Diamondbacks vs Astros Prediction 7-23-25 MLB Picks

The Houston Astros and Arizona Diamondbacks meet Wednesday in MLB action at Chase Field. Here’s a Diamondbacks vs Astros Prediction. This article will include a Diamondbacks vs Astros Pick.

Houston Astros Betting Preview

The Houston Astros are 59-42 on the year and play the Athletics, Nationals, and Red Sox next. The Houston Astros are batting .259 on the season, have a .324 OBP, and a .410 slugging percentage. The Houston Astros pitching staff has a 3.59 ERA and a 1.17 WHIP. Jose Altuve leads the Houston Astros with 106 hits and 53 RBI, while Jeremy Pena and Isaac Paredes have combined for 193 hits and 90 RBI.

Brandon Walter gets the ball for the Houston Astros, and he is 1-3 with a 3.66 ERA and 47 strikeouts this season. This will be Walter’s first career game against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 50-52 on the year and play the Pirates, Tigers, and Athletics next. The Arizona Diamondbacks are batting .253 on the season, have a .329 OBP, and a .445 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.58 ERA and a 1.33 WHIP. Geraldo Perdomo leads the Arizona Diamondbacks with 102 hits and 72 RBI, while Josh Naylor and Eugenio Suarez have combined for 194 hits and 144 RBI.

Brandon Pfaadt gets the ball for the Arizona Diamondbacks, and he is 10-6 with a 4.82 ERA and 90 strikeouts this season. This will be Pfaadt’s second career game against the Houston Astros.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won five of their last six day games against AL West opponents.
• The Astros have lost four of their last five day games against National League opponents that held a losing record.
• The Diamondbacks have covered the run line in seven of their last eight games as favorites against AL West opponents.
• The Astros have failed to cover the run line in seven of their last eight games against teams that held a losing record.
• The Diamondbacks have led after 3 innings in four of their last five home day games.
• The Diamondbacks have won the first inning in three of their last four games against opponents that held a winning record.
• The Astros have trailed after 5 innings in each of their last five day games against opponents that held a losing record.

Why the Houston Astros will win

• The Astros have won each of their last six games as underdogs against National League opponents.
• The Diamondbacks have lost four of their last five games as favorites against American League opponents.
• The Astros have covered the run line in each of their last seven games as underdogs against National League opponents.
• The Diamondbacks have failed to cover the run line in four of their last five home games against American League opponents.
• The Astros have led after 3 innings in four of their last five games as underdogs against National League opponents.
• The Diamondbacks have lost the first inning in four of their last five day games against AL West opponents that held a winning record.
• The Diamondbacks have trailed after 5 innings in each of their last six day games against AL West opponents that held a winning record.

Arizona Diamondbacks Player Prop Facts

• Eugenio Suarez has hit at least one home run in each of the Diamondbacks’ last five day games against opponents that held a winning record.
• Josh Naylor has recorded a Double in three of his last four appearances in day games against AL West teams that held a winning record.
• Josh Naylor has recorded at least one hit in each of his last nine home appearances against the Astros after playing the previous day.
• Brandon Pfaadt has recorded a win in each of his last four appearances with the Diamondbacks as favorites against AL opponents.
• Brandon Pfaadt has recorded five or more strikeouts in each of his last seven appearances in day games against teams that held a winning record.
• Corbin Carroll ranks 7th amongst qualified players for Slugging Percentage (.558) this season.

Houston Astros Player Prop Facts

• Yainer Diaz has hit a home run in each of his last two appearances with the Astros as underdogs against NL West opponents.
• Jose Altuve has recorded a Double in four of the Astros’ last five games against the Diamondbacks.
• Christian Walker has recorded at least one hit in each of his last 15 road appearances against NL West opponents.

Diamondbacks vs Astros Prediction

The Astros have had their way in this series, but it’s only a matter of time before the Diamondbacks pick up offensively. Walter isn’t the same pitcher on the road, where he has a 4.82 ERA and .264 allowed batting average. Pfaadt is dealing this month, allowing 14 hits and six runs in his last 21 innings. In 53.1 home innings, Pfaadt has a 3.71 ERA. This feels like a spot where the Diamondbacks can bounce back and avoid the sweep. Give me the Diamondbacks.