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Cubs vs Marlins Prediction 5/14/25 MLB Picks Today

Miami Marlins (15-26) vs. Chicago Cubs (25-18)
May 14, 2025 7:40 pm EDT
The Line: Chicago Cubs -225 / Miami Marlins +185; Over/Under: 9
(Get latest betting odds)

The Miami Marlins and the Chicago Cubs meet Wednesday in MLB action from Wrigley Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cubs vs Marlins Prediction.

Starting Pitching Matchup

The Miami Marlins will send out Ryan Weathers for the start here and Weathers was 5-6 with a 3.63 ERA and 80 strikeouts last season. In his career, Weathers is 1-2 with an 8.80 ERA and 10 strikeouts against the Cubs. Jameson Taillon will get the start for the Cubs here and Taillon is 2-2 with a 4.53 ERA and 35 strikeouts this season. In his career, Taillon is 3-0 with a 0.83 ERA and 15 strikeouts against the Marlins.

Miami Marlins Recap

The Miami Marlins come into this game looking to bounce back from a 5-4 loss at the hands of the Cubs in Tuesday’s matchup to fall to 15-26 on the year. After this series, the Marlins will head home for an interleague series against the Tampa Bay Rays.

Marlins Lose Three Straight & Seven Of Last Nine

Xavier Edwards leads the Marlins with 41 hits including 3 doubles and a team-high 11 stolen bases while Eric Wagaman has 31 hits with 8 doubles. Otto Lopez has 25 hits with 5 doubles and a pair of home runs with 11 RBIs and Matt Mervis has a team-high 7 home runs and 14 RBIs so far this year. Kyle Stowers has 37 hits with 4 doubles, a triple, 7 home runs and 26 RBIs but also has 43 strikeouts while Mervis has 40 K’s as well so far this season.

Why the Miami Marlins will win

  • The Cubs have lost five of their last six Wednesday games as favorites.
  • The Marlins have won each of their last three Wednesday night games as underdogs against NL Central opponents.
  • The Cubs have failed to cover the run line in each of their last six night games against the Marlins at Wrigley Field following a win.
  • The Marlins have covered the run line in six of their last seven night games against the Cubs at Wrigley Field following a loss.

Miami Marlins Player Prop Facts

  • Jesus Sanchez has hit a home run in five of his last 22 appearances against NL Central opponents.
  • Jesus Sanchez has recorded an RBI in three of the Marlins’ last four games against NL opponents.
  • Jesus Sanchez has recorded at least one Single in each of the Marlins’ last five night games against NL opponents that held a winning record.
  • Jesus Sanchez has recorded at least one hit in each of the Marlins’ last six night games against NL opponents that held a winning record.
  • Otto Lopez has scored at least one run in seven of his last eight appearances with the Marlins as underdogs against NL Central opponents.
  • Xavier Edwards ranks T7th in the league in Steals (11) this season.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to finish off the sweep of Miami after Tuesday’s win brought them to 25-18 on the year. After this series, the Cubs will take on the Chicago White Sox in a crosstown interleague series.

Cubs Pick Up Back-To-Back Wins

Ian Happ has a team-high 43 hits with 9 doubles, 3 home runs and 19 RBIs. Kyle Tucker has 43 hits including 8 doubles, 10 home runs and 32 RBIs while Seiya Suzuki also has 37 hits with 7 doubles and 9 home runs and 32 RBIs of his own. Miguel Amaya’s added 6 doubles and 18 RBIs and Pete Crow-Armstrong also has contributed 11 doubles, 10 home runs and 28 RBIs as well this season. Dansby Swanson has added 8 home runs and 22 RBIs, while he also has the unfortunate distinction of leading the Cubs with 49 strikeouts so far this season. Crow-Armstrong also has a team-high 13 stolen bases while Nico Hoerner has 7 stolen bases this season. Tucker’s also added 10 stolen bases while Michael Busch has also chipped in 7 home runs and 24 RBIs this season.

Why the Chicago Cubs will win

  • The Marlins have lost each of their last seven road games against teams that held a winning record.
  • The Cubs have won eight of their last nine games against NL East opponents that held a losing record.
  • The Marlins have failed to cover the run line in seven of their last eight Wednesday games against teams that held a winning record.

Chicago Cubs Player Prop Facts

  • Dansby Swanson has hit a home run in five of the Cubs’ last eight games against NL opponents that held a losing record.
  • Justin Turner has recorded a Double in five of his last six appearances with his team as a favorite against the Marlins.
  • Justin Turner has recorded at least one RBI in each of his last four home appearances against opponents that held a losing record.
  • Dansby Swanson has scored at least one run in nine of the Cubs’ last 10 night games against NL opponents that held a losing record.
  • Nico Hoerner has recorded at least one Single in each of the Cubs’ last nine night games.
  • Nico Hoerner has recorded at least one hit in each of the Cubs’ last 11 night games.
  • Jameson Taillon has recorded a win in each of his last four appearances against NL East opponents that held a losing record.
  • Pete Crow-Armstrong ranks 5th in the league in Steals (13) this season.

Total Runs Facts

  • Seven of the Marlins’ last eight road games against National League opponents have gone OVER the total runs line.
  • Six of the Cubs’ last seven games as favorites against NL East opponents have gone UNDER the total runs line.

Cubs vs Marlins Prediction

I’m on the Cubs here. Chicago has started to wake up again in this series, and I am at the point where I’ve sold all of my Marlins stock as Miami’s value is gone. The Fish are back to looking like the team that many of us expected to see coming into the year with one of the least potent lineups in baseball. Taillon’s been decent this season, and he has fantastic numbers in his career against the Marlins. I think Chicago gets the job done here, so give me the Cubbies.

Chris Ruffolo's Free Pick: Chicago Cubs -225

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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