Guardians vs Tigers Prediction 5/25/25 MLB Picks Today

The Cleveland Guardians are visiting Detroit Tigers on Sunday, May 25^th at the Comerica Park in the fourth and final game of this series, with the Guardians having a 3-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cleveland Guardians vs Detroit Tigers Prediction. We will examine:

The Detroit Tigers recent form and player performance

The Cleveland Guardians recent form and player performance

Recent betting trends and streaks involving the Detroit Tigers

Recent betting trends and streaks involving the Cleveland Guardians

Recent betting trends in games played between the Cleveland Guardians vs Detroit Tigers

A summary that ties it all together and produces a favorable betting outcome for A Cleveland Guardians vs Detroit Tigers game

Detroit Tigers Preview

The Detroit Tigers have a 33-20 record this season and are sitting on the first place of the AL Central. The Tigers have a 17-8 home record and are 26-22 in over/under. They are coming off a 5-7 home defeat by the Guardians, and have three consecutive losses. Under is 3-1 in their last 4 games and are playing the Royals and the Giants next.

The Tigers have a .253 batting average this season, .326 OBP and .412 slugging percentage. Detroit’s pitching staff has a 3.38 ERA and 1.18 WHIP. Riley Greene leads the Tigers with 54 hits, while Spencer Torkelson leads the team in RBI, with 40, and in home runs with 13. Kerry Carpenter is the team’s best hitter with a .281 batting average.

Tarik Skubal (R) will take the mound for the Tigers, and he has a 4-2 record, 2.87 ERA and 0.94 WHIP. He has been better at home with a 2.37 ERA across five home starts, but he has struggled in his last two starts, with 8 earned runs in 11.3 innings pitched. Tarik Skubal is 2-2 with an ERA of 3.46 and 44 strikeouts in 8 appearances versus the Guardians in his career.

Cleveland Guardians Preview

The Cleveland Guardians have a 29-22 record this season and are sitting on the second place of the AL Central. The Guardians have a 15-14 road record and are 24-24 in over/under They are coming off a 7-5 road victory over the Tigers, and have four consecutive wins. Under is 3-1 in their last 4 games, and are playing the Dodgers and the Angels next.

The Guardians have a .234 batting average this season, .307 OBP and .382 Slugging percentage. Cleveland’s pitching staff has a 3.96 ERA and 1.38 WHIP. Steven Kwan leads the Guardians with 65 hits and a team-high .320 batting average. Carlos Santana adds a team-high 27 RBI and Kyle Manzardo adds a team-high 10 home runs.

Logan Allen (R) will take the mound for the Guardians, and he has a 2-2 record, 3.86 ERA and 1.53 WHIP. He has been better on the road with a 3.68 ERA across six road starts, and he has given up 2+ runs in four of his last five starts. This will be his first career start against the Tigers.

Why the Detroit Tigers will win

• The Guardians have lost eight of their last nine road games following an extra innings win.
• The Tigers have won eight of their last nine games after going to extra innings.
• The Tigers have covered the run line each of their last seven day games against teams that held a winning record.
• The Guardians have failed to cover the run line in four of their last five day games against the Tigers at Comerica Park following a win.
• The Guardians have lost the first inning in three of their last four day games at Comerica Park.
• The Guardians have trailed after 5 innings in each of their last five road day games.
• The Tigers have led after 3 innings in 10 of their last 11 day games.

Why the Cleveland Guardians will win

• The Guardians have won each of their last seven games as underdogs following a road win.
• The Tigers have lost seven of their last eight games as favorites against American League opponents following a home loss.
• The Tigers have failed to cover the run line in each of their last 10 games as favorites.
• The Guardians have covered the run line in each of their last eight games as road underdogs against AL Central opponents.
• The Guardians have led after 5 innings in three of their last four games against the Tigers.

Total Runs Facts

• Each of the Tigers’ last four games after going to extra innings have gone OVER the total runs line.
• Four of the Guardians’ last five day games after playing the previous day have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Tigers’ last nine day games at Comerica Park.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last six Sunday games.

Matchup/League Facts

• The Tigers rank 30th in the league for steals this season (20).
• The Tigers rank 4th in the league for runs scored this season (273).
• The Guardians rank 25th in the league for hits this season (390).
• The Guardians rank T24th in the league for walks allowed this season (186).

Guardians vs Tigers Prediction

The Guardians are 8-2 in their last 10 overall meetings against the Tigers, and 6-1 in their last 7 visits in Detroit. Under is 4-2 in their last 6 meetings in Detroit.

In this Guardians vs Tigers Prediction, the Tigers are coming as huge -245 home favorites. The Tigers are rightfully favored, as they have a better overall record this season, and have been extremely strong at home, while the Guardians are mediocre on the road, but the Guardians have been dominating the Tigers in this series.

The Tigers are putting their ace on the mound in Tarik Skubal, while the Guardians answer with the shaky Logan Allen. Tigers have the better bullpen and better batting average and I don’t think they will be swept in a four-game home series. The price is huge for a reason. Take the Detroit Tigers on the runline.