
Dodgers vs Padres Prediction 6/16/25 MLB Picks Today
San Diego Padres (39-31) vs. LA Dodgers (43-29)
June 16, 2025 10:10 pm EDT
The Line: LA Dodgers -157 / San Diego Padres 128; Over/Under: 9
(Get latest betting odds)
The San Diego Padres and Los Angeles Dodgers meet Monday in MLB action at Dodger Stadium. Here’s a Dodgers vs Padres Prediction. This article will include a Dodgers vs Padres Pick.
San Diego Padres Betting Preview
The San Diego Padres are 39-31 on the year and play the Royals, Nationals, and Reds next. The San Diego Padres are batting .249 on the season, have a .316 OBP, and a .378 slugging percentage. The San Diego Padres pitching staff has a 3.51 ERA and a 1.21 WHIP. Manny Machado leads the San Diego Padres with 84 hits and 43 RBI, while Fernando Tatis Jr. and Luis Arraez have combined for 144 hits and 57 RBI.
Dylan Cease gets the ball for the San Diego Padres, and he is 2-5 with a 4.28 ERA and 96 strikeouts this season. Cease is 2-1 with a 1.95 ERA and 39 strikeouts in his career against the Los Angeles Dodgers.
Los Angeles Dodgers Betting Preview
The Los Angeles Dodgers are 43-29 on the year and play the Nationals, Rockies, and Royals next. The Los Angeles Dodgers are batting .264 on the season, have a .340 OBP, and a .459 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.19 ERA and a 1.32 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 83 hits and 41 RBI, while Freddie Freeman and Andy Pages have combined for 148 hits and 87 RBI.
Shohei Ohtani gets the ball for the Los Angeles Dodgers, and he was 10-5 with a 3.14 ERA and 167 strikeouts in the 2023 season. This will be Ohtani’s second career game against the San Diego Padres.
Why the Los Angeles Dodgers will win
- The Padres have lost seven of their last eight night games against the Dodgers at Dodger Stadium following a road win.
- The Dodgers have won eight of their last nine home games against National League opponents following a home win.
- The Padres have failed to cover the run line in four of their last five games against the Dodgers following a win.
- The Dodgers have covered the run line in three of their last four home games against the Padres.
- The Dodgers have led after 3 innings in each of their last five Monday night games against the Padres at Dodger Stadium.
- The Padres have trailed after 5 innings in four of their last five games as road underdogs against NL West opponents.
Why the San Diego Padres will win
- The Padres have won each of their last nine Monday night games as road underdogs against NL West opponents.
- The Dodgers have lost each of their last five games as favorites against the Padres following a home win.
- The Padres have covered the run line in each of their last nine games as road underdogs after playing the previous day.
- The Dodgers have failed to cover the run line in each of their last seven games against National League opponents following a win.
- The Dodgers have trailed after 3 innings in five of their last six night games against opponents that held a winning record.
- The Dodgers have trailed after 5 innings in six of their last seven home night games.
Los Angeles Dodgers Player Prop Facts
- Teoscar Hernandez has hit a home run in three of the Dodgers’ last four games as favorites.
- Andy Pages has recorded at least one RBI in eight of the Dodgers’ last 10 home games against opponents that held a winning record.
- Shohei Ohtani has scored at least one run in each of the Dodgers’ last 12 Monday night games.
- Shohei Ohtani has recorded two or more strikeouts in each of his last 62 appearances with his team as a favorite.
- Esteury Ruiz has recorded at least one hit in each of his last eight appearances against NL opponents that held a winning record.
- Shohei Ohtani ranks 2nd amongst qualified players for Slugging Percentage (.642) this season.
San Diego Padres Player Prop Facts
- Fernando Tatis Jr. has recorded a Double in three of the Padres’ last four games as road underdogs against the Dodgers.
- Manny Machado has hit a home run in three of the Padres’ last six road games against opponents that held a winning record.
- Xander Bogaerts has recorded at least one RBI in five of the Padres’ last six road games against the Dodgers.
- Dylan Cease has recorded seven or more strikeouts in each of his last four appearances with the Padres as underdogs.
- Fernando Tatis Jr. has scored at least one run in each of the Padres’ last four night games against NL West opponents that held a winning record.
- Manny Machado has recorded at least one hit in each of the Padres’ last nine road games.
- Manny Machado ranks 5th in the league in Hits (84) this season.
Dodgers vs Padres Prediction
The Padres and the plus money is worth a look because they’re a talented group that has a chance every night. The problem is, Cease has been rough in 36.2 road innings, posting a 5.65 ERA and .246 allowed batting average. Ohtani hasn’t pitched in a couple of years, and he’s only expected to pitch an inning or two, but just him taking the mound is going to bring energy to the team and the Dodgers fans. This price is fairly cheap for the Dodgers at home, as you’re often laying closer to -200. I’ll side with the Dodgers on Monday night.