Diamondbacks vs Reds Prediction 8/21/26 MLB Picks Today

The Cincinnati Reds and Arizona Diamondbacks meet Friday in MLB action at Chase Field. Here’s a Diamondbacks vs Reds Prediction. This article will include a Diamondbacks vs Reds Pick.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 61-67 on the year and play the Cubs and Giants next. The Cincinnati Reds are batting .226 on the season, have a .305 OBP, and have a .390 slugging percentage. The Cincinnati Reds’ pitching staff has a 4.47 ERA and a 1.40 WHIP. Sal Stewart leads the Cincinnati Reds with 126 hits and 96 RBI, while Elly De La Cruz and Spencer Steer have combined for 192 hits and 97 RBI.

Nick Lodolo gets the ball for the Cincinnati Reds, and he is 3-2 with a 4.52 ERA and 57 strikeouts this season. Lodolo is 0-0 with a 3.97 ERA and 9 strikeouts in his career against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 67-61 on the year and play the Cubs and Giants next. The Arizona Diamondbacks are batting .243 on the season and have a .316 OBP and a .398 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.18 ERA and a 1.29 WHIP. Ketel Marte leads the Arizona Diamondbacks with 117 hits and 67 RBI, while Corbin Carroll and Geraldo Perdomo have combined for 223 hits and 119 RBI.

Eduardo Rodriguez gets the ball for the Arizona Diamondbacks, and he is 12-4 with a 2.71 ERA and 106 strikeouts this season. Rodriguez is 1-1 with a 3.05 ERA and 17 strikeouts in his career against the Cincinnati Reds.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won seven of their last eight games against the Reds after going to extra innings.
• The Reds have lost four of their last five road games against National League opponents.
• The Diamondbacks have covered the run line in each of their last eight games against National League opponents after going to extra innings.
• The Reds have failed to cover the run line in seven of their last eight night games against National League opponents.
• The Diamondbacks have won the first inning in each of their last four home games.
• The Reds have trailed after 3 innings in each of their last eight games at Chase Field.
• The Reds have trailed after 5 innings in each of their last six road night games.

Why the Cincinnati Reds will win

• The Reds have won each of their last seven night games following a home loss.
• The Diamondbacks have lost five of their last six games as favorites against NL Central opponents following a road win.
• The underdogs have covered the run line in 13 of the last 14 games between the Reds and Diamondbacks.
• The Diamondbacks have failed to cover the run line in each of their last six games as favorites against the Reds following a win.
• The Reds have won the first inning in three of their last four games against NL West opponents.
• The Diamondbacks have trailed after 3 innings in each of their last four games.
• The Diamondbacks have trailed after 5 innings in four of their last five games against NL Central opponents that held a losing record.

Total Runs Facts

• Seven of the Reds’ last eight road games against NL West opponents have gone OVER the total runs line.
• Each of the last four games between the Reds and Diamondbacks have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in each of the Reds’ last five games against NL West opponents.
• There has been at least one run scored in the first inning in each of the Diamondbacks’ last four home games.

Arizona Diamondbacks Player Prop Facts

• Corbin Carroll has hit a home run in three of the Diamondbacks’ last four games against opponents that held a losing record.
• Eduardo Rodriguez has recorded a win in four of his last five appearances.
• Gabriel Moreno has recorded at least one hit in each of the Diamondbacks’ last 13 games.
• Gabriel Moreno ranks 7th amongst qualified players for Batting Average (.307) this season.

Cincinnati Reds Player Prop Facts

• Eugenio Suarez has hit a home run in three of his last four appearances with his team as a road underdog against NL West opponents.
• Nick Lodolo has recorded five or more strikeouts in seven of his eight previous Friday appearances.
• Sal Stewart has recorded at least one hit in each of the Reds’ last 11 road games against NL opponents that held a winning record.

Matchup/League Facts

• The Diamondbacks rank 1st in the league for triples this season (33).
• The Diamondbacks rank 2nd in the league for strikeouts against this season (936).
• The Reds rank 30th in the league for hits this season (958).
• The Reds rank 30th in the league for batting average this season (.226).

Diamondbacks vs Reds Prediction

The Reds still have issues stringing wins together, and Lodolo hasn’t been great with his 4.52 ERA and 1.42 WHIP. The Diamondbacks are chasing down a playoff spot, and Rodriguez is an All-Star with a 2.71 ERA and 1.21 WHIP. At home, Rodriguez has a 2.85 ERA and a .228 allowed batting average in 82 innings. The Diamondbacks can’t blow games like this at home if they’re going to sneak into the wild card. Must-win spot. Give me the Diamondbacks and the reasonable price.