Giants vs Mariners Prediction 4/4/25 MLB Picks Today

In this article, we will formulate a Giants vs Mariners prediction for this MLB game on Friday, April 4, at Oracle Park in San Francisco, California. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Betting Preview

The Seattle Mariners (3-4, 0-0 Away) split a four-game series with the Athletics and then lost a three-game series to the Detroit Tigers. The Mariners were in jeopardy of being swept by the Tigers after losing the first two games, but they edged them out 3-2 to close out the series. Victor Robles had two RBI to lead Seattle offensively, while Luis Castillo got a win after allowing two runs on five hits with five strikeouts and two walks in 7.0 innings.

This season, the Mariners average 2.57 runs per game (26th in the MLB) on a .172/.285/.309 slash line. Regarding pitching, the Mariners’ staff has a 4.00 ERA (16th) and 1.27 WHIP (18th). Jorge Polanco leads the Mariners with a .400 batting average, one home run, and four RBI this season.

The projected starting pitcher for the Mariners is Luis F. Castillo, in what should be a bullpen day for Seattle. He last pitched in 2022 and was called from the minors to open this game against the Giants.

San Francisco Giants Betting Preview

The San Francisco Giants (5-1, 0-0 Home) won two of three games to beat the Cincinnati Reds in the opening series of the season and then shocked the Houston Astros by sweeping them in a three-game series. The Giants were great defensively, as they limited the Astros to six runs in three games. Heliot Ramos and Wilmer Flores hit a pair of RBI apiece in the latest 6-3 victory, while Landen Roupp pitched for 4.0 innings, allowing three runs on four hits with eight strikeouts and four walks. Randy Rodriguez was credited with a win.

This year, the Giants average 5.00 runs per game (9th in the MLB) on a .202/.273/.399 triple-slash. When it comes to pitching, the Giants’ staff has a 2.72 ERA (5th) and 1.00 WHIP (5th). Wilmer Flores leads the Giants with a .227 batting average, four home runs, and ten RBI this season.

Justin Verlander will take the mound for the Gaints on Friday. The 42-year-old righty had a 5-6 record last season in nine starts with a 5.48 ERA and 1.38 WHIP in 90.1 innings for the Houston Astros. This season, Verlander pitched for 5.0 innings with a 3.60 ERA in a no-decision against the Reds.

Why the Giants will beat the Mariners

• The Giants have won eight of their last nine games against American League opponents.
• The Mariners have lost four of their last five games against NL West opponents following a win.
• The Giants have covered the run line in each of their last six games.
• The Mariners have failed to cover the run line in each of their last four games as road underdogs against National League opponents.
• The Mariners have trailed after 5 innings in four of their last five road openers.
• The Mariners have trailed after 3 innings in three of their last four road openers.

Total Runs Facts

• Six of the Giants’ last seven games as favorites against AL West opponents have gone UNDER the total runs line.
• Four of the Mariners’ last five games have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Mariners’ last five day games against National League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the last seven day games between the Mariners and Giants.

Giants vs Mariners Prediction

The Mariners won six of the previous ten H2H encounters, including five of the last seven. I don’t like it when the teams are on a bullpen day, and I usually bet against them on such occasions. Well, that occasion is today with the Mariners, who will start a guy who hasn’t pitched in the majors since 2022. Even then, Castillo pitched for 3.2 innings, and that’s his whole experience in the MLB. I know the Mariners will use multiple pitchers, but the Giants are going to trouble Castillo early on. Verlander, on the other hand, allows a .174 BA in 132 at-bats against the Mariners in his career. I am backing the Giants to win.