Houston Astros vs Boston Red Sox Prediction 3/31/26 MLB Picks Today

The Boston Red Sox and the Houston Astros meet Tuesday in MLB action from Daikin Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Houston Astros prediction.

Starting Pitching Matchup

The Boston Red Sox will send out Brayan Bello for the start here and Bello was 11-9 with a 3.35 ERA and 124 strikeouts last season. In his career, Bello is 1-1 with a 2.31 ERA and 6 strikeouts against the Astros. Hunter Brown will start for Houston here and is 0-0 with a 0.00 ERA and 9 strikeouts this season. In his career, Brown is 2-0 with a 1.89 ERA and 19 strikeouts against Boston.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to bounce back from an 8-1 loss at the hands of the Astros in Monday’s series opener to sit at 1-3 this season. After this series, the Red Sox will head home for a game against the San Diego Padres.

Red Sox Lose 3 In A Row

Going into Monday’s opener with Houston, Wilyer Abreu leads the Red Sox with 6 hits including 2 doubles, 2 home runs and 4 RBIs while Trevor Story has a homer and 2 RBIs and Marcelo Mayer’s added 3 hits with a pair of doubles as well. Roman Anthony has 4 hits so far this season while Carlos Narvaez has added 3 hits and Connor Wong and Andruw Monasterio each have a double. 

Why the Boston Red Sox will win

• The Astros have lost each of their last five games as favorites against AL East opponents following a home win.
• The underdogs have won each of the Red Sox’s last three games.
• The Astros have failed to cover the run line in 12 of their last 13 home games against AL East opponents that held a losing record.
• The Red Sox have covered the run line in each of their last six Tuesday road games.

Boston Red Sox Player Prop Facts

• Trevor Story has recorded at least one hit in each of the Red Sox’s last nine road games against AL opponents.
• Triston Casas has hit a home run in each of his last three appearances in night games against AL West teams that held a winning record.
• Wilyer Abreu ranks T2nd in the league in Hits (8) this season.

Houston Astros Recap

The Houston Astros come into this game looking to add on to their win over Boston from Monday’s opening game to improve to 3-2 this season. After this series, the Astros will head on the road for a series against the Athletics.

Astros Pick Up Third Straight Win

Isaac Paredes has 3 doubles and 4 RBIs to lead the Astros while Yordan Alvarez has 4 hits with a home run, a double and two RBIs. Christian Walker has 4 hits with 3 doubles and 3 RBIs and Yainer Diaz, Jake Meyers, Carlos Correa and Christian Vazquez all have 2 RBIs as well this season. 

Why the Houston Astros will win

• The Red Sox have lost each of their last five road games after playing the previous day.
• The Astros have won each of their last five night games against AL East opponents that held a losing record.
• The Red Sox have failed to cover the run line in seven of their last eight games after playing the previous day.
• The Astros have covered the run line each of their last five games against AL East opponents that held a losing record.

Houston Astros Player Prop Facts

• Christian Walker has hit at least one home run in three of his last four appearances against opponents that held a losing record.
• Christian Walker has recorded at least one hit in each of his last nine appearances against opponents that held a losing record.
• Jose Altuve ranks T4th amongst qualified players for On Base Percentage (.565) this season.

Total Runs Facts

• Ten of the Red Sox’s last 11 games as underdogs against AL West opponents have gone UNDER the total runs line.
• Each of the Astros’ last four games as favorites against the Red Sox have gone UNDER the total runs line.

Boston Red Sox vs. Houston Astros Prediction

I’m on the Astros in this one. I made a case for Boston on Monday only to have it blow up in my face as the Red Sox got blown out and I think Houston snags another win here. Bello is a solid option but I just think Brown outduels him here and the Astros get the win at home once again. Give me Houston.