FanDuel Best MLB DFS Picks: Giants vs. Padres 4/30/25

Major League Baseball presents FanDuel baseball fans with a National League matchup featuring the San Diego Padres and the San Francisco Giants. Let’s take a look at this MLB game from a DFS perspective.

Before we dive into the San Diego Padres vs. San Francisco Giants game let’s review the rules for the FanDuel single game showdown contest.

FanDuel Single Game Contest Rules

Here are the FanDuel single game contest rules. You have $60,000 to utilize on five players from either team. However, one of those players will be designated as your team MVP. The MVP accumulates 1.5x times the standard FanDuel fantasy points value. Additionally, the MVP is 1.5 times the standard cost of the flex position.

The remaining five players in your lineup will be flex plays. The five flex positions will receive the standard FanDuel points value. Having stated that, it is highly important for you to identify the correct player for your MVP position if you hope to win a large field GPP (guaranteed prize pool) FanDuel single game contest.

If you have additional questions regarding the rules for the single game contest, I highly recommend that you check out the FanDuel website for more details.

*It should be noted that FanDuel does not utilize the pitcher position in single game MLB contests. Having stated that, only batters are available for single game MLB lineups on the FanDuel platform.

Here are my FanDuel picks for this afternoon’s San Francisco Giants vs. San Diego Padres matchup.

FanDuel MLB Player Selections

MVP-Fernando Tatis Jr., Outfielder, San Diego Padres $15,000

On Wednesday afternoon, Major League Baseball presents the final game of a two-game National League series featuring the San Diego Padres and the San Francisco Giants.

How are these two teams playing entering tonight’s MLB game? The San Diego Padres arrive at the second game of this two-game series with the San Francisco Giants playing below average baseball. More specifically, the San Diego Padres have lost four of the team’s last five games played in the 2025 MLB regular season, including a 6-0 shutout loss to the Detroit Tigers last week.

In direct contrast to the San Diego Padres, the San Francisco Giants are currently playing good baseball entering this evening’s game. The Giants have won four of the team’s last six games played in the 2025 MLB regular season, including a 3-2 win over the Texas Rangers three days ago.

Now that we have determined how both of these teams are currently playing let’s shift our attention to this evening’s contest. Outfielder Fernando Tatis Jr. has been an essential part of the San Diego Padres starting lineup this season. With that said, how has the veteran outfielder performed from a statistical standpoint? Let’s examine Tatis Jr.’s relevant game data from the 2025 MLB regular season to answer that question.

In 27 games that San Diego Padres outfielder Fernando Tatis Jr. has played in the 2025 MLB regular season, Tatis Jr. has compiled a rather impressive .346 batting average, 36 hits, eight home runs, 11 walks, 18 RBIs (runs batted in), seven stolen bases and 24 runs scored.

More recently, in the Houston Astros 3-2 win over the San Diego Padres earlier this month, San Diego outfielder Fernando Tatis Jr. played exceptionally well. In the Astros victory over the Padres, Tatis Jr. amassed two hits, one RBI, two runs scored and one home run. It should also be mentioned that in the Astros defeat of the Padres, Tatis Jr. compiled a massive 30.9 FanDuel points.

In my view, Fernando Tatis Jr. is the most likely player to accumulate the most FanDuel points in this MLB game. With that said, I am rolling with San Diego Padres outfielder Fernando Tatis Jr. at the MVP position for this one game MLB DFS slate.

Flex plays I like in this game (FanDuel price noted): Manny Machado, Third Baseman (San Diego Padres) $12,800: LaMonte Wade Jr., First Baseman (San Francisco Giants) $6,200: Willy Adames, Shortstop (San Francisco Giants) $7,600.