Guardians vs Rangers Prediction 9/27/25 MLB Picks Today

The Texas Rangers and Cleveland Guardians meet Saturday in MLB action at Progressive Field. Here’s a Guardians vs Rangers Prediction. This article will include a Guardians vs Rangers Pick.

Texas Rangers Betting Preview

The Texas Rangers are 81-79 on the year after playing the Twins. The Texas Rangers are batting .235 on the season, have a .303 OBP, and a .382 slugging percentage. The Texas Rangers pitching staff has a 3.45 ERA and a 1.17 WHIP. Josh Smith leads the Texas Rangers with 124 hits and 35 RBI while Wyatt Langford and Josh Jung have combined for 236 hits and 122 RBI.

Jacob Latz gets the ball for the Texas Rangers, and he is 2-0 with a 2.80 ERA and 70 strikeouts this season. Latz is 0-1 with a 4.91 ERA and 5 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 86-74 on the year after playing the Tigers. The Cleveland Guardians are batting .225 on the season, have a .296 OBP, and a .372 slugging percentage. The Cleveland Guardians pitching staff has a 3.70 ERA and a 1.27 WHIP. Steven Kwan leads the Cleveland Guardians with 169 hits and 56 RBI while Jose Ramirez and Kyle Manzardo have combined for 273 hits and 155 RBI.

Joey Cantillo gets the ball for the Cleveland Guardians, and he is 5-3 with a 3.21 ERA and 100 strikeouts this season. This will be Cantillo’s first career game against the Texas Rangers.

Texas Rangers @ Cleveland Guardians Betting Trends: September 27, 2025

• Probable Starting Pitcher: Joey Cantillo      Record this season: 5-3      ERA: 3.21
• Home Record: 2-2
• Last 5 against Rangers: –

Why the Cleveland Guardians will win

• The Rangers have lost each of their last nine road games against the Guardians following a road win.
• The Guardians have won nine of their last 10 home games against the Rangers following a home loss.
• The Rangers have failed to cover the run line in each of their last nine road games against the Guardians following a road win.
• The Guardians have covered the run line in nine of their last 10 home games against the Rangers following a home loss.
• The Rangers have lost the first inning in three of their last four road games.
• The Rangers have trailed after 5 innings in five of their last six road games.
• The Rangers have trailed after 3 innings in six of their last seven games against American League opponents.

• Probable Starting Pitcher: TBD

Why the Texas Rangers will win

• The underdogs have won eight of the Rangers’ last nine games.
• The Guardians have lost three of their last four games as favorites.
• The underdogs have covered the run line in eight of the Rangers’ last nine games.
• The Guardians have failed to cover the run line in five of their last six games as favorites following a loss.
• The Guardians have trailed after 5 innings in four of their last five home games against opponents that held a winning record.
• The Guardians have trailed after 3 innings in four of their last five games against opponents that held a winning record.

Total Runs Facts

• Eight of the Guardians’ last nine home games after playing the previous day have gone UNDER the total runs line.
• Each of the Rangers’ last four night games as underdogs have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rangers’ last seven games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 13 of the last 15 night games between the Rangers and Guardians.

Cleveland Guardians Player Prop Facts

• Steven Kwan has recorded at least one hit in each of his nine previous Saturday appearances against AL West teams that held a winning record.
• Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
• Lane Thomas has hit a home run in two of his last three appearances in night games against AL teams that held a winning record.

Texas Rangers Player Prop Facts

• Josh Jung has recorded at least one hit in each of the Rangers’ last eight games against AL opponents that held a winning record.
• Corey Seager has recorded a Double in three of his last four appearances with the Rangers as underdogs.
• Corey Seager has hit a home run in each of his last two appearances.

Guardians vs Rangers Prediction

The Rangers haven’t won two straight games in two weeks, and they have nothing to play for this weekend. Latz has been incredible this month, allowing 12 hits and 3 runs in 17 innings, but he usually doesn’t go deep into games. The Guardians have lost just 4 games since September 5, and they need to keep winning to lock up the AL Central. Cantillo has allowed just 25 hits and 5 runs in his last 34 innings. The Guardians have won 7 of Cantillo’s last 11 starts. Must win game for the Guardians, and they’ve been so hot this month, there’s no reason to believe they’ll fall short. Give me the Guardians.