Giants vs Astros Prediction 8/10/26 MLB Picks Today
Houston Astros (60-59) vs. San Francisco Giants (49-69)
August 10, 2026 9:45 pm EDT
The Line: San Francisco Giants 135 / Houston Astros -163; Over/Under: 8
(Get latest betting odds)
The Houston Astros and San Francisco Giants meet Monday in MLB action at Oracle Park. Here’s a Giants vs Astros Prediction. This article will include a Giants vs Astros Pick.
Houston Astros Betting Preview
The Houston Astros are 60-59 on the year and play the Angels and Mariners next. The Houston Astros are batting .245 on the season, have a .321 OBP, and have a .415 slugging percentage. The Houston Astros’ pitching staff has a 4.59 ERA and a 1.36 WHIP. Yordan Alvarez leads the Houston Astros with 137 hits and 86 RBI, while Isaac Paredes and Christian Walker have combined for 205 hits and 127 RBI.
Hayden Wesneski gets the ball for the Houston Astros, and he is 2-0 with a 3.86 ERA and 8 strikeouts this season. Wesneski is 0-3 with an 8.83 ERA and 21 strikeouts in his career against the San Francisco Giants.
San Francisco Giants Betting Preview
The San Francisco Giants are 49-69 on the year and play the Rockies and Guardians next. The San Francisco Giants are batting .249 on the season, have a .307 OBP, and have a .409 slugging percentage. The San Francisco Giants’ pitching staff has a 4.37 ERA and a 1.36 WHIP. Jung Hoo Lee leads the San Francisco Giants with 122 hits and 45 RBI, while Rafael Devers and Casey Schmitt have combined for 216 hits and 119 RBI.
Blade Tidwell gets the ball for the San Francisco Giants, and he is 0-0 with a 3.18 ERA and 13 strikeouts this season. This will be Tidwell’s first career game against the Houston Astros.
Why the San Francisco Giants will win
- The Giants have won each of their last five games as underdogs against the Astros.
- The Astros have lost each of their last four games as road favorites against National League opponents.
- The Astros have failed to cover the run line in each of their last seven games as favorites following a road loss.
- The Giants have covered the run line in each of their last six games as home underdogs against AL West opponents.
- The Giants have led after 3 innings in each of their last four games against the Astros.
- The Astros have trailed after 5 innings in each of their last six road games against NL West opponents that held a losing record.
Why the Houston Astros will win
- The Giants have lost eight of their last nine night games against American League opponents that held a winning record.
- The Astros have won seven of their last eight road games against teams that held a losing record.
- The Giants have failed to cover the run line in 12 of their last 13 night games against American League opponents that held a winning record.
- The Astros have covered the run line in 10 of their last 12 road games following a road loss.
- The Giants have trailed after 5 innings in five of their last six night games against American League opponents that held a winning record.
- The Astros have led after 3 innings in seven of their last eight night games against National League opponents that held a losing record.
Total Runs Facts
- Five of the Astros’ last six games as favorites have gone OVER the total runs line.
- Five of the Giants’ last six games following an extra innings loss have gone UNDER the total runs line.
- There has been no run scored during the first inning in each of the Astros’ last six night games.
- There has been no run scored during the first inning in seven of the Giants’ last eight games as home underdogs against AL West opponents.
San Francisco Giants Player Prop Facts
- Osleivis Basabe has hit a home run in each of the Giants’ last two games against opponents that held a winning record.
- Willy Adames has recorded a hit in each of the Giants’ last eight home games.
- Jung Hoo Lee ranks 10th amongst qualified players for Batting Average (.298) this season.
Houston Astros Player Prop Facts
- Jeremy Pena has hit a home run in each of the Astros’ last three games as favorites against NL opponents.
- Hayden Wesneski has recorded four or more strikeouts in eight of his last 10 appearances in night games.
- Christian Walker has recorded at least one hit in each of the Astros’ last 14 road games against NL opponents that held a losing record.
- Hayden Wesneski has recorded a win in three of his last four appearances with the Astros as favorites.
- Yordan Alvarez ranks T1st in the league in Home Runs (35) this season.
Matchup/League Facts
- The Giants rank 30th in the league for walks this season (309).
- The Giants rank 1st in the league for home runs allowed this season (112).
- The Astros rank 29th in the league for steals this season (38).
- The Astros rank 29th in the league for walks allowed this season (494).
Giants vs Astros Prediction
These pitchers have a combined 28.2 innings under their belt this season, so I’m not thrilled with this matchup. However, somebody has to win, and I’ll roll the dice with the Astros who still somehow are in the driver’s seat for a division title. The Giants have nothing to play for at this stage of the season, and they often look like it. To close the gap on the AL West, the Astros need to take advantage of these games. The price isn’t too ridiculous. Give me the Astros on Monday night.