Dodgers vs Giants Prediction 9/18/25 MLB Picks Today

The San Francisco Giants and Los Angeles Dodgers meet Thursday in MLB action at Dodger Stadium. Here’s a Dodgers vs Giants Prediction. This article will include a Dodgers vs Giants Pick.

San Francisco Giants Betting Preview

The San Francisco Giants are 76-76 on the year and play the Cardinals and Rockies next. The San Francisco Giants are batting .236 on the season, have a .311 OBP, and a .387 slugging percentage. The San Francisco Giants pitching staff has a 3.84 ERA and a 1.31 WHIP. Heliot Ramos leads the San Francisco Giants with 149 hits and 61 RBI, while Jung Hoo Lee and Willy Adames have combined for 265 hits and 134 RBI.

Logan Webb gets the ball for the San Francisco Giants, and he is 14-10 with a 3.34 ERA and 206 strikeouts this season. Webb is 6-7 with a 4.69 ERA and 86 strikeouts in his career against the Los Angeles Dodgers.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 85-67 on the year and play the Diamondbacks and Mariners next. The Los Angeles Dodgers are batting .254 on the season, have a .330 OBP, and a .440 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.05 ERA and a 1.27 WHIP. Sohei Ohtani leads the Los Angeles Dodgers with 162 hits and 95 RBI while Freddie Freeman and Andy Pages have combined for 306 hits and 164 RBI.

Yoshinobu Yamamoto gets the ball for the Los Angeles Dodgers, and he is 11-8 with a 2.66 ERA and 187 strikeouts this season. Yamamoto is 0-1 with a 3.70 ERA and 27 strikeouts in his career against the San Francisco Giants.

San Francisco Giants @ Los Angeles Dodgers Betting Trends: September 18, 2025

• Probable Starting Pitcher: Yoshinobu Yamamoto      Record this season: 11-8      ERA: 2.66
• Home Record: 3-4
• Last 5 against Giants: 0-1

Why the Los Angeles Dodgers will win

• The Giants have lost each of their last nine games against the Dodgers following a win.
• The Dodgers have won seven of their last eight home games against the Giants following a home win.
• The Giants have failed to cover the run line each of their last 10 Thursday games against teams that held a winning record.
• The Dodgers have covered the run line in five of their last six games against NL West opponents.
• The Dodgers have led after 3 innings in four of their last five home games.
• The Dodgers have led after 5 innings in seven of their last eight games.
• The Giants have lost the first inning in three of their last four night games at Dodger Stadium.

• Probable Starting Pitcher: Logan Webb      Record this season: 14-10      ERA: 3.34
• Road Record: 7-6
• Last 5 against Dodgers: 2-1

Why the San Francisco Giants will win

• The Giants have won each of their last four games as underdogs against National League opponents following a win.
• The Dodgers have lost each of their last five Thursday night games as favorites against NL West opponents.
• The Giants have covered the run line in seven of their last eight games as road underdogs.
• The Dodgers have failed to cover the run line in six of their last seven home games against the Giants following a win.
• The Giants have won the first inning in each of their last four night games against opponents that held a winning record.
• The Giants have led after 3 innings in each of their last five night games against opponents that held a winning record.

Total Runs Facts

• Five of the Dodgers’ last six games after playing the previous day have gone OVER the total runs line.
• Nine of the Giants’ last 11 night games after playing the previous day have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Dodgers’ last nine night games at Dodger Stadium.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Giants’ last five night games.

Los Angeles Dodgers Player Prop Facts

• Shohei Ohtani has hit a home run in three of the Dodgers’ last four night games.
• Andy Pages has recorded at least one hit in each of his last 10 home appearances after playing the previous day.
• Freddie Freeman has recorded a Double in four of the Dodgers’ last five games against the Giants.
• Shohei Ohtani ranks 2nd amongst qualified players for Slugging Percentage (.611) this season.

San Francisco Giants Player Prop Facts

• Casey Schmitt has hit a home run in two of the Giants’ last three road games against the Dodgers.
• Logan Webb has recorded seven strikeouts in three of his last four appearances.
• Dominic Smith has recorded a Double in three of his last four road appearances against the Dodgers.
• Dominic Smith has recorded at least one hit in 20 of his last 22 appearances in night games.
• Logan Webb has recorded a win in each of his last four appearances with the Giants as underdogs.
• Logan Webb ranks 4th in the league for total Strikeouts (206) this season.

Matchup/League Facts

• The Dodgers rank 2nd in the league for runs scored this season (773).
• The Dodgers rank 2nd in the league for home runs this season (223).
• The Giants rank 1st in the league for home runs allowed this season (129).
• The Giants rank 29th in the league for steals this season (65).

Dodgers vs Giants Prediction

As I’ve said many times before, the Dodgers are going to be favored because they’re the Dodgers. It doesn’t hurt being at home and having Yamamoto on the mound. I get it. However, the Giants are in must-win mode if they’re going to sneak into the wild card. We’re getting that desperation on top of their ace in Webb on the bump. Webb was just tagged by the Dodgers, but he’s a back-to-back all-star with a 3.34 ERA and 1.26 WHIP, and the Giants have won 6 of his last 8 starts. The Giants need this game and that creates value in the plus money. Give me the Giants.