Guardians vs Dodgers Prediction 5/27/25 MLB Picks Today

The Los Angeles Dodgers and the Cleveland Guardians meet Tuesday in MLB action from Progressive Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Guardians vs Dodgers Prediction.

Starting Pitching Matchup

The Los Angeles Dodgers will send out Dustin May for the start here, and May is 2-4 with a 4.09 ERA and 49 strikeouts this season. This will be May’s first career start against the Guardians. Tanner Bibee will get the start for the Guardians here and is 4-4 with a 3.57 ERA and 43 strikeouts this season. This will be Bibee’s first career start against the Guardians.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to build on their 7-2 win over the Guardians in Monday’s series opener to improve to 33-21 on the year. After this series, the Dodgers will head home for a headliner series against the New York Yankees.

Dodgers Win 4 Of Their Last 6 Games

Shohei Ohtani has 62 hits, including 9 doubles, 19 home runs, 33 RBIs, and 4 triples, while Tommy Edman has 31 hits with 8 home runs and 26 RBIs. Michael Conforto has 25 hits with 9 doubles, while Teoscar Hernandez has 47 hits with 10 home runs, 13 doubles, and 42 RBIs as well this season. Ohtani has a team-high 11 stolen bases, while Max Muncy has 8 doubles but also has 50 strikeouts so far this season. Mookie Betts has also chipped in 8 home runs and 31 RBIs on the year. Freddie Freeman has also logged 57 hits with a team-high 14 doubles, 9 home runs, and 35 RBIs.

Why the Los Angeles Dodgers will win

• The Guardians have lost each of their last six games against NL West opponents that held a winning record.
• The Dodgers have won each of their last six games against AL Central opponents.
• The Guardians have failed to cover the run line in each of their last six games as underdogs against NL West opponents.
• The Dodgers have covered the run line in each of their last four night games against AL Central opponents.

Los Angeles Dodgers Player Prop Facts

• Teoscar Hernandez has recorded a Double in four of his last five road appearances.
• Shohei Ohtani has hit a home run in four of the Dodgers’ last five games as road favorites against AL Central opponents.
• Freddie Freeman has recorded at least one RBI in each of his last six road appearances against AL Central opponents that held a winning record.
• Tommy Edman has scored at least one run in each of his last seven appearances in night games against AL teams that held a winning record.
• Dustin May has recorded six or more strikeouts in each of his last three appearances with the Dodgers as favorites.
• Freddie Freeman has recorded at least one Single in each of the Dodgers’ last eight games as road favorites.
• Mookie Betts has recorded at least one hit in each of his last 12 road appearances against AL Central opponents.
• Shohei Ohtani ranks 1st in the league in Home Runs (19) this season.

Cleveland Guardians Recap

The Cleveland Guardians will be out to bounce back from their series-opening loss to the Dodgers in Monday’s matchup to slip to 29-24 on the year. After this series, the Guardians will take on the Los Angeles Angels at home.

Guardians Drop Back-To-Back Games

Steven Kwan leads the Guardians with 65 hits as part of a .314 batting average and 4 home runs, 12 doubles, and 19 RBIs. Kyle Manzardo has 36 hits with 6 doubles, 2 triples, 10 home runs, and a team-high 28 RBIs this year. Gabriel Arias has 9 doubles but also 52 strikeouts, and Manzardo has 52 strikeouts so far this season. Arias has also added 4 home runs and 20 RBIs, and Jose Ramirez has chipped in 9 home runs and 26 RBIs. Carlos Santana has also added 40 hits with 6 home runs and 27 RBIs this season.

Why the Cleveland Guardians will win

• The Dodgers have lost each of their last five games as favorites following a road win.
• The Guardians have won four of their last six games as underdogs.
• The Dodgers have failed to cover the run line in each of their last six games following a road win.
• The Guardians have covered the run line in four of their last five night games against NL West opponents following a home loss.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in two of the Guardians’ last three home games against NL opponents.
• Jose Ramirez has recorded at least one Double in three of the Guardians’ last four games as underdogs against NL West opponents.
• Carlos Santana has recorded at least one RBI in six of his last seven appearances with the Guardians as underdogs.
• Jose Ramirez has scored at least one run in seven of the Guardians’ last eight night games.
• Jose Ramirez has recorded a Single in eight of the Guardians’ last nine games as underdogs against NL opponents.
• Jose Ramirez has recorded at least one hit in each of the Guardians’ last 19 games.
• Steven Kwan ranks T6th in the league in Hits (65) this season.

Total Runs Facts

• Each of the Dodgers’ last four games against AL Central opponents have gone OVER the total runs line.
• Five of the Guardians’ last six night games against National League opponents have gone UNDER the total runs line.

Guardians vs Dodgers Prediction

I’m on the under in this one. I get the case to be made for either side in this game, as these are two decent options in their respective rotations. Bibee hasn’t been one of my favorite options, but he’s been excellent at home this season and has allowed just four runs in 20 innings in his last three home starts. Dustin May has a better arm than a 4.09 ERA, and I think we could have a bit of a pitcher’s duel here. Give me the under.