Guardians vs Rays Prediction 8/27/25 MLB Picks Today

In this article we will formulate a Guardians vs Rays prediction for this MLB game on Wednesday, August 27th at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 65-66 this season after they split the first two games in this series by scores of 0-9 and 3-0. In their game two win, Cleveland scored all three runs in the first inning, which was enough to get the low scoring win. The Guardians recorded three hits in the game and they were led by Manzardo, Naylor, and Rocchio, who all had one RBI in the win. Cleveland started Messick, who allowed four hits and zero earned runs over 7.0 innings for the win, while Smith picked up the save. 

Prior to this series, the Guardians lost all three against the Rangers and two out of three against the Diamondbacks. Cleveland has lost six of their last seven games and they are third in the AL Central standings. The Cleveland pitching staff has a 3.94 ERA with a 1.31 WHIP and a .244 opponent batting average, while the offense has scored 504 runs with a .223 batting average and a .295 on base percentage this season. Jose Ramirez has led Cleveland with 26 home runs and 68 RBIs, while Kyle Manzardo has added 21 home runs and 56 RBIs this year. The projected starting pitcher for Cleveland is Slade Cecconi, who is 5-6 with a 4.41 ERA and a 1.28 WHIP over 96.0 innings pitched this season. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 64-68 this year after they lost game two by a score of 3-0 on Tuesday night. Tampa Bay did record more hits in the game, but they couldn’t find any runs in the shutout loss. The Rays had five hits in the game and they were led by Diaz, who went 3-4 in the defeat. Tampa Bay started Baz, who allowed three hits and three earned runs over 6.0 innings for the loss, while Jax and Montgomery closed out the game. 

Prior to this series, the Rays won two out of three against the Cardinals, but did lose both against the Yankees before that. Tampa Bay has won three of their last four games and they are currently fourth in the AL East standings. The Tampa Bay pitching staff has a 3.97 ERA with a 1.21 WHIP and a .237 opponent batting average, while the offense has scored 593 runs with a .251 batting average and a .314 on base percentage this season. Junior Caminero has led Tampa Bay with 39 home runs and 94 RBIs, while Brandon Lowe has added 25 home runs and 63 RBIs for the Rays this year. The projected starting pitcher for Tampa Bay is Drew Rasmussen, who is 10-5 with a 2.62 ERA and a 0.99 WHIP over 123.2 innings pitched this year. 

Why the Rays will beat the Guardians

• The Guardians have lost eight of their last nine day games against teams that held a losing record.
• The Rays have won each of their last five Wednesday day games against AL Central opponents.
• The Guardians have failed to cover the run line each of their last seven day games against American League opponents that held a losing record.
• The Rays have covered the run line in seven of their last eight road games against AL Central opponents that held a losing record.
• The Guardians have trailed after 5 innings in seven of their last eight games as underdogs against AL East opponents.
• The Guardians have trailed after 3 innings in four of their last five day games against AL East opponents.

Total Runs Facts

• Nine of the last 10 games between the Rays and Guardians have gone UNDER the total runs line.
• Five of the Rays’ last six games as favorites against American League opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the last nine day games between the Rays and Guardians.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Rays’ last four day games at Progressive Field.

Cleveland Guardians Player Prop Facts

• Carlos Santana has hit a home run in each of his last two appearances with his team as a home underdog against the Rays.
• Steven Kwan has recorded at least one hit in each of his 10 previous appearances in day games against AL East teams that held a losing record.

Tampa Bay Rays Player Prop Facts

• Brandon Lowe has hit a home run in each of the Rays’ last two games as road favorites against AL opponents.
• Drew Rasmussen has recorded five or more strikeouts in seven of his last eight appearances with the Rays as favorites against AL opponents.
• Brandon Lowe has recorded at least one hit in each of his last 11 appearances with the Rays as road favorites.
• Yandy Diaz has recorded a Double in four of the Rays’ last five road games against AL opponents.
• Drew Rasmussen has recorded a win in each of his last three appearances with the Rays as road favorites.

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Guardians vs Rays Prediction 

Cleveland finally snapped their losing streak with a win on Tuesday, but they have only scored in one of their last 36 innings. The Guardians are 32-32 at home this year, while the Rays are 30-35 on the road. Tampa Bay had their small losing streak ended last night, but they are going with Rasmussen, who has allowed a total of five earned runs in his last five starts. Cleveland is starting Cecconi, who has allowed 2, 6, and 5 earned runs in his last three outings. Neither team has much to play for, but I am going to back Rasmussen and the Rays here.