Cubs vs Giants Prediction 5/7/25 MLB Picks Today

The San Francisco Giants and the Chicago Cubs meet Wednesday in MLB action from Wrigley Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cubs vs Giants Prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Robbie Ray for the start here, and Ray is 4-0 with a 3.05 ERA and 41 strikeouts this season. In his last five starts against the Cubs, Ray is 2-0 with a 2.10 ERA and 28 strikeouts. Ben Brown will get the start for the Cubs here and is 3-2 with a 4.88 ERA and 35 strikeouts this season. This will be Brown’s first career start against the Giants.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to add on to their 14-5 win over the Cubs from Tuesday’s matchup to improve to 23-14 on the year. After this series, the Giants will head on the road once again for an interleague series against the Minnesota Twins.

Giants Win 4 Of Their Last 5

Jung Hoo Lee leads the Giants with 40 hits, including a team-high 11 doubles, along with a pair of triples, 3 home runs, and 20 RBIs with 3 stolen bases, while Heliot Ramos has 32 hits with 7 doubles, 5 home runs, and 12 RBIs. Wilmer Flores also has a team-high 7 home runs and 31 RBIs, while Mike Yastrzemski has 5 home runs with 17 RBIs and 7 doubles, and Tyler Fitzgerald has a team-high 5 stolen bases as well on the year.

Why the San Francisco Giants will win

• The Giants have won each of their last six games as road underdogs after going to extra innings.
• The Cubs have lost four of their last five games as favorites against the Giants following a home loss.
• The Giants have covered the run line in each of their last seven games as road underdogs after going to extra innings.
• The Cubs have failed to cover the run line each of their last nine Wednesday games against National League opponents that held a winning record.

San Francisco Giants Player Prop Facts

• LaMonte Wade Jr has hit a home run in three of his last four appearances with the Giants as underdogs against the Cubs.
• Heliot Ramos has scored at least one run in 10 of the Giants’ last 11 road games against NL opponents.
• Jung Hoo Lee has recorded at least one Single in each of his last 12 appearances with the Giants as underdogs against NL opponents.
• Jung Hoo Lee has recorded at least one hit in each of his last 12 appearances with the Giants as underdogs against NL opponents.
• Casey Schmitt has recorded at least one Double in four of his last five appearances in day games against NL Central teams that held a winning record.
• Casey Schmitt has recorded at least one RBI in four of his last five road appearances against NL opponents that held a winning record.
• Robbie Ray ranks T8th in the league for Wins (4) this season.

Chicago Cubs Recap

The Chicago Cubs will be looking to bounce back after the loss to the Giants on Tuesday to slip to 22-15 on the year. After this series, the Cubs will duke it out in a road series against the New York Mets.

Cubs Looking For Consistency In Series Rubber Match

Ian Happ has a team-high 43 hits with 9 doubles, 3 home runs, and 19 RBIs. Kyle Tucker has 40 hits, including 8 doubles, 9 home runs, and 30 RBIs, while Seiya Suzuki also has 35 hits with 6 doubles and 9 home runs and 31 RBIs of his own. Miguel Amaya added 6 doubles and 14 RBIs, and Pete Crow-Armstrong has also contributed 10 doubles this season. Dansby Swanson has added 7 home runs and 20 RBIs, while he also has the unfortunate distinction of leading the Cubs with 44 strikeouts so far this season. Crow-Armstrong also has a team-high 12 stolen bases, while Nico Hoerner has 7 stolen bases this season. Tucker’s also added 9 stolen bases while Michael Busch has also chipped in 6 home runs and 22 RBIs this season.

Why the Chicago Cubs will win

• The Cubs have won each of their last seven day games against NL West opponents following a loss.
• The Giants have lost each of their last eight games as underdogs against NL Central opponents following a win.
• The Giants have failed to cover the run line each of their last 10 day games against NL Central opponents that held a winning record.
• The Cubs have covered the run line in six of their last seven day games against NL West opponents following a loss.

Chicago Cubs Player Prop Facts

• Ian Happ has hit a home run in two of the Cubs’ last three games against the Giants.
• Ian Happ has recorded at least one RBI in six of the Cubs’ last seven games as favorites against the Giants.
• Dansby Swanson has scored at least one run in seven of the Cubs’ last eight games.
• Justin Turner has recorded at least one Single in 14 of his last 15 appearances with his team as a home favorite against NL West opponents.
• Justin Turner has recorded at least one hit in each of his last 12 appearances with his team as a favorite against the Giants.
• Pete Crow-Armstrong ranks 4th in the league in Steals (12) this season.

Total Runs Facts

• Each of the Giants’ last 12 games as underdogs have gone OVER the total runs line.
• Each of the Cubs’ last five games as favorites against the Giants have gone OVER the total runs line.

Cubs vs Giants Prediction

I’m on the Cubs here. The Giants have been a team that can provide value on the road this season, but the fact of the matter is that the Cubs have been one of the best teams in baseball against left-handed pitching. I think it could be a tricky start for Robbie Ray here. Ben Brown isn’t my top go-to option in this Chicago rotation, but in the end, I think the Cubs do enough to grab the win here. Give me Chicago.