Guardians vs Red Sox Prediction 4/27/25 MLB Picks Today

The Boston Red Sox and Cleveland Guardians meet Sunday in MLB action at Progressive Field. Here’s a Guardians vs Red Sox Prediction. This article will include a Guardians vs Red Sox Pick.

Boston Red Sox Betting Preview

The Boston Red Sox are 15-14 on the year and play the Blue Jays, Twins, and Rangers next. The Boston Red Sox are batting .244 on the season, have a .327 OBP, and a .400 slugging percentage. The Boston Red Sox pitching staff has a 4.08 ERA and a 1.32 WHIP. Alex Bregman leads the Boston Red Sox with 36 hits and 22 RBI, while Jarren Duran and Trevor Story have combined for 62 hits and 29 RBI.

Brayan Bello gets the ball for the Boston Red Sox, and he is 1-0 with a 1.80 ERA and 3 strikeouts this season. This will be Bello’s second career game against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 15-11 on the year and play the Twins, Blue Jays, and Nationals next. The Cleveland Guardians are batting .237 on the season, have a .307 OBP, and a .386 slugging percentage. The Cleveland Guardians’ pitching staff has a 4.07 ERA and a 1.39 WHIP. Steven Kwan leads the Cleveland Guardians with 36 hits and 15 RBI, while Jose Ramirez and Gabriel Arias have combined for 46 hits and 25 RBI.

Logan Allen gets the ball for the Cleveland Guardians, and he is 1-1 with a 2.11 ERA and 16 strikeouts this season. This will be Allen’s second career game against the Boston Red Sox.

Why the Cleveland Guardians will win

• The Guardians have won each of their last eight games as home favorites.
• The Red Sox have lost each of their last five games against the Guardians following a win.
• The Red Sox have failed to cover the run line in each of their last five day games against AL Central opponents following a win.
• The Guardians have covered the run line in each of their last four day games at Progressive Field following a home loss.
• The Guardians have led after 5 innings in five of their last six games as favorites.
• The Red Sox have lost the first inning in each of their last three day games against American League opponents.

Why the Boston Red Sox will win

• The Red Sox have won three of their last four games as underdogs.
• The Guardians have lost three of their last four day games against AL East opponents that held a winning record.
• The Guardians have failed to cover the run line in five of their last six games against American League opponents after playing the previous day.
• The Red Sox have covered the run line in four of their last five games as underdogs against AL Central opponents following a win.
• The Red Sox have led after 5 innings in five of their last six games against AL Central opponents.
• The Guardians have lost the first inning in three of their last four games against AL East opponents.
• The Guardians have trailed after 3 innings in eight of their last nine Sunday games against American League opponents that held a winning record.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit at least one home run in three of the Guardians’ last four games as home favorites against the Red Sox.
• Jose Ramirez has recorded at least one RBI in five of the Guardians’ last six games as favorites against the Red Sox.
• Steven Kwan has recorded at least one Single in each of the Guardians’ last 10 games against AL opponents that held a winning record.
• Steven Kwan has recorded at least one hit in each of the Guardians’ last 10 games against AL opponents that held a winning record.
• Lane Thomas has scored a run in each of his last four appearances against the Red Sox.
• Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
• Steven Kwan ranks T2nd in the league in Hits (36) this season.

Boston Red Sox Player Prop Facts

• Rafael Devers has hit a home run in four of his last five appearances in day games against AL Central teams that held a winning record.
• Wilyer Abreu has recorded an RBI in each of the Red Sox’s last four games as underdogs against the Guardians.
• Alex Bregman has scored a run in each of the Red Sox’s last six day games.
• Alex Bregman has recorded a Single in each of his last seven road appearances against AL opponents that held a winning record.
• Alex Bregman has recorded at least one hit in each of his last 13 appearances in day games against AL Central teams that held a winning record.
• Alex Bregman ranks T2nd in the league in Hits (36) this season.

Guardians vs Red Sox Prediction

You can make a case for either the Red Sox or Guardians, as both teams have been solid over the last couple of weeks. The difference in this game is that Bello has just five innings this season and is still getting his feet wet. Allen has pitched in 21.1 innings this season, and he’s been strong, allowing 18 hits and five earned runs in those frames. Allen has allowed one earned run in his last three starts combined. In what should be a fun season finale between two teams playing good baseball, I’m going to lean toward the Guardians at home with the more trustworthy pitcher, given the larger sample size this season.