Guardians vs Red Sox Prediction 5/31/26 MLB Picks Today
Boston Red Sox (24-33) vs. Cleveland Guardians (34-26)
May 31, 2026 1:40 pm EDT
The Line: Cleveland Guardians -105 / Boston Red Sox -114; Over/Under: 7.5
(Get latest betting odds)
In this article we will formulate a Guardians vs Red Sox prediction for this MLB game on Sunday, May 31st at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup.
Cleveland Guardians Betting Preview
The Cleveland Guardians are 34-26 this season after they split the first two games in this series by scores of 4-3 and 1-9. In game two, Cleveland led 1-0 in the first inning, but they failed to score over the last eight innings for the loss. The Guardians recorded six hits and they committed four errors in the game, while they were led by Ramirez, who went 1-3 with one RBI. Messick allowed five hits and one earned run over 5.0 innings, while Festa picked up the loss in relief. Prior to this series, Cleveland lost two out of three against the Nationals, but did win two out of three against the Phillies before that.
This season, Cleveland has a 3.65 ERA with a 1.27 WHIP and a .237 opponent batting average, while they have scored 245 runs with a .231 batting average and a .319 on base percentage. Chase DeLauter has led the Guardians with seven home runs and 31 RBIs, while Jose Ramirez has added eight home runs and 28 RBIs. The projected starting pitcher for Cleveland is Tanner Bibee, who is 0-7 with a 4.57 ERA and a 1.32 WHIP over 63.0 innings pitched this season.
Boston Red Sox Betting Preview
The Boston Red Sox are 24-33 this year after they won game two by a score of 9-1 on Saturday. Boston tied the game at one in the fourth inning and they ran away with the blowout win in the later innings. The Red Sox recorded 11 hits in the game and they were led by Duran, who went 2-6 with one home run and three RBIs. Gray allowed four hits and one earned run over 6.0 innings for the win, while Slaten picked up a hold. Prior to this series, Boston lost two out of three against the Braves and all three against the Twins.
This season, Boston has a 3.82 ERA with a 1.26 WHIP and a .239 opponent batting average, while they have scored 222 runs with a .246 batting average and a .318 on base percentage. Willson Contreras has led the Red Sox with 11 home runs and 33 RBIs, while Jarren Duran has added nine home runs and 32 RBIs. The projected starting pitcher for Boston is Ranger Suarez, who is 2-3 with a 3.02 ERA and a 1.08 WHIP over 53.2 innings pitched this year.
Why the Cleveland Guardians will win
- The Guardians have won each of their last four games as underdogs against American League opponents.
- The Red Sox have lost six of their last seven games as favorites following a win.
- The Guardians have covered the run line in each of their last eight games as home underdogs.
- The Red Sox have failed to cover the run line in eight of their last nine games as favorites following a win.
- The Red Sox have lost the first inning in eight of their last nine road games against opponents that held a winning record.
- The Guardians have led after 5 innings in each of their last four games as underdogs against American League opponents.
- The Guardians have led after 3 innings in each of their last five home games against opponents that held a losing record.
Why the Boston Red Sox will win
- The Red Sox have won eight of their last nine road games against AL Central opponents.
- The Guardians have lost three of their last four games after playing the previous day.
- The Red Sox have covered the run line in each of their last seven road games against American League opponents.
- The Guardians have failed to cover the run line in each of their last five games.
- The Guardians have trailed after 3 innings in each of their last four games as home underdogs against AL East opponents.
- The Guardians have trailed after 5 innings in each of their last four games as home underdogs against AL East opponents.
Total Runs Facts
- Each of the Guardians’ last six games as underdogs against the Red Sox have gone OVER the total runs line.
- Seven of the Red Sox’s last eight games as favorites against the Guardians have gone OVER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last seven games against American League opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the last five games between the Red Sox and Guardians.
Cleveland Guardians Player Prop Facts
- Rhys Hoskins has hit a home run in two of his last three appearances with his team as a home underdog against the Red Sox.
- Rhys Hoskins has recorded at least one hit in each of his 12 previous appearances with his team as an underdog against the Red Sox.
Boston Red Sox Player Prop Facts
- Jarren Duran has hit a home run in three of the Red Sox’s last four road games.
- Ranger Suarez has recorded five or more strikeouts in each of his last four road appearances against AL opponents that held a winning record.
- Isiah Kiner-Falefa has recorded at least one hit in each of his last 12 appearances against the Guardians.
- Ranger Suarez has recorded a win in three of his last four road appearances against AL opponents that held a winning record.
Guardians vs Red Sox Prediction
Cleveland fell apart defensively in game two on Saturday, but they have won two of their last three games and will look for the series win here. The Guardians are 17-13 at home this year, while the Red Sox are 15-14 on the road. Boston has split their last four games and they have scored 6+ runs in three of their last five. The Red Sox are starting Suarez, who has allowed one earned run or fewer in four of his last five outings, while Bibee has allowed 7, 1, 3, 1, and 4 earned runs in his last five starts. Take the Red Sox to get another win here.