Astros vs Yankees Prediction 9/3/25 MLB Picks Today

The New York Yankees and the Houston Astros meet Wednesday in MLB action from Daikin Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Astros vs Yankees Prediction.

Starting Pitching Matchup

The New York Yankees will send out Will Warren for the start here and Warren is 8-6 with a 4.30 ERA and 149 strikeouts this season. This will be Warren’s first career start against the Astros. Jason Alexander will get the start for the Astros here and is 4-1 with a 4.61 ERA and 46 strikeouts this season. In his career, Alexander is 1-0 with a 2.79 ERA and 8 strikeouts against the Yankees. 

New York Yankees Recap

The New York Yankees come into this game looking to add on to their 7-1 win over Houston from Tuesday’s matchup to sit at 77-61 this season. After this game, the Yankees will head home for a massive series against the Blue Jays.

Yankees Win 8 Of Their Last 9

Aaron Judge leads the Yankees with 144 hits including 41 home runs, 95 RBIs, 26 doubles and a .323 batting average along with 8 stolen bases. Anthony Volpe’s also had 26 doubles with 15 stolen bases, 18 home runs and 65 RBIs while Jasson Dominguez has added 17 doubles of his own. Paul Goldschmidt has 121 hits with 30 doubles and a .284 batting average while Volpe also has 125 strikeouts so far this season. Ben Rice also has 91 hits with 21 doubles, 22 home runs and 49 RBIs while Cody Bellinger has 25 homers with 79 RBIs and Austin Wells has 18 home runs and 59 RBIs with Bellinger logging 21 doubles and Wells chipping in 16 doubles. Trent Grisham also has 26 home runs and 51 RBIs and Jazz Chisholm Jr. has 25 home runs and 64 RBIs so far this season.

Why the New York Yankees will win

• The Yankees have won each of their last eight road games against the Astros.
• The Astros have lost each of their last seven games against the Yankees following a home loss.
• The Yankees have covered the run line in each of their last nine road games against the Astros.
• The Astros have failed to cover the run line in each of their last nine games against the Yankees following a home loss.

New York Yankees Player Prop Facts

• Jazz Chisholm has hit at least one home run in three of his last four road appearances against the Astros.
• Paul Goldschmidt has recorded at least one hit in each of his last nine road appearances against the Astros.
• Aaron Judge ranks 1st amongst qualified players for Batting Average (.325) this season.

Houston Astros Recap

The Houston Astros come into this game looking to bounce back from their loss at the hands of the Yankees on Tuesday to sit at 76-63 this season. After this series, the Astros will head on the road for a set against the division rival Texas Rangers.

Astros Drop 3 Of Last 4

Jose Altuve has 136 hits including 20 doubles, 23 home runs and 65 RBIs. Jeremy Pena also has 125 hits with 23 doubles, 14 homers and 50 RBIs with 19 stolen bases as well. Jake Meyers has 15 doubles as well and Christian Walker has 21 home runs and 74 RBIs but has also accrued a team-high 142 strikeouts so far this season. Altuve also has 9 stolen bases while Jake Meyers has 14 stolen bases this season. Isaac Paredes also has 19 home runs with 50 RBIs of his own and Cam Smith has contributed 8 homers and 49 RBIs. Yainer Diaz has also chipped in 114 hits with 18 home runs, 55 RBIs and 16 doubles.

Why the Houston Astros will win

• The Astros have won each of their last 10 night games against AL East opponents following a loss.
• The Yankees have lost each of their last three games as favorites against the Astros following a win.
• The Astros have covered the run line in each of their last seven games as home underdogs against American League opponents following a loss.
• The Yankees have failed to cover the run line in each of their last seven Wednesday road games against AL West opponents.

Houston Astros Player Prop Facts

• Christian Walker has hit a home run in three of the Astros’ last five games against AL East opponents.
• Jake Meyers has recorded at least one hit in each of his last 10 appearances against AL opponents.
• Jeremy Pena ranks 5th amongst qualified players for Batting Average (.304) this season.

Total Runs Facts

• Four of the Astros’ last five night games against AL East opponents have gone OVER the total runs line.
• Seven of the Yankees’ last nine road games against AL West opponents have gone UNDER the total runs line.

Astros vs Yankees Prediction

I’m on the over here. I get the case to be made for either side in this game, but the thing here is that Will Warren’s had issues on the road this season. While Alexander pitched well against the Yankees, it’s hard to hold the same team down twice, especially when it’s one of the best teams in the league at hitting right-handed pitching. Give me the over in this one.