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Dodgers vs Padres Prediction 6/18/25 MLB Picks Today

San Diego Padres (39-33) vs. LA Dodgers (45-29)
June 18, 2025 10:10 pm EDT
The Line: LA Dodgers -187 / San Diego Padres 152; Over/Under: 9.5
(Get latest betting odds)

The San Diego Padres and Los Angeles Dodgers meet Wednesday in MLB action at Dodger Stadium. Here’s a Dodgers vs Padres Prediction. This article will include a Dodgers vs Padres Pick.

San Diego Padres Betting Preview

The San Diego Padres are 39-33 on the year and play the Royals, Nationals, and Reds next. The San Diego Padres are batting .248 on the season, have a .316 OBP, and a .378 slugging percentage. The San Diego Padres pitching staff has a 3.60 ERA and a 1.22 WHIP. Manny Machado leads the San Diego Padres with 86 hits and 45 RBI, while Fernando Tatis Jr. and Luis Arraez have combined for 150 hits and 58 RBI.

Stephen Kolek gets the ball for the San Diego Padres, and he is 3-2 with a 3.50 ERA and 34 strikeouts this season. Kolek is 0-0 with a 4.91 ERA and 2 strikeouts in his career against the Los Angeles Dodgers.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 45-29 on the year and play the Nationals, Rockies, and Royals next. The Los Angeles Dodgers are batting .265 on the season, have a .341 OBP, and a .460 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.19 ERA and a 1.32 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 85 hits and 43 RBI, while Freddie Freeman and Andy Pages have combined for 155 hits and 90 RBI.

Emmet Sheehan gets the ball for the Los Angeles Dodgers, and he was 4-1 with a 4.92 ERA and 64 strikeouts in the 2023 season. This will be Sheehan’s first career game against the San Diego Padres.

Why the Los Angeles Dodgers will win

  • The Dodgers have won seven of their last eight games after playing the previous day.
  • The Padres have lost each of their last six Wednesday night road games.
  • The Padres have failed to cover the run line in five of their last six games at Dodger Stadium.
  • The Dodgers have covered the run line in four of their last five games after playing the previous day.
  • The Dodgers have led after 5 innings in three of their last four games against National League opponents that held a winning record.

Why the San Diego Padres will win

  • The Padres have won five of their last six games as underdogs against the Dodgers following a road loss.
  • The Dodgers have lost five of their last seven games as favorites against the Padres following a home win.
  • The Padres have covered the run line in 10 of their last 11 games as underdogs against NL West opponents following a road loss.
  • The Dodgers have failed to cover the run line in seven of their last eight Wednesday night games as favorites against NL West opponents.
  • The Padres have led after 3 innings in four of their last five night games against NL West opponents that held a winning record.
  • The Padres have won the first inning in four of their last five games against opponents that held a winning record at Dodger Stadium.

Los Angeles Dodgers Player Prop Facts

  • Will Smith has hit a home run in four of his last five appearances against the Padres after playing the previous day.
  • Tommy Edman has recorded at least one RBI in five of his last six appearances after playing the previous day.
  • Will Smith has scored at least one run in each of his last seven appearances against opponents that held a winning record.
  • Esteury Ruiz has recorded at least one hit in each of his last eight appearances against NL opponents that held a winning record.
  • Shohei Ohtani ranks 2nd amongst qualified players for Slugging Percentage (.634) this season.

San Diego Padres Player Prop Facts

  • Manny Machado has hit a home run in four of the Padres’ last eight road games against opponents that held a winning record.
  • Manny Machado has recorded at least one RBI in four of the Padres’ last five road games against opponents that held a winning record.
  • Fernando Tatis Jr. has scored at least one run in each of the Padres’ last six night games against NL West opponents that held a winning record.
  • Manny Machado has recorded at least one hit in each of the Padres’ last 11 road games.
  • Manny Machado ranks 5th in the league in Hits (86) this season.

Dodgers vs Padres Prediction

The Padres are in a funk and a hard team to trust right now, but this is a chance for them to get back on track. Kolek has been solid with a 3.50 ERA and 1.32 WHIP, and he’s been sharper this month, allowing 13 hits and four earned runs in 15.2 innings. In 36 road innings, Kolek has a 1.75 ERA and a .227 allowed batting average with 27 strikeouts. Sheehan hasn’t pitched since October 2023 after having Tommy John surgery in 2024. Just 11.1 innings in AAA don’t do much for me. We have no idea what to expect from Kolek. Give me the Padres on Wednesday night in this rivalry MLB game.

Randy Chambers's Free Pick: San Diego Padres +152

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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