 hits with 24 doubles, a triple, 29 home runs and 99 RBIs. Maikel Garcia’s added 154 hits with 35 doubles, 5 triples, 16 home runs and 67 RBIs and 22 stolen bases and Salvador Perez also has 33 doubles, 25 home runs and 81 RBIs but also has 112 strikeouts so far this season.

Why the Kansas City Royals will win

• The Royals have covered the run line in each of their last 13 Wednesday road games.
• The Guardians have failed to cover the run line in seven of their last eight Wednesday night games against AL Central opponents.

Kansas City Royals Player Prop Facts

• Maikel Garcia has hit a home run in three of the Royals’ last six games against opponents that held a winning record.
• Bobby Witt Jr. has recorded at least one hit in each of his last 24 road appearances against AL Central opponents that held a winning record.
• Bobby Witt Jr. ranks 3rd in the league in Hits (161) this season.

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to add on to their win over the Royals on Tuesday to improve to sit at 74-70 this season. After this series, the Guardians will take on the Chicago White sox in a series at home.

Guardians Win 5 In A Row

Steven Kwan has 152 hits as part of a .275 batting average and 10 home runs, 25 doubles and 48 RBIs. Kyle Manzardo has 97 hits with 15 doubles, 2 triples, 25 home runs and 65 RBIs as well this year. Gabriel Arias has 20 doubles but also 139 strikeouts and Manzardo has 119 strikeouts so far this season. Arias has also added 10 home runs and 48 RBIs and Jose Ramirez has chipped in 28 home runs and 76 RBIs with 37 stolen bases as well. Carlos Santana has also added 89 hits with 11 home runs and 52 RBIs as well this season.

Why the Cleveland Guardians will win

• The Royals have lost 13 of their last 14 night games against AL Central opponents that held a winning record.
• The Guardians have won each of their last seven night games against American League opponents following a home win.
• The Guardians have covered the run line each of their last eight night games against AL Central opponents that held a winning record.
• The Royals have failed to cover the run line in 13 of their last 14 night games against AL Central opponents that held a winning record.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in three of the Guardians’ last four home games against AL Central opponents.
• Jose Ramirez has recorded at least one hit in each of the Guardians’ last 13 night games against AL Central opponents that held a winning record.
• Jose Ramirez has recorded a Double in three of the Guardians’ last four games against opponents that held a winning record.
• Jose Ramirez ranks T3rd in the league in Steals (37) this season.

Total Runs Facts

• Nine of the Royals’ last 11 games have gone UNDER the total runs line.
• Three of the Guardians’ last four games have gone UNDER the total runs line.

Kansas City Royals vs. Cleveland Guardians Prediction

I’m on the under in this one. I get the case to be made for either side here, but I don’t really trust either offensive lineup right now, as the Guardians haven’t been the most consistent across the board and KC has really struggled offensively in this series, and I just think this one flies under the total. Give me the under here.