
Rockies vs Marlins Prediction 9/17/25 MLB Picks Today
Miami Marlins (71-80) vs. Colorado Rockies (41-109)
September 17, 2025 8:40 pm EDT
The Line: Colorado Rockies +134 / Miami Marlins -164; Over/Under: 10.5
(Get latest betting odds)
The Miami Marlins and the Colorado Rockies meet Wednesday in MLB action from Coors Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Rockies vs Marlins Prediction.
Starting Pitching Matchup
The Miami Marlins will give the start to Ryan Weathers here and Weathers is 2-1 with a 2.73 ERA and 27 strikeouts this season. In his career, Weathers is 0-1 with a 9.69 ERA and 8 strikeouts against the Rockies. McCade Brown will get ther start for the Rockies and is 0-4 with a 9.88 ERA and 10 strikeouts this season. This will be Brown’s first career start against Miami.
Miami Marlins Recap
The Miami Marlins come into this game looking to add on to their 6-5 win over the Rockies from Tuesday’s series opener to sit at 71-80 on the year. After this set, the Marlins will take on the Texas Rangers in an interleague series on the road.
Marlins Get Back On Track
Xavier Edwards has 148 hits including 20 doubles and a team-high 24 stolen bases while Eric Wagaman has 111 hits with 27 doubles. Otto Lopez has 123 hits with 18 doubles and 14 home runs with 73 RBIs. Kyle Stowers has 115 hits with 21 doubles, 3 triples, 25 home runs and 73 RBIs but also has 125 strikeouts so far this season. Agustin Ramirez also has 20 home runs, 29 doubles and 63 RBIs on the year.
Why the Miami Marlins will win
- The Marlins have won each of their last eight road games against NL West opponents.
- The Rockies have lost each of their last eight home games against NL East opponents.
- The Marlins have covered the run line in each of their last eight road games against NL West opponents following a win.
- The Rockies have failed to cover the run line in 11 of their last 12 games after playing the previous day.
Colorado Rockies Recap
The Colorado Rockies come into this game looking to rebound from their loss to the Marlins on Tuesday to slide to 41-110 this season. After this series, the Rockies will welcome the Los Angeles Angels to town for an interleague series at Coors Field.
Rockies Drop 9 Of Their Last 10
Hunter Goodman leads the Rockies with 136 hits including 26 doubles, 4 triples, 30 home runs and 87 RBIs while Michael Toglia has 58 hits with 15 doubles, 11 home runs and 32 RBIs but also has 132 strikeouts. Kyle Farmer has 14 doubles while Jordan Beck has 15 home runs, 26 doubles, 51 RBIs, 5 triples and 17 stolen bases. Brenton Doyle has 111 hits with 21 doubles, 14 home runs, 55 RBIs and 16 stolen bases. Mickey Moniak has 107 hits with 17 doubles, 8 triples and 21 home runs with 62 RBIs.
Why the Colorado Rockies will win
- The Marlins have lost each of their last six road games against the Rockies following a win.
- The underdogs have won four of the last five games between the Marlins and Rockies.
- The Marlins have failed to cover the run line each of their last seven road games against teams that held a losing record.
- The Rockies have covered the run line in each of their last six games against NL East opponents.
Colorado Rockies Player Prop Facts
- Thairo Estrada has recorded a Double in three of his last four appearances against the Marlins.
- Tyler Freeman has recorded at least one hit in each of his last 16 appearances against NL East opponents.
- Brenton Doyle has hit a home run in four of his last eight appearances in night games against teams that held a losing record.
Total Runs Facts
- Each of the Marlins’ last six road games against NL West opponents have gone OVER the total runs line.
- Four of the Rockies’ last five night games against NL East opponents have gone OVER the total runs line.
Rockies vs Marlins Prediction
I’m on the Marlins in this one. It’s a bit of a heftier price than I’d like to lay with Miami, but the fact is that I don’t trust the Rockies against a decent lefty like Weathers. I think the Marlins can get to McCade Brown, who has been very hittable this season. I’ll side with the Marlins to get the job done on Wednesday as well. Give me Miami here.