Diamondbacks vs Pirates Prediction 5/6/26 MLB Picks Today

The Pittsburgh Pirates and Arizona Diamondbacks meet Wednesday in MLB action at Chase Field. Here’s a Diamondbacks vs. Pirates Prediction. This article will include a Diamondbacks vs. Pirates Pick.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 19-17 on the year and play the Giants and Rockies next. The Pittsburgh Pirates are batting .248 on the season and have a .336 OBP, and a .387 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 3.85 ERA and a 1.25 WHIP. Nick Gonzales leads the Pittsburgh Pirates with 38 hits and 17 RBI, while Ryan O’Hearn and Oneil Cruz have combined for 74 hits and 52 RBI.

Paul Skenes gets the ball for the Pittsburgh Pirates, and he is 4-2 with a 3.18 ERA and 39 strikeouts this season. Skenes is 2-0 with a 1.00 ERA and 20 strikeouts in his career against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 17-17 on the year and play the Mets and Rangers next. The Arizona Diamondbacks are batting. 248 on the season, have a .308 OBP, and have a .414 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.92 ERA and a 1.38 WHIP. Ildemaro Vargas leads the Arizona Diamondbacks with 40 hits and 22 RBI while Nolan Arenado and Corbin Carroll have combined for 60 hits and 36 RBI.

Michael Soroka gets the ball for the Arizona Diamondbacks, and he is 4-1 with a 4.70 ERA and 36 strikeouts this season. Soroka is 0-0 with a 6.14 ERA and 5 strikeouts in his career against the Pittsburgh Pirates.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won each of their last 11 Wednesday night games as underdogs against NL Central opponents.
• The Pirates have lost four of their last five games as favorites following a loss.
• The Diamondbacks have covered the run line in each of their last 12 Wednesday night games as underdogs against NL Central opponents.
• The Pirates have failed to cover the run line in 10 of their last 11 games as favorites against the Diamondbacks following a loss.
• The Diamondbacks have won the first inning in each of their last six home games against NL Central opponents.
• The Diamondbacks have led after 5 innings in each of their last seven home games against NL Central opponents.
• The Diamondbacks have led after 3 innings in each of their last seven home games against NL Central opponents.

Why the Pittsburgh Pirates will win

• The Pirates have won each of their last five road games following a loss.
• The Diamondbacks have lost each of their last four games following a win.
• The Diamondbacks have failed to cover the run line in eight of their last nine games against the Pirates following a win.
• The Pirates have covered the run line in each of their last five road games following a loss.
• The Pirates have won the first inning in each of their last three games as road favorites against NL West opponents.
• The Pirates have led after 5 innings in 10 of their last 11 games as favorites against NL West opponents.
• The Diamondbacks have trailed after 3 innings in each of their last eight games as underdogs.

Total Runs Facts

• Five of the Pirates’ last six games as favorites have gone OVER the total runs line.
• Four of the Diamondbacks’ last five games as underdogs against the Pirates have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Diamondbacks’ last six games at Chase Field.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Pirates’ last four road games against NL West opponents.

Arizona Diamondbacks Player Prop Facts

• Lourdes Gurriel Jr. has hit a home run in two of the Diamondbacks’ last three games as home underdogs against NL Central opponents.
• Ildemaro Vargas has recorded at least one hit in each of his last 25 appearances in night games.
• Michael Soroka has recorded a win in four of his last five appearances at Chase Field.
• Ildemaro Vargas ranks 1st amongst qualified players for Batting Average (.374) this season.

Pittsburgh Pirates Player Prop Facts

• Oneil Cruz has hit at least one home run in three of the Pirates’ last four games as road favorites.
• Marcell Ozuna has recorded two hits in each of his last five road appearances against the Diamondbacks after playing the previous day.
• Oneil Cruz ranks T5th in the league in Steals (11) this season.

Matchup/League Facts

• The Diamondbacks rank 1st in the league for triples this season (11).
• The Diamondbacks rank 29th in the league for walks this season (94).
• The Pirates rank T1st in the league for home runs allowed this season (28).
• The Pirates rank T2nd in the league for strikeouts this season (334).

Diamondbacks vs Pirates Prediction

We’re getting one of the best pitchers in baseball at a reasonable price. The Diamondbacks also haven’t had much success lately stringing wins together. Skenes has a 1.89 ERA in his last 33.1 innings along with 38 strikeouts and just five walks. Soroka has been much more hittable with his 4.70 ERA and 1.43 WHIP on the season. Soroka just allowed 10 hits and 8 runs in 3 innings against the Brewers. Soroka has also walked at least two in three of his last five games. Give me the Pirates with their ace on the hill.