Cubs vs Guardians Prediction 7/2/25 MLB Picks Today

The Cleveland Guardians and Chicago Cubs meet Wednesday in MLB action at Wrigley Field. Here’s a Cubs vs Guardians Prediction. This article will include a Cubs vs Guardians Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 40-43 on the year and play the Tigers, Astros, and White Sox next. The Cleveland Guardians are batting .225 on the season, have a .297 OBP, and a .364 slugging percentage. The Cleveland Guardians’ pitching staff has a 4.05 ERA and a 1.38 WHIP. Steven Kwan leads the Cleveland Guardians with 92 hits and 25 RBI, while Jose Ramirez and Carlos Santana have combined for 156 hits and 75 RBI.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 4-8 with a 3.90 ERA and 82 strikeouts this season. This will be Bibee’s second career game against the Chicago Cubs.

Chicago Cubs Betting Preview

The Chicago Cubs are 50-35 on the year and play the Cardinals, Twins, and Yankees next. The Chicago Cubs are batting .257 on the season, have a .326 OBP, and a .446 slugging percentage. The Chicago Cubs pitching staff has a 3.84 ERA and a 1.24 WHIP. Kyle Tucker leads the Chicago Cubs with 92 hits and 52 RBI, while Nico Hoerner and Pete Crow-Armstrong have combined for 177 hits and 97 RBI.

Shota Imanaga gets the ball for the Chicago Cubs, and he is 4-2 with a 2.54 ERA and 37 strikeouts this season. This will be Imanaga’s second career game against the Cleveland Guardians.

Why the Chicago Cubs will win

• The Cubs have won each of their last six games against American League opponents that held a losing record.
• The Guardians have lost each of their last six night games against NL Central opponents.
• The Guardians have failed to cover the run line each of their last seven games against teams that held a winning record.
• The Cubs have covered the run line in each of their last six games as favorites against AL Central opponents.
• The Cubs have led after 3 innings in each of their last seven games as favorites against American League opponents.
• The Cubs have led after 5 innings in each of their last five home night games.
• The Cubs have won the first inning in four of their last five games as favorites against American League opponents.

Why the Cleveland Guardians will win

• The Cubs have lost each of their last three games as favorites against the Guardians following a win.
• The Guardians have won each of their last five Wednesday games as underdogs.
• The Cubs have failed to cover the run line in eight of their last nine night games against AL Central opponents following a win.
• The road team has covered the run line in eight of the Guardians’ last nine games.
• The Guardians have won the first inning in each of their last five Wednesday games against opponents that held a winning record.
• The Guardians have led after 3 innings in each of their last five Wednesday games against opponents that held a winning record.

Chicago Cubs Player Prop Facts

• Kyle Tucker has hit a home run in three of his last four appearances in night games against AL teams that held a losing record.
• Kyle Tucker has recorded at least one hit in nine of his last 10 appearances against the Guardians.
• Shota Imanaga has recorded four or more strikeouts in each of his last 11 appearances at Wrigley Field.
• Carson Kelly has recorded at least one Double in three of his last four appearances against AL opponents.
• Shota Imanaga has recorded a win in each of his last four appearances in night games against teams that held a losing record.
• Pete Crow-Armstrong ranks 3rd in the league in Steals (25) this season.

Cleveland Guardians Player Prop Facts

• Carlos Santana has hit a home run in three of his last six appearances in night games against NL Central teams that held a winning record.
• Will Brennan has recorded a hit in each of his six previous appearances against the Cubs.
• Jose Ramirez ranks 9th in the league in Steals (21) this season.

Cubs vs Guardians Prediction

The Guardians have lost five straight games, and they’ve scored two or fewer runs in four of those games. It’s hard to take the Guardians seriously in their current form, and Bibee has a 4.96 ERA and .259 allowed batting average in 52.2 road innings. Imanaga has pitched just twice since May, but we know what he’s capable of when he’s right, and he has a 2.54 ERA, 1.03 WHIP, and .198 allowed batting average on the season. I’ll roll with the Cubs on Wednesday night.