Diamondbacks vs Dodgers Prediction 9/23/25 MLB Picks Today

The Los Angeles Dodgers and Arizona Diamondbacks meet Tuesday in MLB action at Chase Field. Here’s a Diamondbacks vs Dodgers Prediction. This article will include a Diamondbacks vs Dodgers Pick.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 88-68 on the year and play the Mariners next. The Los Angeles Dodgers are batting .254 on the season, have a .329 OBP, and a .440 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.02 ERA and a 1.26 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 167 hits and 99 RBI, while Freddie Freeman and Andy Pages have combined for 313 hits and 167 RBI.

Shohei Ohtani gets the ball for the Los Angeles Dodgers, and he is 1-1 with a 3.29 ERA and 54 strikeouts this season. This will be Ohtani’s second career game against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 79-77 on the year and play the Padres next. The Arizona Diamondbacks are batting .252 on the season, have a .325 OBP, and a .435 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.43 ERA and a 1.31 WHIP. Geraldo Perdomo leads the Arizona Diamondbacks with 166 hits and 97 RBI while Corbin Carroll and Ketel Marte have combined for 272 hits and 153 RBI.

Brandon Pfaadt gets the ball for the Arizona Diamondbacks, and he is 13-8 with a 5.02 ERA and 138 strikeouts this season. Pfaadt is 4-2 with a 5.11 ERA and 37 strikeouts in his career against the Los Angeles Dodgers.

Los Angeles Dodgers @ Arizona Diamondbacks Betting Trends: September 23, 2025

• Probable Starting Pitcher: Brandon Pfaadt      Record this season: 13-8      ERA: 5.02
• Home Record: 9-3
• Last 5 against Dodgers: 4-0

Why the Arizona Diamondbacks will win

• The Diamondbacks have won each of their last five games as home underdogs.
• The Dodgers have lost four of their last five games as road favorites against National League opponents.
• The Diamondbacks have covered the run line in each of their last 12 games as underdogs following a win.
• The Dodgers have failed to cover the run line in each of their last eight games against the Diamondbacks following a home loss.
• The Diamondbacks have led after 5 innings in each of their last seven games as home underdogs against National League opponents.
• The Dodgers have trailed after 3 innings in six of their last seven road games against National League opponents.
• The Diamondbacks have won the first inning in each of their last six games as home underdogs against National League opponents.

• Probable Starting Pitcher: Shohei Ohtani      Record this season: 1-1      ERA: 3.29
• Road Record: 0-1
• Last 5 against Diamondbacks: 0-0

Why the Los Angeles Dodgers will win

• The Diamondbacks have lost seven of their last eight games against the Dodgers following a home win.
• The Dodgers have won seven of their last eight night games against NL West opponents.
• The Diamondbacks have failed to cover the run line in each of their last five home games against the Dodgers following a win.
• The Dodgers have covered the run line in each of their last four games as road favorites against the Diamondbacks following a loss.
• The Dodgers have led after 3 innings in three of their last four games as road favorites.
• The Dodgers have led after 5 innings in eight of their last nine games against opponents that held a winning record.

Total Runs Facts

• Four of the last five games between the Dodgers and Diamondbacks have gone UNDER the total runs line.
• Four of the Dodgers’ last five games as road favorites have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 16 of the Diamondbacks’ last 17 home games against National League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Dodgers’ last five night games against NL West opponents.

Arizona Diamondbacks Player Prop Facts

• Corbin Carroll has hit a home run in each of the Diamondbacks’ last two games against the Dodgers.
• Brandon Pfaadt has recorded six or more strikeouts in five of his last six appearances with the Diamondbacks as home underdogs.
• Geraldo Perdomo has recorded at least one hit in each of the Diamondbacks’ last 18 home games against NL opponents.
• Brandon Pfaadt has recorded a win in six of his last seven appearances with the Diamondbacks as home underdogs.
• Geraldo Perdomo has recorded a Double in each of the Diamondbacks’ last four night games.
• Geraldo Perdomo ranks 5th amongst qualified players for On Base Percentage (.391) this season.

Los Angeles Dodgers Player Prop Facts

• Freddie Freeman has hit at least one home run in four of the Dodgers’ last five games as road favorites against the Diamondbacks.
• Teoscar Hernandez has recorded a Double in each of his last three appearances with the Dodgers as road favorites against the Diamondbacks.
• Will Smith has recorded at least one hit in each of the Dodgers’ last 11 games as road favorites against the Diamondbacks.
• Shohei Ohtani ranks T2nd in the league in Home Runs (53) this season.

Matchup/League Facts

• The Diamondbacks rank 1st in the league for triples this season (37).
• The Diamondbacks rank 3rd in the league for RBIs this season (752).
• The Dodgers rank T2nd in the league for runs scored this season (794).
• The Dodgers rank 2nd in the league for home runs this season (232).

Diamondbacks vs Dodgers Prediction

Big series, as the Dodgers are fighting for the NL West crown, while the Diamondbacks are I the thick of the wild card race. The value is with the Diamondbacks and the plus money. Ohtani still isn’t going deep into games, and the Dodgers have lost 5 of the last 6 games he’s pitched. Pfaadt has been a mess all season, but he’s allowed just 16 hits and 6 runs in his last 19.2 innings. This is the best Pfaadt has looked this season. Pfaadt has also been solid in 91.1 home innings, racking up a 3.15 ERA and .254 allowed batting average. Give me the Diamondbacks and the more favorable price.