Guardians vs Reds Prediction 6/10/25 MLB Picks Today

The Cincinnati Reds and Cleveland Guardians meet Tuesday in MLB action at Progressive Field. Here’s a Guardians vs Reds Prediction. This article will include a Guardians vs Reds Pick.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 34-33 on the year and play the Tigers, Twins, and Cardinals next. The Cincinnati Reds are batting .247 on the season, have a .322 OBP, and a .401 slugging percentage. The Cincinnati Reds pitching staff has a 3.71 ERA and a 1.19 WHIP. TJ Friedl leads the Cincinnati Reds with 71 hits and 24 RBI, while Elly De La Cruz and Gavin Lux have combined for 120 hits and 70 RBI.

Andrew Abbott gets the ball for the Cincinnati Reds, and he is 5-1 with a 2.18 ERA and 59 strikeouts this season. Abbott is 2-1 with a 3.65 ERA and 11 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 34-31 on the year and play the Mariners, Giants, and Athletics next. The Cleveland Guardians are batting .234 on the season, have a .307 OBP, and a .376 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.98 ERA and a 1.38 WHIP. Jose Ramirez leads the Cleveland Guardians with 79 hits and 32 RBI, while Steven Kwan and Carlos Santana have combined for 130 hits and 52 RBI.

Slade Cecconi gets the ball for the Cleveland Guardians, and he is 1-2 with a 4.87 ERA and 20 strikeouts this season. Cecconi is 0-2 with a 4.57 ERA and 18 strikeouts in his career against the Cincinnati Reds.

Why the Cleveland Guardians will win

• The Reds have lost seven of their last eight night games against the Guardians at Progressive Field following a road win.
• The Guardians have won seven of their last eight home games against NL Central opponents following a loss.
• The favorites have covered the run line in five of the Guardians’ last six games at Progressive Field.
• The Reds have failed to cover the run line in four of their last five games against American League opponents following a road win.
• The Reds have lost the first inning in three of their last four games at Progressive Field against American League opponents that held a winning record.
• The Reds have trailed after 3 innings in each of their last six games at Progressive Field.
• The Guardians have led after 5 innings in four of their last five night games at Progressive Field against NL Central opponents.

Why the Cincinnati Reds will win

• The Reds have won each of their last five games as underdogs against American League opponents.
• The Guardians have lost each of their last four games as favorites against National League opponents.
• The Reds have covered the run line in seven of their last eight games against American League opponents.
• The Guardians have failed to cover the run line in seven of their last eight games against National League opponents.
• The Guardians have trailed after 3 innings in each of their last three night games against National League opponents that held a winning record.
• The Guardians have trailed after 5 innings in eight of their last nine games against National League opponents that held a winning record.

Cleveland Guardians Player Prop Facts

• Carlos Santana has hit a home run in three of his last four appearances in night games against NL Central teams that held a winning record.
• Carlos Santana has recorded at least one RBI in nine of his last 10 appearances against the Reds at Progressive Field.
• Jose Ramirez has scored at least one run in each of the Guardians’ last seven home games against NL Central opponents.
• Lane Thomas has recorded at least one hit in each of his last six appearances in night games against NL Central teams that held a winning record.
• Jose Ramirez has recorded a Single in each of the Guardians’ last six home games.
• Jose Ramirez ranks T3rd in the league in Hits (79) this season.

Cincinnati Reds Player Prop Facts

• Will Benson has hit at least one home run in three of the Reds’ last four games against the Guardians.
• TJ Friedl has recorded at least one hit in each of his last 16 road appearances against AL Central opponents.
• Jose Trevino has recorded a Double in six of his last seven appearances with the Reds as underdogs against AL opponents.
• TJ Friedl has recorded at least one Single in each of the Reds’ last 10 road games against AL opponents that held a winning record.
• Jeimer Candelario has recorded at least one RBI in each of his last four appearances against the Guardians.
• Jeimer Candelario has scored at least one run in each of his last nine road appearances against AL Central opponents.
• Elly De La Cruz ranks T6th in the league in Steals (19) this season.

Guardians vs Reds Prediction

The Reds are finally starting to look like the team we expected to see from the start and stringing wins together. Abbott has been an all-star caliber pitcher this season with a 2.18 ERA and 1.06 WHIP, and he had a May where he allowed two earned runs in 32.2 innings. The Guardians are seeing some frustrating results lately, and Cecconi hasn’t been great, allowing 22 hits and 11 runs in 20.1 innings. In 4.1 home innings, Cecconi has a 10.38 ERA and .368 allowed batting average. The Reds are playing the better baseball and have the edge on the mound. This price is a steal. Give me the road team.