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Cubs vs Marlins Prediction 9/24/26 MLB Picks Today

Miami Marlins (78-80) vs. Chicago Cubs (87-71)
September 24, 2026 2:20 pm EDT
The Line: Chicago Cubs -206 / Miami Marlins 169; Over/Under: 7.5
(Get latest betting odds)

The Miami Marlins and Chicago Cubs meet Thursday in MLB action at Wrigley Field. Here’s a Cubs vs Marlins Prediction. This article will include a Cubs vs Marlins Pick.

Miami Marlins Betting Preview

The Miami Marlins are 78-80 on the year and play the Braves next. The Miami Marlins are batting .249 on the season, have a .327 OBP, and have a .400 slugging percentage. The Miami Marlins’ pitching staff has a 4.11 ERA and a 1.29 WHIP. Otto Lopez leads the Miami Marlins with 187 hits and 71 RBI, while Xavier Edwards and Javier Sanoja have combined for 276 hits and 120 RBI.

Tyler Phillips gets the ball for the Miami Marlins, and he is 5-6 with a 3.45 ERA and 99 strikeouts this season. Phillips is 1-0 with a 4.50 ERA and 3 strikeouts in his career against the Chicago Cubs.

Chicago Cubs Betting Preview

The Chicago Cubs are 87-71 on the year and play the Red Sox next. The Chicago Cubs are batting .251 on the season, with a .339 OBP and a .430 slugging percentage. The Chicago Cubs’ pitching staff has a 4.17 ERA and a 1.26 WHIP. Pete Crow-Armstrong leads the Chicago Cubs with 172 hits and 107 RBI, while Alex Bregman and Nico Hoerner have combined for 319 hits and 160 RBI.

Matthew Boyd gets the ball for the Chicago Cubs, and he is 9-5 with a 4.06 ERA and 93 strikeouts this season. This will be Boyd’s second career game against the Miami Marlins.

Why the Chicago Cubs will win

  • The Marlins have lost each of their last six Thursday road games.
  • The Cubs have won five of their last six home games against the Marlins following a loss.
  • The Cubs have covered the run line in 11 of their last 13 day games against NL East opponents following a home loss.
  • The Marlins have failed to cover the run line in each of their last five Thursday road games.
  • The Cubs have led after 5 innings in each of their last five home day games.
  • The Cubs have led after 3 innings in four of their last five home day games.

Why the Miami Marlins will win

  • The Marlins have won each of their last three games as underdogs against the Cubs.
  • The Cubs have lost three of their last four games as home favorites.
  • The Marlins have covered the run line in each of their last 11 road games against NL Central opponents following a win.
  • The Cubs have failed to cover the run line each of their last four home games against teams that held a losing record.
  • The Marlins have led after 3 innings in eight of their last 10 day games against NL Central opponents that held a winning record.
  • The Marlins have led after 5 innings in six of their last eight day games against NL Central opponents that held a winning record.

Total Runs Facts

  • Seven of the Cubs’ last eight home games against NL East opponents have gone OVER the total runs line.
  • Five of the Marlins’ last six day games against NL opponents have gone OVER the total runs line.
  • There has been no run scored during the first inning in each of the Marlins’ last 15 games against NL Central opponents.
  • There has been no run scored during the first inning in each of the Cubs’ last 10 Thursday games against NL opponents.

Chicago Cubs Player Prop Facts

  • Pete Crow-Armstrong has hit at least one home run in three of the Cubs’ last four day games against opponents that held a losing record.
  • Ian Happ has recorded at least one hit in each of the Cubs’ last 10 home games against NL East opponents that held a losing record.
  • Pete Crow-Armstrong ranks T1st in the league in Home Runs (45) this season.

Miami Marlins Player Prop Facts

  • Kyle Stowers has hit at least one home run in each of the Marlins’ last four road games against the Cubs.
  • Griffin Conine has recorded at least one hit in each of the Marlins’ last eight games against NL Central opponents that held a winning record.
  • Otto Lopez ranks 1st in the league in Hits (187) this season.

Matchup/League Facts

  • The Cubs rank 1st in the league for runs scored this season (839).
  • The Cubs rank 1st in the league for RBIs this season (793).
  • The Marlins rank 3rd in the league for triples this season (35).
  • The Marlins rank 3rd in the league for steals this season (161).

Cubs vs Marlins Prediction

I’m not excited to back the Marlins with how they’ve run out of gas over the last couple of months. However, we’re getting big plus money with Phillips on the mound, who has been solid with a 3.45 ERA and 1.31 WHIP through 122.2 innings. The Marlins have also outplayed the Cubs in this series already, and they’re a young team that’s not done competing. Boyd has been hittable this season, especially at home, where he has a 5.53 ERA and a .271 allowed batting average through 53.2 innings. I’ll take a shot with the road dogs at this price.

Randy Chambers's Free Pick: Miami Marlins 169

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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