Detroit Tigers (85-73) vs. Cleveland Guardians (86-72)
September 25, 2025 6:40 pm EDT
The Line: Cleveland Guardians 0.0001 / Detroit Tigers 0.0001; Over/Under: 0.0001
(Get latest betting odds)
The Detroit Tigers and Cleveland Guardians meet Thursday in MLB action at Progressive Field. Here’s a Guardians vs Tigers Prediction. This article will include a Guardians vs Tigers Pick.
Detroit Tigers Betting Preview
The Detroit Tigers are 85-73 on the year and play the Red Sox next. The Detroit Tigers are batting .247 on the season, have a .316 OBP, and a .415 slugging percentage. The Detroit Tigers pitching staff has a 3.97 ERA and a 1.25 WHIP. Riley Greene leads the Detroit Tigers with 154 hits and 110 RBI, while Gleyber Torres and Spencer Torkelson have combined for 267 hits and 152 RBI.
The Detroit Tigers didn’t announce a starting pitcher at the time this article was published.
Cleveland Guardians Betting Preview
The Cleveland Guardians are 86-72 on the year and play the Rangers next. The Cleveland Guardians are batting .226 on the season, have a .297 OBP, and a .373 slugging percentage. The Cleveland Guardians pitching staff has a 3.68 ERA and a 1.26 WHIP. Steven Kwan leads the Cleveland Guardians with 169 hits and 56 RBI while Jose Ramirez and Kyle Manzardo have combined for 271 hits and 152 RBI.
Parker Messick gets the ball for the Cleveland Guardians, and he is 3-0 with a 2.08 ERA and 31 strikeouts this season. This will be Messick’s first career game against the Detroit Tigers.
Detroit Tigers @ Cleveland Guardians Betting Trends: September 25, 2025
- Probable Starting Pitcher: Parker Messick Record this season: 3-0 ERA: 2.08
- Home Record: 2-0
- Last 5 against Tigers: –
Why the Cleveland Guardians will win
- The Guardians have won each of their last nine night games against AL Central opponents.
- The Tigers have lost each of their last eight games.
- The Guardians have covered the run line in each of their last 12 night games against AL Central opponents following a win.
- The Tigers have failed to cover the run line in each of their last eight games.
- The Guardians have led after 5 innings in 14 of their last 16 night games against AL Central opponents.
- The Tigers have trailed after 3 innings in four of their last five games.
- Probable Starting Pitcher: TBD
Why the Detroit Tigers will win
- The Tigers have won 12 of their last 13 games against AL Central opponents following a road loss.
- The Guardians have failed to cover the run line in nine of their last 10 home games against the Tigers following a home win.
- The Tigers have covered the run line in 10 of their last 12 games against the Guardians following a road loss.
- The Tigers have led after 5 innings in three of their last four road games.
Total Runs Facts
- Each of the Guardians’ last seven home games after playing the previous day have gone UNDER the total runs line.
- Four of the Tigers’ last five road games against AL Central opponents have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last seven games between the Tigers and Guardians.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Tigers’ last five games against AL Central opponents.
Cleveland Guardians Player Prop Facts
- Jose Ramirez has recorded at least one hit in each of the Guardians’ last seven games.
- Lane Thomas has hit a home run in two of his last three appearances in night games against AL teams that held a winning record.
Detroit Tigers Player Prop Facts
- Jake Rogers has recorded a Double in three of his last four appearances against AL Central opponents.
- Riley Greene has hit a home run in two of the Tigers’ last three road games against the Guardians.
- Riley Greene has recorded at least one hit in each of the Tigers’ last six road games against AL Central opponents that held a winning record.
Matchup/League Facts
- The Guardians rank 30th in the league for hits this season (1172).
- The Guardians rank 29th in the league for batting average this season (.226).
- The Tigers rank 30th in the league for steals this season (60).
- The Tigers rank T2nd in the league for triples this season (36).
Guardians vs Tigers Prediction
The Tigers look like a team that doesn’t want to participate in the postseason, as they’ve won just one game since September 11. The Tigers have scored 2 or fewer runs in 6 of their last 7 games. Meanwhile, the Guardians have lost just twice since September 5. With only a few games left to play, these are two teams heading in opposite directions. It’s hard to do anything but side with the Guardians with what we’ve seen over the last two weeks.
