Guardians vs Reds Prediction 5/17/26 MLB Picks Today

In this article we will formulate a Guardians vs Reds prediction for this MLB game on Sunday, May 17th at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 25-22 this year after they split the first two games in this series by scores of 6-7 and 7-4. In game two, Cleveland trailed 4-2 in the fifth inning, but they scored the last five runs to get the win. The Guardians recorded 10 hits in the game and they were led by Martinez, who went 2-4 with one home run and two RBIs. Cantillo allowed four hits and four earned runs over 5.0 innings, while Sabrowski picked up the win and Smith got the save. Prior to this series, Cleveland won all three against the Angels, but lost two out of three against the Twins before that. 

This season, Cleveland has a 3.88 ERA with a 1.27 WHIP and a .237 opponent batting average, while they have scored 200 runs with a .230 batting average and a .325 on base percentage. Chase DeLauter has led the Guardians with six home runs and 26 RBIs, while Jose Ramirez has added six home runs and 17 RBIs. The projected starting pitcher for Cleveland is Gavin Williams, who is 5-3 with a 3.74 ERA and a 1.17 WHIP over 55.1 innings pitched this year. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 24-22 this season after they lost game two by a score of 7-4 on Saturday night. Cincinnati took a 4-2 lead in the fifth inning, but they failed to score any more runs for the loss. The Reds recorded five hits and they committed one error in the game, while they were led by Steer, who went 1-4 with two RBIs. Paddack allowed six hits and two earned runs over 5.0 innings, while Moll picked up the loss in relief. Prior to this series, Cincinnati lost two out of three against the Nationals, but did win two out of three against the Astros before that. 

This season, Cincinnati has a 4.68 ERA with a 1.48 WHIP and a .251 opponent batting average, while they have scored 201 runs with a .225 batting average and a .311 on base percentage. Sal Stewart has led the Reds with 10 home runs and 31 RBIs, while Elly De La Cruz has added 10 home runs and 30 RBIs. The projected starting pitcher for Cincinnati is Brady Singer, who is 2-3 with a 5.79 ERA and a 1.67 WHIP over 42.0 innings pitched this season. 

Why the Cleveland Guardians will win

• The Reds have lost each of their last nine road games following a road loss.
• The Guardians have won seven of their last eight day games against the Reds following a win.
• The Guardians have covered the run line in four of their last five home games against National League opponents.
• The Reds have failed to cover the run line in five of their last six games as underdogs against the Guardians following a loss.
• The Reds have lost the first inning in each of their last three day games against AL Central opponents.
• The Reds have trailed after 3 innings in each of their last five day games against AL Central opponents.
• The Reds have trailed after 5 innings in six of their last seven road day games.

Why the Cincinnati Reds will win

• The Guardians have lost each of their last four games as favorites against National League opponents following a win.
• The Reds have won each of their last four games as underdogs against American League opponents following a loss.
• The Guardians have failed to cover the run line each of their last seven Sunday games against teams that held a winning record.
• The Reds have covered the run line in each of their last four games as underdogs against American League opponents following a loss.
• The Guardians have trailed after 3 innings in four of their last five home games against National League opponents that held a winning record.
• The Reds have led after 5 innings in each of their last four games against American League opponents.

Total Runs Facts

• Each of the Reds’ last eight day games against AL Central opponents have gone OVER the total runs line.
• Each of the Guardians’ last six games as favorites against NL Central opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last eight home games against National League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Reds’ last nine games.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in seven of the Guardians’ last 15 games as favorites against NL Central opponents.
• Jose Ramirez has recorded at least one hit in each of the Guardians’ last 11 games against the Reds.

Cincinnati Reds Player Prop Facts

• Elly De La Cruz has hit a home run in three of the Reds’ last five day games against AL Central opponents that held a winning record.
• Brady Singer has recorded five or more strikeouts in nine of his last 10 appearances in day games.
• Elly De La Cruz has recorded at least one hit in each of the Reds’ last 15 road games against AL Central opponents.
• Brady Singer has recorded a win in four of his last five appearances against AL Central opponents.

Guardians vs Reds Prediction 

Cleveland bounced back from their loss on Friday with a win on Saturday and they have won four of their last five games. The Guardians are 14-10 at home this year, while the Reds are 11-11 on the road. Cincinnati has won two of their last three games, but they have allowed 6+ runs in four of their last five. The Reds are starting Singer, who has allowed 3, 4, and 4 earned runs in his last three starts, while Williams has allowed 5+ earned runs in three of his last four starts. Take the over here.