Guardians vs Rays Prediction 8/25/25 MLB Picks Today
Tampa Bay Rays (63-67) vs. Cleveland Guardians (64-65)
August 25, 2025 6:40 pm EDT
The Line: Cleveland Guardians -151 / Tampa Bay Rays 124; Over/Under: 8.5
(Get latest betting odds)
In this article we will formulate a Guardians vs Rays prediction for this MLB game on Monday, August 25th at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup.
Cleveland Guardians Betting Preview
The Cleveland Guardians are 64-65 this year after they lost all three games against Texas by scores of 3-4, 0-10, and 0-5. In their game three loss, Cleveland fell behind in the fourth inning and never recovered in the shutout loss. The Guardians recorded five hits and they committed one error in the game, while they were led by Rocchio, who had two hits in the loss. Cleveland started Williams, who allowed three hits and three earned runs over 3.1 innings for the loss, while Sabrowski allowed one earned run in relief.
Prior to that series, the Guardians lost two out of three against the Diamondbacks and all three against the Braves. Cleveland has lost eight of their last nine games and they are third in the AL Central standings. The Cleveland pitching staff has a 3.93 ERA with a 1.32 WHIP and a .243 opponent batting average, while the offense has scored 501 runs with a .225 batting average and a .297 on base percentage this season. Jose Ramirez has led Cleveland with 26 home runs and 68 RBIs, while Kyle Manzardo has added 21 home runs and 55 RBIs this year. The projected starting pitcher for Cleveland is Tanner Bibee, who is 9-9 with a 4.62 ERA and a 1.29 WHIP over 142.1 innings pitched this year.
Tampa Bay Rays Betting Preview
The Tampa Bay Rays are 63-67 this season after they won two out of three against St. Louis by scores of 4-7, 10-6, and 7-2. In their game three win, Tampa Bay led 7-0 in the sixth inning and cruised to the easy win. The Rays recorded eight hits and they committed one error in the game, while they were led by Caminero, who went 1-4 with one home run and four RBIs in the win. Tampa Bay started Pepiot, who allowed one hit and zero earned runs over 5.0 innings for the win, while Van Belle allowed one earned run in relief.
Prior to that series, the Rays lost both games against the Yankees, but did win two out of three against the Giants before that. Tampa Bay has lost four of their last six games and they are currently fourth in the AL East standings. The Tampa Bay pitching staff has a 4.00 ERA with a 1.22 WHIP and a .239 opponent batting average, while the offense has scored 584 runs with a .251 batting average and a .315 on base percentage this season. Junior Caminero has led Tampa Bay with 37 home runs and 91 RBIs, while Brandon Lowe has added 25 home runs and 63 RBIs for the Rays this year. The projected starting pitcher for Tampa Bay is Ian Seymour, who is 1-0 with a 3.86 ERA and a 1.16 WHIP over 23.1 innings pitched this season.
Why the Guardians will beat the Rays
- The Rays have lost each of their last 10 games as underdogs against American League opponents following a win.
- The home team has won each of the Guardians’ last five games.
- The Rays have failed to cover the run line in seven of their last eight games as underdogs after playing the previous day.
- The Guardians have covered the run line in five of their last six games against the Rays following a road loss.
- The Rays have trailed after 3 innings in each of their last four games as underdogs against American League opponents.
- The Rays have trailed after 5 innings in each of their last four games as underdogs against American League opponents.
- The Rays have lost the first inning in three of their last four games as underdogs against American League opponents.
Why the Rays will beat the Guardians
- The Guardians have lost five of their last six games as favorites after playing the previous day.
- The underdogs have won four of the Guardians’ last five games at Progressive Field.
- The Rays have covered the run line each of their last six road games against AL Central opponents that held a losing record.
- The Guardians have failed to cover the run line in eight of their last nine home games against teams that held a losing record.
- The Rays have led after 5 innings in five of their last six road games against AL Central opponents that held a losing record.
Total Runs Facts
- Each of the last eight games between the Rays and Guardians have gone UNDER the total runs line.
- Each of the Rays’ last seven games as underdogs against the Guardians have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last six night games.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rays’ last four night games.
Cleveland Guardians Player Prop Facts
- Jose Ramirez has hit a home run in each of the Guardians’ last two home games against AL opponents.
- Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
- Jose Ramirez has recorded at least one hit in each of the Guardians’ last 13 home games against AL East opponents that held a losing record.
Tampa Bay Rays Player Prop Facts
- Brandon Lowe has hit a home run in three of the Rays’ last four night games against AL opponents that held a losing record.
- Josh Lowe has recorded a Double in each of his last three road appearances against AL opponents.
- Yandy Diaz has recorded at least one hit in each of his last nine appearances in night games against teams that held a losing record.
Matchup/League Facts
- The Guardians rank 30th in the league for hits this season (953).
- The Guardians rank 30th in the league for batting average this season (.225).
- The Rays rank 1st in the league for steals this season (171).
- The Rays are one of only four teams in the league to rank top 10 in both steals and batting average this season.
Guardians vs Rays Prediction
Both of these teams come into this matchup below .500 on the season, but Tampa Bay has won two games in a row and they have scored 17 runs in those two games. The Rays are 29-34 on the road this year, while the Guardians are 31-31 at home. Cleveland has been shutout in back to back games and they are starting Bibee, who has allowed four earned runs in four of his last five starts. Tampa Bay is going with Seymour, who has allowed eight earned runs and nine hits in his last 6.1 innings. Take the over in this matchup.