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Guardians vs Blue Jays Prediction 6/26/25 MLB Picks Today

Toronto Blue Jays (42-37) vs. Cleveland Guardians (40-38)
June 26, 2025 1:10 pm EDT
The Line: Cleveland Guardians -112 / Toronto Blue Jays -108; Over/Under: 8
(Get latest betting odds)

The Toronto Blue Jays and Cleveland Guardians meet Thursday in MLB action at Progressive Field. Here’s a Guardians vs Blue Jays Prediction. This article will include a Guardians vs Blue Jays Pick.

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 42-37 on the year and play the Red Sox, Yankees, and Angels next. The Toronto Blue Jays are batting .256 on the season, have a .326 OBP, and a .400 slugging percentage. The Toronto Blue Jays’ pitching staff has a 4.20 ERA and a 1.25 WHIP. Bo Bichette leads the Toronto Blue Jays with 93 hits and 48 RBI, while Vladimir Guerrero Jr. and Ernie Clement have combined for 159 hits and 60 RBI.

Kevin Gausman gets the ball for the Toronto Blue Jays, and he is 5-6 with a 4.60 ERA and 84 strikeouts this season. Gausman is 4-5 with a 2.61 ERA and 59 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 40-38 on the year and play the Cardinals, Cubs, and Tigers next. The Cleveland Guardians are batting .231 on the season, have a .302 OBP, and a .373 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.89 ERA and a 1.37 WHIP. Jose Ramirez leads the Cleveland Guardians with 92 hits and 38 RBI, while Steven Kwan and Carlos Santana have combined for 150 hits and 61 RBI.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 4-7 with a 3.86 ERA and 75 strikeouts this season. Bibee is 3-0 with a 2.00 ERA and 14 strikeouts in his career against the Toronto Blue Jays.

Why the Cleveland Guardians will win

  • The Blue Jays have lost seven of their last eight day games after going to extra innings.
  • The Guardians have won each of their last five home games against the Blue Jays after going to extra innings.
  • The Blue Jays have failed to cover the run line each of their last nine Thursday day games against American League opponents that held a winning record.
  • The Guardians have covered the run line in four of their last five day games after going to extra innings.
  • The Guardians have led after 3 innings in each of their last four games as home favorites.
  • The Blue Jays have lost the first inning in three of their last four games as underdogs.
  • The Guardians have led after 5 innings in five of their last six games against the Blue Jays at Progressive Field.

Why the Toronto Blue Jays will win

  • The Guardians have lost three of their last four games as home favorites following a home win.
  • The Blue Jays have won six of their last seven Thursday games as underdogs.
  • The Blue Jays have covered the run line in each of their last 10 games as road underdogs following an extra innings loss.
  • The Guardians have failed to cover the run line in each of their last eight games as favorites following an extra innings win.
  • The Blue Jays have led after 3 innings in three of their last four games against American League opponents that held a winning record.
  • The Guardians have trailed after 5 innings in six of their last seven day games against American League opponents that held a winning record.

Cleveland Guardians Player Prop Facts

  • Jose Ramirez has recorded at least one hit in 35 of his last 36 appearances after playing the previous day.
  • Lane Thomas has hit a home run in each of the Guardians’ last three home games against opponents that held a winning record.
  • Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
  • Jose Ramirez ranks 6th in the league in Hits (92) this season.

Toronto Blue Jays Player Prop Facts

  • Vladimir Guerrero Jr. has hit a home run in three of the Blue Jays’ last four games as road underdogs against the Guardians.
  • Ernie Clement has recorded a Double in five of his last six appearances against former teams.
  • Kevin Gausman has recorded six or more strikeouts in each of his last five Thursday day appearances against teams that held a winning record.
  • George Springer has recorded at least one hit in each of the Blue Jays’ last 14 road games against AL opponents that held a winning record.
  • Kevin Gausman has recorded a win in each of his last three appearances at Progressive Field.
  • Bo Bichette ranks 5th in the league in Hits (93) this season.

Guardians vs Blue Jays Prediction

The Blue Jays have cooled off recently, and Gausman isn’t the pitcher I’m running to the window to back. Gausman has a 4.60 ERA on the year, and he’s allowed 23 hits and 17 runs in his last 20 innings. Gausman is probably excited that the month of June is coming to an end. Bibee has been more trustworthy lately, and he has a 2.50 ERA and .229 allowed batting average in 36 home innings. Quick turnarounds also usually favor the home team. Give me the Guardians and the cheap price.

Randy Chambers's Free Pick: Cleveland Guardians -112

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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