Houston Astros vs NY Yankees Prediction 4/24/26 MLB Picks Today

The New York Yankees and the Houston Astros meet Friday in MLB action from Daikin Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Yankees vs. Houston Astros prediction.

Starting Pitching Matchup

The New York Yankees will send out Will Warren for the start here and Warren is 2-0 with a 2.49 ERA and 31 strikeouts this season. This will be Warren’s second career start against the Astros. Lance McCullers Jr. will start for Houston and is 1-1 with a 6.20 ERA and 21 strikeouts this season. In his last five starts against the Yankees, McCullers Jr. is 2-0 with a 2.97 ERA and 36 strikeouts.

New York Yankees Recap

The New York Yankees come into this game looking to add on to their 4-2 win over Boston last time out to sit at 16-9 this season. After this series, the Yankees will head on the road for a series against the Rangers.

Yankees Win 6 In A Row

Giancarlo Stanton has 22 hits with 6 doubles, 3 home runs and 13 RBIs while Ben Rice has 23 hits with 6 doubles, 8 home runs and 18 RBIs and Aaron Judge has 22 hits with 3 doubles, 9 home runs and 17 RBIs. Cody Bellinger also has 23 hits with 3 doubles, a triple, 3 home runs and 13 RBIs. Jazz Chisholm Jr. also has 16 hits with 5 doubles as well on the year.

Houston Astros Recap

The Houston Astros come into this game looking to add on to their 2-0 win over the Guardians from their last matchup to sit at 10-16 this season. After this series, the Astros will take on the Baltimore Orioles at home.

Astros Alternate Wins & Losses In 4 Straight

Yordan Alvarez has 33 hits with 8 doubles, 11 home runs and 26 RBIs while Christian Walker has 24 hits with 7 doubles, 5 home runs and 18 RBIs on the year. Jose Altuve’s chipped in 25 hits with 6 doubles, 3 home runs and 8 RBIs and Carlos Correa has 25 hits with 6 doubles, a home run and 13 RBIs. Cam Smith also has 21 hits with 5 doubles, 3 home runs and 11 RBIs. Yainer Diaz also has 14 hits with 23 doubles, a home run and 10 RBIs.

New York Yankees @ Houston Astros Betting Trends: April 24, 2026

• Probable Starting Pitcher: Lance McCullers Jr.      Record this season: 1-1      ERA: 6.20
• Home Record: 1-1
• Last 5 against Yankees: 0-0

Why the Houston Astros will win

• The Yankees have lost each of their last seven games as favorites against AL West opponents following a win.
• The Astros have won each of their last five games as home underdogs following a road win.
• The Yankees have failed to cover the run line in each of their last seven games as favorites against AL West opponents following a win.
• The Astros have covered the run line in 12 of their last 13 games as underdogs against AL East opponents following a road win.
• The Astros have won the first inning in each of their last three home games against American League opponents.
• The Astros have led after 3 innings in each of their last four night games against AL East opponents.
• The Astros have led after 5 innings in each of their last four night games against AL East opponents.

• Probable Starting Pitcher: Will Warren      Record this season: 2-0      ERA: 2.49
• Road Record: 0-0
• Last 5 against Astros: 0-0

Why the New York Yankees will win

• The Yankees have won each of their last six games.
• The Astros have lost each of their last six games against the Yankees following a win.
• The Yankees have covered the run line in each of their last six games.
• The Astros have failed to cover the run line in each of their last six games against the Yankees following a win.
• The Astros have lost the first inning in three of their last four night games.
• The Astros have trailed after 3 innings in eight of their last nine night games against opponents that held a winning record.
• The Astros have trailed after 5 innings in eight of their last nine home games against opponents that held a winning record.

Total Runs Facts

• Each of the Astros’ last eight night games against American League opponents have gone OVER the total runs line.
• Each of the Yankees’ last six night games against American League opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last 11 games as underdogs.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Yankees’ last five games at Daikin Park.

Houston Astros Player Prop Facts

• Yordan Alvarez has hit a home run in four of the Astros’ last five home games.
• Lance McCullers Jr. has recorded six or more strikeouts in five of his last six appearances with the Astros as underdogs against AL East opponents.
• Isaac Paredes has recorded at least one hit in each of his last 11 appearances against AL opponents.
• Yordan Alvarez ranks 1st in the league in Home Runs (11) this season.

New York Yankees Player Prop Facts

• Aaron Judge has hit at least one home run in three of the Yankees’ last four games against AL West opponents.
• Paul Goldschmidt has recorded at least one hit in each of his last 10 road appearances against the Astros.
• Ben Rice ranks 2nd amongst qualified players for Slugging Percentage (.716) this season.

Matchup/League Facts

• The Astros rank 1st in the league for doubles this season (59).
• The Astros rank 30th in the league for ERA this season (5.81).
• The Yankees rank 1st in the league for ERA this season (3.07).
• The Yankees rank 29th in the league for hits this season (181).

New York Yankees vs. Houston Astros Prediction

I’m on the Yankees here. I get the case to be made for the Astros in certain spots as they look like they’ve finally woken up after their slow start to the year. However, McCullers Jr. is still a liability on the mound and the Yankees have the bats to knock him around while Will Warren has still been a solid contributor to this Yankee rotation and I think the Yanks beat up on McCullers Jr. in this one. Give me the Yankees.