Guardians vs Twins Prediction 8-1-25 MLB Picks

The Minnesota Twins and the Cleveland Guardians meet Friday in MLB action from Progressive Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Guardians vs Twins Prediction.

Starting Pitching Matchup

The Minnesota Twins will send out Joe Ryan here, and Ryan is 10-5 with a 2.82 ERA and 137 strikeouts this season. In his last five starts against the Guardians, Ryan is 1-4 with a 2.67 ERA and 23 strikeouts. Gavin Williams will get the nod for the Guardians here and is 6-4 with a 3.51 ERA and 109 strikeouts this season. In his last five starts against the Twins, Williams is 3-2 with a 3.38 ERA and 22 strikeouts.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to rebound from a 13-1 loss at the hands of the Boston Red Sox last time out to sit at 51-57 on the year. After this series, the Twins will head on the road for a series against the Detroit Tigers.

Twins Drop 4 Of Their Last 5 Games

Byron Buxton has 92 hits along with 14 doubles, a team-high 23 home runs, and 59 RBIs with 17 stolen bases and 4 triples, while Trevor Larnach chipped in 85 hits with 15 doubles, 13 home runs, and 43 RBIs as well this season. Brooks Lee has contributed 78 hits with 10 doubles, 10 home runs, and 43 RBIs, and Matt Wallner has 13 homers and 22 RBIs as well.

Why the Minnesota Twins will win

• The underdogs have won four of the Twins’ last five games.
• The Guardians have lost each of their last three home games against AL Central opponents.
• The underdogs have covered the run line in each of the last 13 games between the Twins and Guardians.
• The Guardians have failed to cover the run line in four of their last five games against American League opponents that held a losing record.

Minnesota Twins Player Prop Facts

• Joe Ryan has recorded seven or more strikeouts in four of his last five appearances with the Twins as underdogs against AL opponents.
• Ryan Jeffers has recorded at least one hit in each of his last six appearances after not playing the previous day.
• Ryan Jeffers has recorded a Double in three of his last four road appearances against the Guardians after not playing the previous day.
• Byron Buxton has hit a home run in three of his last four road appearances after not playing the previous day.
• Joe Ryan ranks T8th in the league for Wins (10) this season.

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to add on to their 5-0 win over the Colorado Rockies last time out to sit at 54-54 on the year. After this series, the Guardians will head on the road for an interleague series against the New York Mets.

Guardians Win Back-To-Back Games To Win Series

Steven Kwan has 115 hits as part of a .286 batting average and 9 home runs, 20 doubles, and 38 RBIs. Kyle Manzardo has 71 hits with 13 doubles, 2 triples, 18 home runs and 47 RBIs as well this year. Gabriel Arias has 19 doubles but also 94 strikeouts, and Manzardo has 86 strikeouts so far this season. Arias has also added 7 home runs and 34 RBIs, and Jose Ramirez has chipped in 21 home runs and 56 RBIs with 31 stolen bases as well. Carlos Santana has also added 81 hits with 11 home runs and 46 RBIs this season.

Why the Cleveland Guardians will win

• The Twins have lost each of their last seven games against the Guardians following a home loss.
• The Guardians have won each of their last 12 Friday night games as home favorites against AL Central opponents.
• The Twins have failed to cover the run line in each of their last seven road games following a home loss.
• The Guardians have covered the run line in seven of their last eight night games against AL Central opponents.

Cleveland Guardians Player Prop Facts

• Carlos Santana has hit a home run in each of the Guardians’ last two games against the Twins.
• Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
• Will Brennan has recorded at least one hit in each of his last nine appearances against the Twins.
• Jose Ramirez ranks 4th in the league in Steals (31) this season.

Total Runs Facts

• Each of the Twins’ last five night games against AL Central opponents have gone UNDER the total runs line.
• Six of the Guardians’ last seven night games against American League opponents have gone OVER the total runs line.

Guardians vs Twins Prediction

I’m leaning towards the Guardians here. I think that the Guardians at least have their bullpen intact, which is big when we get to the later stages of the game, as I think this is going to be a tight matchup. The Twins also unloaded a lot of pieces in their lineup at the deadline. I think it’s going to take a bit of time for this lineup to get some cohesion going, and I could see them struggling just enough to fall short here. Give me the Guardians.