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Giants vs Yankees Prediction 3/28/26 MLB Picks Today

NY Yankees (2-0) vs. San Francisco Giants (0-2)
March 28, 2026 7:15 pm EDT
The Line: San Francisco Giants 109 / NY Yankees -131; Over/Under: 8
(Get latest betting odds)

In this article we will formulate a Giants vs Yankees prediction for this MLB game on Saturday, March 28th at Oracle Park in San Francisco, California. Let’s take a look at the prediction for this MLB matchup. 

San Francisco Giants Betting Preview

The San Francisco Giants are 0-2 this season after they lost the first two games in this series by scores of 7-0 and 3-0. In game two, San Francisco pitched a very strong game, but they allowed three runs in the sixth for the loss. The Giants recorded just one hit and they were led by Ramos, who went 1-3 in the game. Ray allowed five hits and two earned runs over 5.1 innings for the loss, while Butto allowed two hits and one earned run in relief. 

Last season, San Francisco was 10th in the MLB with a 3.82 ERA, along with a 1.30 WHIP and a .248 opponent batting average. The Giants finished 17th in the MLB with 705 runs with a .235 batting average and a .311 on base percentage. Willy Adames led SF with 30 home runs and 87 RBIs, while Matt Chapman added 21 home runs and 61 RBIs. The projected starting pitcher for the Giants is Tyler Mahle, who went 6-4 with a 2.18 ERA and a 1.13 WHIP over 86.2 innings pitched last season. 

New York Yankees Betting Preview

The New York Yankees are 2-0 this year after they won game two by a score of 3-0 on Friday afternoon. New York generated plenty of hits in the game, but they only managed three runs in the sixth inning for the shutout win. The Yankees recorded eight hits and they were led by Judge, who went 1-4 with one home run and two RBIs in the game. Schlittler allowed one hit and zero earned runs over 5.1 innings for the win, while Bednar got the save. 

Last season, New York had a 3.91 ERA with a 1.25 WHIP and a .229 opponent batting average, while scoring 849 runs with a .251 batting average and a .332 on base percentage. Aaron Judge led the team with 53 home runs and 114 RBIs, while Trent Grisham added 34 home runs and 74 RBIs. The projected starting pitcher for New York is Will Warren, who went 9-8 with a 4.44 ERA and a 1.37 WHIP over 162.1 innings pitched last year. 

Why the San Francisco Giants will win

  • The Yankees have lost six of their last nine games as favorites against NL West opponents following a win.
  • The Giants have won each of their last four day games after playing the previous day.
  • The Yankees have failed to cover the run line in 10 of their last 11 games against NL West opponents following a win.
  • The Giants have covered the run line in five of their last six home games against American League opponents after playing the previous day.
  • The Yankees have trailed after 5 innings in three of their last four road day games.
  • The Yankees have lost the first inning in each of their last five Saturday day games against National League opponents.
  • The Giants have led after 3 innings in four of their last five home games against AL East opponents that held a winning record.

Why the New York Yankees will win

  • The Yankees have won each of their last nine games against teams that held a losing record.
  • The Giants have lost each of their last seven games as home underdogs against AL East opponents.
  • The Yankees have covered the run line in each of their last seven games against National League opponents.
  • The Giants have failed to cover the run line in 13 of their last 14 home games against American League opponents that held a winning record.
  • The Yankees have led after 5 innings in four of their last five games against National League opponents.
  • The Yankees have won the first inning in four of their last five games against opponents that held a losing record.
  • The Yankees have led after 3 innings in four of their last five games against National League opponents.

Total Runs Facts

  • Eight of the Yankees’ last nine day games as favorites have gone UNDER the total runs line.
  • Seven of the Giants’ last eight day games after playing the previous day have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Yankees’ last 10 day games against NL West opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Giants’ last four games as underdogs.

San Francisco Giants Player Prop Facts

  • Rafael Devers has hit a home run in two of his last three appearances against the Yankees after playing the previous day.
  • Tyler Mahle has recorded five or more strikeouts in each of his six previous appearances against AL East opponents that held a winning record.
  • Heliot Ramos has recorded at least one hit in 15 of his last 16 appearances against AL opponents that held a winning record.
  • Tyler Mahle has recorded a win in three of his last four home appearances against AL opponents that held a winning record.
  • Heliot Ramos has recorded a Double in three of the Giants’ last four day games against AL opponents that held a winning record.

New York Yankees Player Prop Facts

  • Aaron Judge has hit at least one home run in four of the Yankees’ last five games against NL West opponents that held a losing record.
  • Giancarlo Stanton has recorded at least one hit in each of his last 13 appearances against the Giants.
  • Paul Goldschmidt has recorded at least one Double in each of his last four appearances against NL opponents.

Giants vs Yankees Prediction 

San Francisco comes into this game looking for their first run of the season, which is never a good sign when you have played two games. The Giants are going against Will Warren, who is very average, so they should find some baserunners here. New York is facing Mahle, who had elite numbers last season in limited action. I think the Giants will finally get some offense here and while I don’t love Mahle, I do like the Giants with plus money. Take San Francisco to win at home. 

David Racey's Free Pick: Giants ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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