Diamondbacks vs Astros Prediction 7-22-25 MLB Picks Today

In this article, we will formulate a Diamondbacks vs Astros prediction for this MLB game on Tuesday, July 22, at Chase Field in Phoenix, Arizona. Let’s take a look at the prediction for this MLB matchup.

Houston Astros Betting Preview

The Houston Astros (58-42, 25-23 Away) were swept by the Cleveland Guardians and lost a series to the Texas Rangers to end the first half. Houston then opened the second half with a loss to the Seattle Mariners, but defeated the Diamondbacks 6-3 in Game 1 of the current series. Brice Matthews had the best game of his young career as he blasted a pair of homers and led the offense with five RBI. Colton Gordon got the win after allowing three runs (two earned) on seven hits with four strikeouts and two walks in 5.2 innings.

This season, the Astros average 4.42 runs per game (14th in the MLB) on a .259/.323/.410 triple-slash. When it comes to pitching, the Astros’ staff has a 3.62 ERA (6th) and 1.17 WHIP (2nd). Jose Altuve leads the Astros with a .278 batting average, 17 home runs, and 53 RBI this season.

Framber Valdez will take the mound for the Astros on Tuesday. The 31-year-old left-hander has a 10-4 record in 19 starts this year with a 2.75 ERA and 1.12 WHIP in 121.0 innings.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks (50-51, 26-26 Home) opened the second half of the season with a sweep of the St. Louis Cardinals, responding to a five-series losing streak. However, Arizona returned to losing ways in Game 1 against the Astros on Monday, taking a 6-3 defeat. Zac Gallen took the loss after allowing six runs on seven hits with six strikeouts and one walk in 6.0 innings.

This year, the Diamondbacks average 5.13 runs per game (4th in the MLB) on a .252/.329/.447 triple-slash. When it comes to pitching, the Diamondbacks’ staff has a 4.60 ERA (25th) and 1.33 WHIP (23rd). Eugenio Suarez leads the Diamondbacks with a .257 batting average, 36 home runs, and 86 RBI this season.

The projected starting pitcher for the Diamondbacks is Eduardo Rodriguez, who is 3-6 in 16 starts this season, with a 5.94 ERA and 1.67 WHIP in 80.1 innings.

Why the Astros will beat the Diamondbacks

• The Astros have won seven of their last eight games against National League opponents.
• The Diamondbacks have lost each of their last four night games after playing the previous day.
• The Astros have covered the run line in each of their last six road games after playing the previous day.
• The Diamondbacks have failed to cover the run line in four of their last five night games at Chase Field following a home loss.
• The Astros have led after 5 innings in each of their last three games against the Diamondbacks at Chase Field.
• The Astros have led after 3 innings in three of their last four games against National League opponents.

Total Runs Facts

• Six of the Diamondbacks’ last seven night games as underdogs have gone OVER the total runs line.
• Three of the Astros’ last four games as favorites against National League opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 11 of the Diamondbacks’ last 12 night games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last five night games against National League opponents.

Matchup/League Facts

• The Diamondbacks rank 2nd in the league for walks this season (362).
• The Diamondbacks rank 3rd in the league for RBIs this season (506).
• The Astros rank 2nd in the league for opponent batting average this season (.225).
• The Astros rank 2nd in the league for hits allowed this season (746).

Diamondbacks vs Astros Prediction

The Astros won seven of the previous ten H2H encounters, including six of the last seven. I am backing Houston to get another win on Tuesday because of Framber Valdez, who has been outstanding this season. Valdez registered three shutouts in his last four starts and allowed more than three runs just twice this year. Eduardo Rodriguez, on the other hand, was excellent in June, posting a 1.98 ERA, but in his previous two starts, he surrendered 12 runs, and I think his poor form will continue here. Go with Houston.