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Giants vs Mets Prediction 4/5/26 MLB Picks Today

NY Mets (5-4) vs. San Francisco Giants (3-6)
April 5, 2026 4:05 pm EDT
The Line: San Francisco Giants -120 / NY Mets 100; Over/Under: 7
(Get latest betting odds)

The New York Mets and San Francisco Giants meet Sunday in MLB action at Oracle Park. Here’s a Giants vs. Mets Prediction. This article will include a Giants vs. Mets Pick.

New York Mets Betting Preview

The New York Mets are 5-4 on the year and play the Diamondbacks and Athletics next. The New York Mets are batting. 239 on the season, have a .328 OBP, and have a .384 slugging percentage. The New York Mets pitching staff has a 2.58 ERA and a 1.17 WHIP. Juan Soto leads the New York Mets with 11 hits and 5 RBI, while Mark Vientos and Bo Bichette have combined for 17 hits and 9 RBI.

Kodai Senga gets the ball for the New York Mets, and he is 0-1 with a 3.00 ERA and 9 strikeouts this season. Senga is 1-0 with a 7.07 ERA and 11 strikeouts in his career against the San Francisco Giants.

San Francisco Giants Betting Preview

The San Francisco Giants are 3-6 on the year and play the Phillies and Orioles next. The San Francisco Giants are batting. 206 on the season, have a .269 OBP, and have a .296 slugging percentage. The San Francisco Giants pitching staff has a 4.61 ERA and a 1.33 WHIP. Luis Arraez leads the San Francisco Giants with 10 hits and 3 RBI while Rafael Devers and Matt Chapman have combined for 14 hits and 4 RBI.

Logan Webb gets the ball for the San Francisco Giants, and he is 1-1 with a 7.36 ERA and 12 strikeouts this season. Webb is 3-2 with a 3.21 ERA and 39 strikeouts in his career against the New York Mets.

Why the San Francisco Giants will win

  • The Mets have lost each of their last eight Sunday games against National League opponents.
  • The Giants have won four of their last five day games against National League opponents.
  • The Mets have failed to cover the run line in seven of their last eight day games following a win.
  • The Giants have covered the run line in seven of their last eight Sunday games against NL East opponents that held a winning record.
  • The Giants have led after 5 innings in five of their last six games as favorites.
  • The Giants have won the first inning in four of their last five home games against National League opponents that held a winning record.
  • The Giants have led after 3 innings in five of their last six games as favorites.

Why the New York Mets will win

  • The Giants have lost each of their last nine games as favorites against National League opponents following a home loss.
  • The Mets have won each of their last four games as underdogs against the Giants.
  • The Giants have failed to cover the run line in each of their last 13 games as favorites against National League opponents following a home loss.
  • The Mets have covered the run line in each of their last 10 road games against NL West opponents following a win.
  • The Giants have trailed after 5 innings in four of their last five games against NL East opponents.
  • The Mets have won the first inning in each of their last three day games against NL West opponents.
  • The Mets have led after 3 innings in eight of their last 10 road games against NL West opponents that held a losing record.

Total Runs Facts

  • Each of the Mets’ last 11 day games after playing the previous day has gone UNDER the total runs line.
  • Each of the last five games between the Mets and Giants has gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Giants’ last 10 games as favorites.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Mets’ last eight games against NL West opponents.

San Francisco Giants Player Prop Facts

  • Rafael Devers has hit a home run in four of the Giants’ last seven games against NL East opponents.
  • Luis Arraez has recorded two or more hits in four of his last five appearances with his team as a home favorite against NL East opponents.
  • Logan Webb has recorded seven or more strikeouts in each of his last four appearances in day games.
  • Logan Webb has recorded a win in three of his four previous appearances in day games against NL East teams that held a winning record.

New York Mets Player Prop Facts

  • Kodai Senga has recorded six or more strikeouts in six of his eight previous appearances in day games against NL teams that held a losing record.
  • Juan Soto has recorded at least one hit in each of his last 11 appearances with the Mets as underdogs against NL opponents.
  • Kodai Senga has recorded a win in four of his last five appearances in day games against teams that held a losing record.
  • Juan Soto has hit a home run in six of his last 10 appearances with the Mets as road underdogs.
  • Francisco Alvarez ranks T4th in the league in Home Runs (3) this season.

Matchup/League Facts

  • The Giants rank 29th in the league for home runs this season (4).
  • The Giants rank 29th in the league for RBIs this season (22).
  • The Mets rank T1st in the league for triples this season (3).
  • The Mets rank T2nd in the league for walks this season (40).

Giants vs Mets Prediction

The Giants are a tough sell with how they’re playing out of the gate, but Webb at Oracle has been a safe bet over the years. In 88 career starts at Oracle, Webb has a 2.92 ERA, 1.14 WHIP and 529 strikeouts in 552.1 innings. Senga has been a strong pitcher through three seasons, but the Giants need a feel-good win and they have their ace on the bump at home. This feels like just what the doctor ordered. Give me the Giants and the cheap price on Sunday.

Randy Chambers's Free Pick: San Francisco Giants -120

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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