Guardians vs Tigers Prediction 10/1/25 MLB Picks Today

The Detroit Tigers and Cleveland Guardians meet Wednesday in Wild Card Game 2 MLB action at Progressive Field. Here’s a Guardians vs Tigers Prediction. This article will include a Guardians vs Tigers Pick.

Detroit Tigers Betting Preview

The Detroit Tigers look to make the ALDS for a second straight season. The Detroit Tigers are batting .167 on the season, have a .242 OBP, and a .200 slugging percentage. The Detroit Tigers pitching staff has a 1.00 ERA and a 0.78 WHIP. Javier Baez leads the Detroit Tigers with 2 hits, while Kerry Carpenter and Riley Greene have combined for 2 hits.

Casey Mize gets the ball for the Detroit Tigers, and he is 14-6 with a 3.87 ERA and 139 strikeouts this season. This will be Mize’s career postseason debut. Mize is 1-1 with a 3.00 ERA and 19 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians need a win to force a game 2 on Thursday. The Cleveland Guardians are batting .133 on the season, have a .212 OBP, and a .133 slugging percentage. The Cleveland Guardians pitching staff has a 0.00 ERA and a 0.78 WHIP. Angel Martinez leads the Cleveland Guardians with 1 hit while Jose Ramirez and Kyle Manzardo have combined for 2 hits.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 12-11 with a 4.24 ERA and 162 strikeouts this season. Bibee is 0-1 with a 3.45 ERA and 16 strikeouts in his postseason career. Bibee is 4-3 with a 3.62 ERA and 48 strikeouts in his career against the Detroit Tigers.

Detroit Tigers @ Cleveland Guardians Betting Trends: October 1, 2025

• Probable Starting Pitcher: Tanner Bibee       Record this season: 12-11      ERA: 4.24
• Home Record: 5-5
• Last 5 against Tigers: 3-0

Why the Cleveland Guardians will win

• The Tigers have lost nine of their last 10 games following a win.
• The Guardians have won each of their last six games as home favorites against the Tigers following a home loss.
• The Tigers have failed to cover the run line in seven of their last eight games against AL Central opponents.
• The Guardians have covered the run line each of their last seven Wednesday games against teams that held a winning record.
• The Guardians have won the first inning in three of their last four day games.
• The Tigers have trailed after 3 innings in four of their last five day games.
• The Guardians have led after 5 innings in each of their last seven Wednesday games against American League opponents that held a winning record.

• Probable Starting Pitcher: Casey Mize      Record this season: 14-6      ERA: 3.87
• Road Record: 6-4
• Last 5 against Guardians: 1-1

Why the Detroit Tigers will win

• The Tigers have won five of their last six games as underdogs against AL Central opponents.
• The Guardians have lost each of their last five day games following a loss.
• The Tigers have covered the run line in each of their last 10 Wednesday day games as underdogs against American League opponents.
• The Guardians have failed to cover the run line in each of their last five playoff games after playing the previous day.
• The Guardians have trailed after 3 innings in four of their last five games.
• The Tigers have led after 5 innings in each of their last six Wednesday day games against opponents that held a winning record.

Total Runs Facts

• Each of the Tigers’ last six games have gone UNDER the total runs line.
• Nine of the Guardians’ last 10 home games against AL Central opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Guardians’ last five games.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 13 of the Tigers’ last 16 day games against AL Central opponents.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has recorded at least one Double in each of the Guardians’ last four games as home favorites against the Tigers.
• Jose Ramirez has recorded at least one hit in each of the Guardians’ last nine games against AL Central opponents.
• Lane Thomas has hit a home run in two of his three previous home playoff appearances against the Tigers.
• Jose Ramirez ranks T2nd in the league in Steals (44) this season.

Detroit Tigers Player Prop Facts

• Riley Greene has hit a home run in three of the Tigers’ last five road games against the Guardians.
• Javier Baez has recorded at least one hit in each of his last 15 appearances with the Tigers as underdogs against AL opponents.
• Jake Rogers has recorded a Double in three of his last four appearances against AL Central opponents.
• Casey Mize ranks T8th in the league for Wins (14) this season.

Matchup/League Facts

• The Guardians rank 30th in the league for hits this season (1199).
• The Guardians rank 29th in the league for batting average this season (.226).
• The Tigers rank 30th in the league for steals this season (61).
• The Tigers rank 3rd in the league for triples this season (36).

Guardians vs Tigers Prediction

The Guardians let me down yesterday because they couldn’t bring home a run with a guy on third with nobody out. I’m going back to the well in game 2. The Guardians have lost back-to-back games just once since September 3. Mize is making his playoff debut, so there’s no telling how he’s going to handle the pressure, and he’s allowing a .274 batting average in 75.2 road innings. Bibee has allowed 16 hits and 4 runs in his last 27.2 innings, and he has a 3.22 ERA and .226 allowed batting average in 86.2 home innings. I expect the Guardians to bounce back and force a deciding game 3 on Thursday.