Cubs vs Guardians Prediction 7/3/25 MLB Picks Today

The Cleveland Guardians and Chicago Cubs meet Thursday in MLB action at Wrigley Field. Here’s a Cubs vs Guardians Prediction. This article will include a Cubs vs Guardians Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 40-44 on the year and play the Tigers, Astros, and White Sox next. The Cleveland Guardians are batting .225 on the season, have a .297 OBP, and a .365 slugging percentage. The Cleveland Guardians’ pitching staff has a 4.07 ERA and a 1.39 WHIP. Steven Kwan leads the Cleveland Guardians with 92 hits and 26 RBI, while Jose Ramirez and Carlos Santana have combined for 158 hits and 76 RBI.

Luis Ortiz gets the ball for the Cleveland Guardians, and he is 4-9 with a 4.36 ERA and 96 strikeouts this season. Ortiz is 0-2 with a 3.75 ERA and 12 strikeouts in his career against the Chicago Cubs.

Chicago Cubs Betting Preview

The Chicago Cubs are 51-35 on the year and play the Cardinals, Twins, and Yankees next. The Chicago Cubs are batting .257 on the season, have a .327 OBP, and a .446 slugging percentage. The Chicago Cubs pitching staff has a 3.83 ERA and a 1.24 WHIP. Kyle Tucker leads the Chicago Cubs with 93 hits and 52 RBI, while Nico Hoerner and Pete Crow-Armstrong have combined for 179 hits and 99 RBI.

Cade Horton gets the ball for the Chicago Cubs, and he is 3-2 with a 4.80 ERA and 33 strikeouts this season. This will be Horton’s first career game against the Cleveland Guardians.

Why the Chicago Cubs will win

• The Cubs have won each of their last seven games against American League opponents that held a losing record.
• The Guardians have lost each of their last seven night games against NL Central opponents.
• The Guardians have failed to cover the run line in seven of their last eight games against teams that held a winning record.
• The Cubs have covered the run line in six of their last seven games as favorites against AL Central opponents.
• The Cubs have led after 3 innings in seven of their last eight games as favorites against American League opponents.
• The Cubs have led after 5 innings in each of their last six home night games.

Why the Cleveland Guardians will win

• The Cubs have lost three of their last four games as favorites against the Guardians following a win.
• The Cubs have failed to cover the run line in each of their last six night games against AL Central opponents following a home win.
• The road team has covered the run line in nine of the Guardians’ last 10 games.
• The Cubs have trailed after 3 innings in four of their last five night games against AL Central opponents that held a losing record.

Chicago Cubs Player Prop Facts

• Kyle Tucker has hit a home run in three of his last five appearances in night games against AL teams that held a losing record.
• Dansby Swanson has recorded at least one hit in each of the Cubs’ last six night games.
• Pete Crow-Armstrong ranks 3rd in the league in Steals (26) this season.

Cleveland Guardians Player Prop Facts

• Carlos Santana has hit a home run in three of his last five appearances in night games against NL Central teams that held a winning record.
• Will Brennan has recorded a hit in each of his six previous appearances against the Cubs.
• Jose Ramirez ranks T9th in the league in Steals (21) this season.

Cubs vs Guardians Prediction

The Guardians have lost six straight games and just blew a 3-0 lead yesterday. I want nothing to do with the Guardians in their current form. Ortiz also has a 5.18 ERA and .241 allowed batting average in 48.2 road innings. Horton hasn’t been good in his last two starts, but he’s better at home than on the road, as he has a 3.38 ERA compared to a 6.08 ERA. Still, the Cubs keep finding ways to win and have the offense to make up for a subpar pitching performance. We can’t say the same for the Guardians. Give me the Cubs.