Colorado Rockies vs Arizona Diamondbacks Prediction 9/23/26 MLB Picks Today

The Arizona Diamondbacks and the Colorado Rockies meet Wednesday in MLB action from Coors Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Arizona Diamondbacks vs. Colorado Rockies prediction.

Starting Pitching Matchup

The Arizona Diamondbacks will send out Merrill Kelly for the start here and Kelly is 9-14 with a 5.00 ERA and 111 strikeouts this season. Mason Adams will start for the Rockies and is 0-1 with a 5.09 ERA and 23 strikeouts this season.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to build on their 7-2 win over the Rockies from Tuesday’s series opener to sit at 83-74 this season. After this series, the Diamondbacks will head on the road for a game against the San Diego Padres.

Diamondbacks Win 3 Straight

Going into Tuesday, Gabriel Moreno leads the Diamondbacks with a team-high 139 hits while adding 32 doubles, a triple, 15 home runs, and 75 RBIs so far this season. Geraldo Perdomo has added 138 hits with 19 doubles, 7 triples, 9 home runs, and 52 RBIs, while Corbin Carroll has logged 134 hits with 31 doubles, 16 triples, 22 home runs, and 72 RBIs on the year. Ketel Marte has contributed 134 hits with 29 doubles, 3 triples, 22 home runs, and 74 RBIs. Nolan Arenado leads Arizona across the board in home runs and RBIs with a team-high 27 home runs and 78 RBIs alongside 126 hits, 23 doubles, and a triple. Ildemaro Vargas has chipped in 113 hits with 19 doubles, 5 triples, 9 home runs, and 67 RBIs up to this point in the season.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from their loss at the hands of Arizona on Tuesday to fall to 57-100 this season. After this series, the Rockies will head on the road for a series against the Chicago White Sox.

Rockies Drop 9 Of Last 11

Entering Tuesday, TJ Rumfield leads the Rockies with a team-high 159 hits while adding 29 doubles, 3 triples, 15 home runs, and 70 RBIs so far this season. Jake McCarthy has added 156 hits with 30 doubles, 13 triples, 15 home runs, and a team-high 83 RBIs, while Hunter Goodman leads Colorado with 39 home runs alongside 121 hits, 19 doubles, 2 triples, and 82 RBIs on the year. Willi Castro has contributed 111 hits with 20 doubles, a triple, 15 home runs, and 56 RBIs, while Troy Johnston has logged 109 hits with 31 doubles, a triple, 4 home runs, and 50 RBIs. Ezequiel Tovar has chipped in 96 hits with 22 doubles, 11 home runs, and 42 RBIs for Colorado up to this point in the season.

Arizona Diamondbacks @ Colorado Rockies Betting Trends: September 23, 2026

• Probable Starting Pitcher: Mason Adams      Record this season: 0-1      ERA: 5.09
• Home Record: 0-1
• Last 5 against Diamondbacks: –

Why the Colorado Rockies will win

• The Rockies have won three of their last four games as home underdogs against the Diamondbacks following a home loss.
• The Diamondbacks have lost three of their last four games as favorites against the Rockies following a road win.
• The Diamondbacks have failed to cover the run line in eight of their last nine games as favorites after playing the previous day.
• The Rockies have covered the run line in eight of their last nine night games at Coors Field following a loss.
• The Diamondbacks have trailed after 3 innings in three of their last four games as favorites.
• The Diamondbacks have trailed after 5 innings in each of their last six Wednesday games against NL opponents that held a losing record.

• Probable Starting Pitcher: Merrill Kelly      Record this season: 9-14      ERA: 5.00
• Road Record: 5-8
• Last 5 against Rockies: 3-1

Why the Arizona Diamondbacks will win

• The Rockies have lost 13 of their last 14 games against teams that held a winning record.
• The Diamondbacks have won five of their last six road games.
• The Diamondbacks have covered the run line in four of their last five road games.
• The Rockies have failed to cover the run line each of their last three games against teams that held a winning record.
• The Diamondbacks have won the first inning in each of their last five games against the Rockies.
• The Diamondbacks have led after 3 innings in seven of their last eight night games against the Rockies.
• The Rockies have trailed after 5 innings in each of their last 13 night games against opponents that held a winning record.

Total Runs Facts

• Each of the Diamondbacks’ last seven road games have gone UNDER the total runs line.
• Seven of the Rockies’ last eight night games against NL opponents have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of the Diamondbacks’ last seven night games at Coors Field.
• There has been at least one run scored in the first inning in each of the Rockies’ last six games against NL opponents.

Colorado Rockies Player Prop Facts

• Kyle Karros has hit a home run in each of his last four Wednesday appearances against NL teams that held a winning record.
• Mason Adams has recorded five or more strikeouts in four of his five previous appearances.
• Hunter Goodman has recorded two hits in four of his last five home appearances against NL West opponents.
• TJ Rumfield ranks 3rd amongst qualified players for On Base Percentage (.389) this season.

Arizona Diamondbacks Player Prop Facts

• Nolan Arenado has hit a home run in three of the Diamondbacks’ last four games as favorites.
• Ketel Marte has recorded two or more hits in seven of his last eight appearances against the Rockies after playing the previous day.
• Merrill Kelly has recorded four or more strikeouts in 10 of his last 11 road appearances against NL West opponents.
• Merrill Kelly has recorded a win in each of his last four road appearances against NL West opponents.
• Gabriel Moreno ranks 4th amongst qualified players for Batting Average (.306) this season.

Matchup/League Facts

• The Rockies rank 1st in the league for triples this season (39).
• The Rockies rank 30th in the league for ERA this season (5.58).
• The Diamondbacks rank 2nd in the league for triples this season (38).
• The Diamondbacks rank 29th in the league for strikeouts this season (1105).

Arizona Diamondbacks vs. Colorado Rockies Prediction

I’m on the over in this game. I don’t trust Merrill Kelly’s game on the road at Coors as Kelly has been a hard pitcher to trust season long. On the flipside, Mason Adams has had big time issues of his own, and I think that this ends up being a high-scoring game between these two so give me the over here.