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Dodgers vs Nationals Prediction 6/21/25 MLB Picks Today

Washington Nationals (31-45) vs. LA Dodgers (47-30)
June 21, 2025 10:10 pm EDT
The Line: LA Dodgers -269 / Washington Nationals 214; Over/Under: 9
(Get latest betting odds)

In this article, we will formulate a Dodgers vs Nationals prediction for this MLB game on Saturday, June 21, at Dodger Stadium in Los Angeles, California. Let’s take a look at the prediction for this MLB matchup.

Washington Nationals Betting Preview

The Washington Nationals (31-45, 15-21 Away) snapped an 11-game losing skid with a win over the Colorado Rockies in Game 4 of the series, but still lost that series. Prior to it, the Nats were swept by the Mets and Marlins, while in the current series against the Dodgers, they opened with a 6-5 defeat on Friday. Luis Garcia Jr. led the offense with two RBI, while MacKenzie Gore took the loss after allowing six runs (five earned) on seven hits with four strikeouts and four walks in 5.2 innings.


This season, the Nationals average 4.14 runs per game (21st in the MLB) on a .239/.306/.385 triple-slash. When it comes to pitching, the Nationals’ staff has a 4.92 ERA (28th) and 1.38 WHIP (24th). James Wood leads the Nationals with a .279 batting average, 20 home runs, and 56 RBI this season.

Jake Irvin will take the mound for the Nationals on Saturday. The 28-year-old right-hander has a 5-3 record in 15 starts this year with a 4.23 ERA and 1.23 WHIP in 89.1 innings.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers (47-30, 29-13 Home) won three straight series and were on a five-game winning streak before losing to the San Diego Padres on Thursday. The Dodgers opened the current series against the Washington Nationals with a 6-5 victory last night. Miguel Rojas led the offense with two RBI, while Clayton Kershaw got the win after allowing two runs on five hits with four strikeouts and two walks across 5.0 innings of work.

This year, the Dodgers average 5.53 runs per game (1st in the MLB) on a .264/.341/.457 triple-slash. When it comes to pitching, the Dodgers’ staff has a 4.19 ERA (21st) and 1.31 WHIP (20th). Andy Pages leads the Dodgers with a .293 batting average, 15 home runs, and 51 RBI this season.

The projected starting pitcher for the Dodgers is Dustin May, who is 4-4 in 13 starts this season, with a 4.46 ERA and 1.33 WHIP in 72.2 innings.

Total Runs Facts

  • Each of the last four games between the Nationals and Dodgers have gone OVER the total runs line.
  • Five of the Nationals’ last six games as underdogs against the Dodgers have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Nationals’ last seven games as road underdogs.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Dodgers’ last five night games against NL East opponents.

Matchup/League Facts

  • The Dodgers rank 1st in the league for home runs this season (117).
  • The Dodgers rank 1st in the league for RBIs this season (408).
  • The Nationals rank 26th in the league for hits allowed this season (675).
  • The Nationals rank T26th in the league for runs allowed this season (386).

Dodgers vs Nationals Prediction

The Dodgers won six of the previous ten H2H encounters, including five of the last seven. This season, each team recorded two wins in H2H duels. All four went Over, and I am going with another Over in this one. Jake Irvin allowed 3+ runs in each of his last four starts, surrendering 16 runs in total. Dustin May, on the other hand, allowed multiple runs in nine of his previous ten starts, and I am backing the Nats to score 2+ off of him early on. Of course, I believe the Dodgers will trouble Irvin in the opening five innings and score 3+ runs. Back the Over.

Oliver Zivic's Free Pick: Over 8.5

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Oliver Zivic

Professional journalist and expert bettor with 20+ years of experience. I cover Football (soccer), NFL, NBA, NHL, MLB, CFB, and CBB.

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