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Diamondbacks vs Rockies Prediction 5/16/26 MLB Picks Today

Arizona Diamondbacks (21-22) vs. Colorado Rockies (17-28)
May 16, 2026 3:10 pm EDT
The Line: Colorado Rockies 119 / Arizona Diamondbacks -143; Over/Under: 11.5
(Get latest betting odds)

In this article, we will formulate a Diamondbacks vs Rockies Prediction for this MLB matchup on Saturday, May 16th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Colorado Rockies Preview

The Colorado Rockies have a 17-28 record this season and are sitting in the fifth place of the NL West. They have an 8-12 home record and are coming off a 1-9 loss at home against the Diamondbacks. They will face the Rangers and the Diamondbacks next.


The Rockies have a .245 batting average this season, .313 OBP and .395 Slugging percentage. Colorado’s pitching staff has a 4.93 ERA and 1.44 WHIP. Troy Johnston is the team’s best hitter with a .318 batting average. Mickey Moniak leads the team in RBI with 26, also adding a team‑high 12 home runs.

Tomoyuki Sugano (R) is the projected starting pitcher for the Rockies, and he has a 3-3 record, 4.07 ERA and 1.19 WHIP.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 21-22 record this season and are sitting in the third place of the NL West. They have a 9-13 away record and are coming off a 9-1 win on the road against the Rockies. They will face the Giants and the Rockies next.

The Diamondbacks have a .237 batting average this season, .302 OBP and .388 Slugging percentage. Arizona’s pitching staff has a 4.42 ERA and 1.27 WHIP. Ildemaro Vargas is the team’s best hitter with a .347 batting average, also leading the team in RBI with 30. He adds a team‑high 7 home runs.

Eduardo Rodriguez (L) is the projected starting pitcher for the Diamondbacks, and he has a 4-0 record, 2.25 ERA and 1.21 WHIP.

Arizona Diamondbacks @ Colorado Rockies Betting Trends: May 16, 2026

 

  • Probable Starting Pitcher: Tomoyuki Sugano      Record this season: 3-3      ERA: 4.07
  • Home Record: 2-2
  • Last 5 against Diamondbacks: –

Why the Colorado Rockies will win

  • The Diamondbacks have lost seven of their last eight games as road favorites after playing the previous day.
  • The Rockies have won three of their last four games as underdogs against the Diamondbacks.
  • The Diamondbacks have failed to cover the run line in each of their last 11 Saturday day games as favorites against National League opponents.
  • The Rockies have covered the run line in each of their last six Saturday day home games against NL West opponents.
  • The Diamondbacks have trailed after 5 innings in each of their last five road day games.
  • The Diamondbacks have trailed after 3 innings in each of their last four road day games.

 

  • Probable Starting Pitcher: Eduardo Rodriguez      Record this season: 4-0      ERA: 2.25
  • Road Record: 1-0
  • Last 5 against Rockies: 3-0

Why the Arizona Diamondbacks will win

  • The Rockies have lost each of their last seven day games against NL West opponents following a loss.
  • The Diamondbacks have won each of their last three games against National League opponents.
  • The Rockies have failed to cover the run line in seven of their last eight home games.
  • The Diamondbacks have covered the run line in eight of their last nine games against National League opponents following a road win.
  • The Rockies have trailed after 3 innings in each of their last six games.
  • The Rockies have lost the first inning in four of their last five games.
  • The Rockies have trailed after 5 innings in each of their last 10 Saturday games against National League opponents that held a losing record.

Total Runs Facts

  • Each of the Diamondbacks’ last six games against National League opponents have gone UNDER the total runs line.
  • Six of the last seven games between the Diamondbacks and Rockies at Coors Field have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Rockies’ last nine day games against NL West opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in five of Eduardo Rodriguez’s last six road appearances as a starter.

Colorado Rockies Player Prop Facts

  • Hunter Goodman has hit a home run in each of his last two appearances against NL West opponents.
  • Brenton Doyle has recorded two or more hits in each of the Rockies’ last three day games against NL West opponents that held a losing record.
  • Mickey Moniak ranks 2nd amongst qualified players for Slugging Percentage (.672) this season.

Arizona Diamondbacks Player Prop Facts

  • Corbin Carroll has hit at least one home run in four of his last 10 appearances with the Diamondbacks as road favorites against NL West opponents.
  • Gabriel Moreno has recorded two or more hits in each of his last six appearances against the Rockies.
  • Eduardo Rodriguez has recorded a win in each of his four previous road appearances against NL West opponents that held a losing record.
  • Ildemaro Vargas ranks 1st amongst qualified players for Batting Average (.347) this season.

Matchup/League Facts

  • The Rockies rank 30th in the league for opponent batting average this season (.272).
  • The Rockies rank 29th in the league for strikeouts against this season (426).
  • The Diamondbacks rank 1st in the league for triples this season (12).
  • The Diamondbacks rank 30th in the league for strikeouts this season (318).

Diamondbacks vs Rockies Prediction

The Rockies are 3-1 in their last 4 meetings against the Diamondbacks and are 3-1 in their last 4 meetings in Colorado.

In this Diamondbacks vs Rockies Prediction, the Diamondbacks are coming as -140 road favorites. The Rockies have been struggling lately and have the pitching disadvantage today with Sugano on the mound, who has given up 9 runs in his last two starts. On the flip side, Rodriguez has given up just one run in his last two starts, the Dbacks have a better offense an the Rockies are struggling against lefties, so I like the Dbacks to win on the road in this one.

Nikos Lagouretos's Free Pick: Arizona Diamondbacks ML

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